Temporal trends and patterns for early- and late-onset adult liver cancer incidence vary by race/ethnicity, subsite, and histologic type in the United States from 2000 to 2019

Cancer Causes & Control, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 9, 2025

To examine incidence trends and patterns for early- late-onset liver cancer. Liver intrahepatic bile duct (IBD) cancers diagnosed between 2000 2019 were acquired from 22 SEER registries. Variables included early-onset (20-49) vs. (50+), anatomic subsite, histologic type (hepatocellular carcinoma [HCC] IBD cholangiocarcinoma [ICC]), sex, race/ethnicity. Age-standardized rates calculated using SEER*Stat. Jointpoint regression analysis was employed to estimate the annual percent change (APC) average APC (AAPC) with pairwise comparisons trend by sex race/ethnicity stratified age subsite. cancer decreased among (AAPC [95% CI] - 2.39 [- 2.74, 2.07]) but increased patients (2.85 [2.71, 3.01]), primarily driven HCC (3.60 [3.50, 3.71]). both ages ICC annually increasing 7.92% (6.84, 9.26) 6.32% (5.46, 8.86) patients. Early-onset displayed comparable across racial/ethnic groups; however, showed more variation, particularly American Indian/Alaska Native/Asian Pacific Islander (AI/AN/API) populations, which experienced a significant decrease in incidence, thereby narrowing gap other groups. For IBD, an identical pattern of non-Hispanic Blacks (NHBs) compared Hispanics coincidence test p = 0.1522, parallel observed sexes (p 0.5087). Late-onset continues rise, except NHB AI/AN/API, where have started over past 4-5 years. Early increase all

Language: Английский

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COVID-19 pandemic shifted epidemiology for cancer screening sites: breast, cervix, colon, and rectum

Frontiers in Oncology, Journal Year: 2025, Volume and Issue: 14

Published: Jan. 30, 2025

Background This study aimed to assess the epidemiological changes in breast, cervical, colon, and rectal cancers Kazakhstan before during COVID-19, including early-onset cancer (EOC) diagnosed between ages of 20 49, using data from oncological service Republic for 2017–2022 period. Methods The cohort comprised patients aged 49 years 50 older [late-onset (LOC)] total number each year period 2017 2022 or cancer. In order indicate a difference one-time intervals characterize global trend over entire period, annual percentage change (APC) average APC (AAPC) were calculated, respectively. Results Breast detection rates increased by 22.8% EOC 15.9% LOC 2022, AAPC 4.3% 3.6% LOC. During COVID-19 restriction breast decreased 6.1% 15.6% Cervical 2.3% 7.5% 0.9% 1.6% cervical 11.3% 3.1% Colon 18.4% 14.3% 3.7% 2.9% colon 14.4% 5.8% Rectal 13.6% 19.2% 3.0% 3.9% 18.6% 12.0% Conclusion indicators population screening worsened COVID pandemic; rate EOC, while there was an increase 38.0% men 8.0% 31.1% women.

Language: Английский

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“It’s a low-key thing of eugenics”: Disability reproductive injustice in barriers to cervical cancer screening for people with disabilities during the COVID-19 pandemic

Social Science & Medicine, Journal Year: 2025, Volume and Issue: 369, P. 117807 - 117807

Published: Feb. 3, 2025

Cervical cancer screening (CCS) is a critical component of preventative sexual and reproductive healthcare, yet there are disparities in access to CCS for people with disabilities. This qualitative community-engaged study uses the disability justice framework examine how COVID-19 pandemic impacted disabilities' experiences Canada. From May 2022 March 2023, semi-structured interviews were conducted 40 women gender-diverse physical, sensory, cognitive, and/or mental health Results from thematic analysis indicate that barriers before during characterized by inaccessibility, ableism intersecting forms oppression, provider distrust, deprioritization disregard disabled people's autonomy. Grounded these findings, this article situates healthcare like as concern. Amplified pandemic, enacted injustice through everyday micro-eugenics devalued Barriers must be addressed collaboration communities. Guided participant insights, recommendations include making services more accessible available disabilities, especially aftermath public emergencies disproportionately impact

Language: Английский

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Trends in uptake of cancer screening among people with severe mental illness before and after the COVID‐19 pandemic in Japan: A repeated cross‐sectional study

Psychiatry and Clinical Neurosciences Reports, Journal Year: 2025, Volume and Issue: 4(1)

Published: Feb. 2, 2025

Abstract Aim The aim of this study was to investigate trends in cancer screening participation among people with severe mental illness (PSMI) from periods before and after the COVID‐19 pandemic. Methods In repeated cross‐sectional study, we used anonymized datasets on municipal PSMI Okayama City. data covered fiscal year (FY) 2018 FY2022; database Medical Payment for Services Supports Persons Disabilities. were defined as those schizophrenia or related psychotic disorders (F20–29) bipolar disorder (F30 F31), identified using International Classification Diseases , Tenth Revision, codes. analysis included men women aged 40–69 years colorectal lung screening; 50–69 gastric breast 20–69 cervical screening. Municipal rates calculated each FY. Results For all types, FY2020 (colorectal: 9.0%; lung: 11.6%; gastric: 4.9%; breast: 6.2%; cervical: 6.1%) lower than FY2019 (11.5%, 14.0%, 6.5%, 9.3%, 8.3%, respectively). FY2022, (9.9%, 12.9%; 5.3%; 8.0%, 6.9%, respectively) recovered, but remained low. Conclusion This showed that very low, both Efforts encourage population are urgently needed.

Language: Английский

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Disparities in Cancer Screening Among the Foreign-Born Population in the United States: A Narrative Review

Cancers, Journal Year: 2025, Volume and Issue: 17(4), P. 576 - 576

Published: Feb. 8, 2025

Background: The foreign-born population in the United States has reached a record high over last three years. Significant disparities cancer screening rates exist among this population, resulting later-stage diagnoses and worse outcomes. This narrative review explores sociodemographic factors, barriers, interventions influencing individuals U.S. Methods: A comprehensive of studies was conducted to assess colorectal, cervical, breast immigrants. Factors examined include length residence, race ethnicity, income, education, citizenship, insurance, usual source care, language, medical literacy, cultural barriers. Furthermore, effectiveness educational interventions, patient navigators, at-home testing addressing these evaluated. Results: Immigrants have lower for compared U.S.-born individuals, with largest observed colorectal cancer. gaps shorter duration Asian income education levels. Lack health insurance care are currently most significant barriers screening. Interventions such as navigation, shown moderate success improving rates, though data on their remain limited. Conclusions: Addressing within is essential, especially immigrant continues reach numbers. Targeted needed improve groups lowest completion rates. Future research should prioritize larger sample sizes, longitudinal studies, utility new technologies artificial intelligence.

Language: Английский

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Virtual Health Care Encounters for Lung Cancer Screening in a Safety-Net Population: Observations From the COVID-19 Pandemic

JCO Clinical Cancer Informatics, Journal Year: 2025, Volume and Issue: 9

Published: March 1, 2025

The COVID-19 pandemic disrupted normal mechanisms of health care delivery and facilitated the rapid widespread implementation telehealth technology. As a result, effectiveness virtual visits in diverse populations represents an important consideration. We used lung cancer screening as prototype to determine whether subsequent adherence differs between in-person encounters urban, safety-net system. conducted retrospective analysis initial low-dose computed tomography (LDCT) ordered for from March 2020 through February 2023 within Parkland Health, integrated provider Dallas County, TX. collected data on patient characteristics, visit type, LDCT completion electronic medical record. Associations among these variables were assessed using chi-square test. also performed interaction analyses according type. Initial orders placed total 1,887 patients, whom 43% female, 45% Black, 17% Hispanic. Among orders, 343 (18%) during visits. From August 2020, 79 163 (48%) visits; after that time, 264 1,724 (15%) No characteristics significantly associated with type (in-person v virtual) or completion. Rates 95% 97% (P = .13). In population, patients likely complete postvisit when encounter encounter.

Language: Английский

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Colorectal Cancer Screening Amid COVID‐19 in Japan: Analysis From the 2021–2022 JACSIS Study

Cancer Medicine, Journal Year: 2025, Volume and Issue: 14(8)

Published: April 1, 2025

ABSTRACT Background Maintaining a high participation rate is crucial for effective colorectal cancer (CRC) screening. The COVID‐19 pandemic placed significant burden on healthcare facilities, which hindered CRC screening efforts. However, the effects of prolonged remain unclear. Methods We analyzed data from Japan and Society Internet Survey in September 2021 2022 to examine over past year. also evaluated association between status, future intentions, background characteristics, anxiety about measured using fear coronavirus disease 2019 scale (FVC‐19S) survey.. Results Of 13,261 respondents, 40.5% reported undergoing 2021, while 48.7% did so 2022. Multivariable Poisson regression analysis showed that factors associated with included being male (adjusted incidence risk ratio [aIRR] 1.07, 95% confidence interval [CI]; 1.00–1.14, p = 0.026), age 40s (aIRR 0.89, CI; 0.81–0.97, 0.012) 50s 0.82–0.98, 0.011), unmarried 0.88, 0.82–0.95, 0.001), employment status such as self‐employed 0.86, 0.76–0.97, or unemployed 0.81–0.92, < 0.01). Having an FVC‐19S score below 21 was factor 0.95, 0.90–1.00, 0.032). Conclusions Although rates increased 2022, proportion respondents still not screening, highlighting importance assessing long‐term impact identifying make less accessible.

Language: Английский

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COVID-19 pandemic interruption of breast cancer screening is linked to clinical upstaging at presentation: the roles of demographics, socioeconomic status and unmet social needs

Breast Cancer Research and Treatment, Journal Year: 2025, Volume and Issue: unknown

Published: May 15, 2025

Language: Английский

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Blood-Based Multi-Cancer Early Detection Tests (MCEDs) as a Potential Approach to Address Current Gaps in Cancer Screening

Cancer Control, Journal Year: 2024, Volume and Issue: 31

Published: Jan. 1, 2024

Screening and early detection is one of the most effective approaches to reduce population-level impact cancer. Novel screening such as multi-cancer tests (MCEDs) may further cancer incidence mortality. Many MCEDs detect fragments circulating DNA containing mutations that originated from tumour cells, thereby informing both presence cell-type origin. In this review, we examine current evidence a potential tool improve population-based outcomes. We review role address low participation rates, disparities among underserved populations, changing epidemiology common cancers, absence for many types. have increase in programs, they be less invasive than other procedures, can screen multiple types appointment. Additionally, due lack specialized collection equipment needed these tests, underscreened populations targeted could gain greater access screening. Finally, because without are moderately increasing western efficacious sites alleviate burden patient While offer great promise, considerable limitations gaps must addressed. Notable include scenarios where does not survival outcomes, costs on health care resources false positives, reassurance with subsequent adherence existing protocols.

Language: Английский

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A Final Report on the Real Impact of the COVID-19 Pandemic on the Diagnosis of Gastrointestinal Cancer in Akita Prefecture, Japan in 2022

The Tohoku Journal of Experimental Medicine, Journal Year: 2024, Volume and Issue: 263(2), P. 161 - 168

Published: Jan. 1, 2024

The long-term impact of the coronavirus disease 2019 (COVID-19) pandemic on disruption gastrointestinal cancer diagnoses remains unclear. This study investigated actual esophagogastric (EGC) and colorectal (CRC) up to third year in Akita Prefecture, Japan, using population-based registry data. We collected data annual number EGC CRC a database from collaborative Prefecture hospital-based registration. net cancers diagnosed first three years (2020-2022) were compared with those before (2017-2019). Changes proportion stage initial treatment for after then compared. total EGCs was 9.3% lower than before, probably due its declining trend. CRCs exceeded that suggesting successful recovery diagnostic procedure. stages remained largely unchanged onset pandemic. Based pandemic, caused by is settling down without any substantial progression, even area highest incidence all Japan.

Language: Английский

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