Are the Risk Factors for Bronchopulmonary Dysplasia and Retinopathy of Prematurity in Very Low-Birth-Weight Infants the Same? DOI Creative Commons
Hui Wu, Juan Zhang, Jing Zhang

et al.

Children, Journal Year: 2025, Volume and Issue: 12(4), P. 509 - 509

Published: April 15, 2025

Background/Objectives: Bronchopulmonary dysplasia (BPD) and retinopathy of prematurity (ROP) affect the prognosis preterm infants, their coexistence is a risk factor for poor long-term outcomes in very low-birth-weight infants. However, there has been limited in-depth assessment common independent factors BPD ROP within same cohort. Therefore, we aimed to investigate infants born at ≤32 weeks gestation explore interaction between these two diseases. Methods: The participants were divided into four groups: BPD+ROP+, BPD-ROP-, BPD+ROP-, BPD-ROP+. Gestational age, birth weight, maternal pregnancy complications, postnatal diseases, treatment conditions compared among groups. Subsequently, univariate multivariate binary logistic regression analyses conducted ROP. Results: Common included gestational age prolonged oxygen therapy. analysis revealed that (OR: 4.44; 95% CI: 3-6.57), intubation resuscitation 2.35; 1.09-5.05), mechanical ventilation duration ≥ 7 days 1.01; 1.01-1.01), total therapy 3.13; 1.28-7.64) BPD. Additionally, 0.66; 0.54-0.81) 1.02; 1-1.03) Conclusions: proper control concentration therapy, along with minimization time, crucial reducing incidence both

Language: Английский

Structural Equation Modelling of Retinopathy of Prematurity Treatment Integrating Both Physical and Clinical Effects DOI Open Access
J.L. García-Serrano, Olena Protsyk, Teresa Domech‐Serrano

et al.

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(2), P. 297 - 297

Published: Jan. 7, 2025

Background: We sought to develop a structural equation model (SEM) identifying physical and clinical risk factors associated with treatment for retinopathy of prematurity (ROP). Methods: This retrospective, observational, case-control study included 314 infants screened ROP between April 2004 July 2024. A bivariate binary logistic regression model, decision tree, were employed more general requiring treatment. Results: In the SEM, significantly retinal avascular area according disk diameter (DD) (p < 0.001), weekly vascularisation rate (DD/w) duration intubation (days) 0.001). addition, following significant associations identified in both analysis SEM: lower gestational age 0.001) birth weight <0.001) greater area; low postnatal gain 0.027) was slow vascularisation; sepsis ductus arteriosus need transfusion longer mechanical ventilation (IMV). Conclusions: Lower age, weight, sepsis, arteriosus, transfusion, increase this association is represented through three intermediate endogenous variables, namely, temporal retina, rate, IMV.

Language: Английский

Citations

0

Etiological Explanation DOI
Olaf Dammann

Published: Jan. 1, 2025

Language: Английский

Citations

0

Are the Risk Factors for Bronchopulmonary Dysplasia and Retinopathy of Prematurity in Very Low-Birth-Weight Infants the Same? DOI Creative Commons
Hui Wu, Juan Zhang, Jing Zhang

et al.

Children, Journal Year: 2025, Volume and Issue: 12(4), P. 509 - 509

Published: April 15, 2025

Background/Objectives: Bronchopulmonary dysplasia (BPD) and retinopathy of prematurity (ROP) affect the prognosis preterm infants, their coexistence is a risk factor for poor long-term outcomes in very low-birth-weight infants. However, there has been limited in-depth assessment common independent factors BPD ROP within same cohort. Therefore, we aimed to investigate infants born at ≤32 weeks gestation explore interaction between these two diseases. Methods: The participants were divided into four groups: BPD+ROP+, BPD-ROP-, BPD+ROP-, BPD-ROP+. Gestational age, birth weight, maternal pregnancy complications, postnatal diseases, treatment conditions compared among groups. Subsequently, univariate multivariate binary logistic regression analyses conducted ROP. Results: Common included gestational age prolonged oxygen therapy. analysis revealed that (OR: 4.44; 95% CI: 3-6.57), intubation resuscitation 2.35; 1.09-5.05), mechanical ventilation duration ≥ 7 days 1.01; 1.01-1.01), total therapy 3.13; 1.28-7.64) BPD. Additionally, 0.66; 0.54-0.81) 1.02; 1-1.03) Conclusions: proper control concentration therapy, along with minimization time, crucial reducing incidence both

Language: Английский

Citations

0