The influence of specific weather types on stroke occurrence: an analysis of 23,000 patients from Augsburg, Germany DOI
Jonathan Simon, Michael Ertl,

Markus Naumann

et al.

International Journal of Environmental Health Research, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 12

Published: Sept. 20, 2024

For the first time, relationships between large-scale weather types and local stroke events in urban area of Augsburg, Germany are analyzed. Over 23,000 cases (2006 - 2020) were standardized to account for long-term trends seasonality. Using ERA5 reanalysis data, a composite analysis identified stroke-related atmospheric variables, while seasonal classified via neural network algorithm self-organizing maps. Cyclonic westerlies during cold season, which transport warm air masses from Atlantic Ocean Germany, major risk factor ischemic stroke, colder easterly conditions reduced incidence. In both anticyclonic westerly/northerly advection, leading slightly warmer or distinctly temperatures, linked increased risk. Additionally, hemorrhagic strokes season triggered by contrary those associated with transitory attacks.

Language: Английский

The association between short-term apparent temperature exposure and human coagulation: A time-series study from Beijing, 2014–2023 DOI Creative Commons
Yi Zhang, Tiancheng Wang, Jiaqi Shi

et al.

Environment International, Journal Year: 2025, Volume and Issue: 195, P. 109262 - 109262

Published: Jan. 1, 2025

A growing body of evidence suggests that non-optimal ambient temperatures are associated with increased incidence rate and mortality thromboembolic diseases. We aim to investigate the association between apparent temperature (AT) coagulation, which is a central pathological link in formation thrombi. In this study, we conducted time series analysis using data from 18,894 participants collected health check-up center Beijing 2014 2023, validated our findings 20,549 an andrology outpatient clinic. The daily mean AT was calculated on temperature, relative humidity, wind speed Beijing. Participants were matched lagged moving average (0-7 days) based their specific examination dates. study employed generalized additive models analyzed linear nonlinear associations coagulation indices. results indicated heat resulted shortened prothrombin activated partial thromboplastin time, whereas cold thrombin time. Fibrinogen showed increase at both high low temperatures. Logistic regression revealed risk hypercoagulable state environments compared moderate temperatures, significant observed under extreme conditions. Subgroup analyses by sex age, sensitivity analyses, external validation robust. support can augment blood coagulability through distinct stages cascade, thereby leading elevated

Language: Английский

Citations

0
Hourly-level association between ambient temperature and onset of acute chest pain: a case-crossover study in Foshan, China DOI

Wanquan Li,

Zitong Zhuang,

Hualiang Lin

et al.

International Journal of Biometeorology, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 24, 2025

Language: Английский

Citations

0
Meta-analysis of heat-induced changes in cardiac function from over 400 laboratory-based heat exposure studies DOI Creative Commons
Robert D. Meade, Ashley P. Akerman, Sean R. Notley

et al.

Nature Communications, Journal Year: 2025, Volume and Issue: 16(1)

Published: March 14, 2025

Heat waves are associated with increased fatalities from adverse cardiovascular events attributed to the negative effects of heat on cardiac function. However, scientific understanding acute adjustments has come primarily laboratory experiments employing insulated and encapsulated heating modalities, most commonly water-perfused suits. We evaluated whether findings those studies reflect responses during more natural exposures hot ambient conditions simulated in climate-controlled chambers by synthesizing over 400 laboratory-based exposure (6858 participant-exposures) published between 1961–2024. Among all included studies, median (interquartile range) elevations core temperature heart rate baseline end-exposure were 0.9 (0.5–1.3)°C 27 (15–40) beats/min. Multilevel mixed-effects meta-analyses revealed exacerbated rate, output, pressure product (estimate workload) blunted falls systolic participants heated via modalities. Leveraging large dataset, we also provide empirical estimates body a wide range experienced waves. With rising global temperatures, ecologically-minded physiological research is needed improve stress further development robust climate health models evidence-based heat-health guidance. Understanding heat-induced changes function encapsulated, water-based Here, authors show that these overestimate burden compared

Language: Английский

Citations

0
Associations of compound hot extremes and heat waves with first-ever stroke morbidity in the context of climate change DOI Creative Commons

Chenlu Yang,

Ming‐Wei Wang, Zhoupeng Ren

et al.

Advances in Climate Change Research, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

Citations

0
Mechanistic insights into the cardiovascular effects of acute heat exposure: A multi-omics analysis based on a randomized crossover trial DOI Creative Commons
Xinlei Zhu, Xihao Du, Yixiang Zhu

et al.

Environment International, Journal Year: 2025, Volume and Issue: 199, P. 109495 - 109495

Published: April 23, 2025

Heat exposure has been identified as a significant contributory factor in the development of cardiovascular diseases, but biological mechanisms are not yet fully elucidated. We conducted randomized crossover trial healthy adults Shanghai, China. Each subject was alternatively exposed to moderate temperature (22 °C) and elevated (32 chamber for 2 h random order. Blood pressure (BP) arterial stiffness were measured before after each session. Genome-wide DNA methylation, untargeted serum proteomics, metabolomics, 15 targeted biomarkers analyzed. Linear mixed-effects models used analyze data. The pathway enrichment performed at ingenuity analysis platform. network-based xMWAS further conducted. A total 30 participants (15 males females) completed trial, with an average age 21.7 ± 1.5 years. associated higher pulse wave velocity (4.4 %, 95 % CI: 0.2, 6.8), augmentation index normalized 75 bpm heart rate (190.7 19.0, 362.3) reflection magnitude (35.9 12.3, 59.5). Exposure heat significantly changes on systemic inflammation, oxidative stress, 1 coagulation, lipid metabolism, atherosclerotic alterations. Multi-omics analyses indicated heat-induced perturbations pathways mostly related metabolism disorder. Acute might impair function promote multiple adverse processes, especially those atherosclerosis progression increase plaque instability.

Language: Английский

Citations

0
Differentiating the impact of non-optimum temperature and temperature variability on cause-specific cerebrovascular mortality: An individual-level, case-crossover study in Shanghai, China DOI
Xiaozhen Su, Yifeng Qian,

Ying Liu

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2025, Volume and Issue: 299, P. 118339 - 118339

Published: May 20, 2025

Language: Английский

Citations

0
Umweltfaktoren und Schlaganfall – Vervollständigung präventiver Maßnahmen DOI

Lino Braadt,

Michael Ertl,

M. Naumann

et al.

DGNeurologie, Journal Year: 2025, Volume and Issue: unknown

Published: May 21, 2025

Citations

0
Hourly Relative Humidity and Fall Injuries in China: A Nationwide Case-Crossover Study Based on 4.19 Million Cases DOI Creative Commons

Weiquan Zeng,

Yuliang Er,

Pengpeng Ye

et al.

Environment & Health, Journal Year: 2025, Volume and Issue: unknown

Published: May 25, 2025

Language: Английский

Citations

0
The influence of specific weather types on stroke occurrence: an analysis of 23,000 patients from Augsburg, Germany DOI
Jonathan Simon, Michael Ertl,

Markus Naumann

et al.

International Journal of Environmental Health Research, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 12

Published: Sept. 20, 2024

For the first time, relationships between large-scale weather types and local stroke events in urban area of Augsburg, Germany are analyzed. Over 23,000 cases (2006 - 2020) were standardized to account for long-term trends seasonality. Using ERA5 reanalysis data, a composite analysis identified stroke-related atmospheric variables, while seasonal classified via neural network algorithm self-organizing maps. Cyclonic westerlies during cold season, which transport warm air masses from Atlantic Ocean Germany, major risk factor ischemic stroke, colder easterly conditions reduced incidence. In both anticyclonic westerly/northerly advection, leading slightly warmer or distinctly temperatures, linked increased risk. Additionally, hemorrhagic strokes season triggered by contrary those associated with transitory attacks.

Language: Английский

Citations

1