Nutrition and Cancer,
Journal Year:
2024,
Volume and Issue:
77(2), P. 188 - 199
Published: Oct. 6, 2024
There
are
currently
more
than
3.3
million
prostate
cancer
(PC)
survivors
in
the
United
States.
Conformance
with
national
dietary
guidelines
and
a
good
diet
quality
may
lower
risk
for
Gleason
grade
progression
PC
patients.
Assessing
nutritional
status
of
is
thus
paramount
importance
from
public
health
nutrition
perspective.
We
used
24-h
recall
data
National
Health
Nutrition
Examination
Surveys
(NHANES)
to
systematically
estimate
nutrient
intakes
n
=
360
(which
be
extrapolated
represent
1,841,030
survivors)
aged
70.69
years
on
average,
contrasted
results
daily
goals
(DNG)
2020–2025
Dietary
Guidelines
Americans
(DGA).
Diet
was
found
generally
poor,
DNG
as
specified
DGA
were
not
met
many
micronutrients,
including
calcium,
magnesium
potassium.
had
an
insufficient
intake
vitamins
(including
A,
C,
D
E),
did
meet
recommendations
fiber.
Racial
disparities
reflected
overall
DQ
Non-Hispanic
Black
participants.
Our
reiterate
need
assessment
counseling
improve
JAMA Network Open,
Journal Year:
2025,
Volume and Issue:
8(2), P. e2460785 - e2460785
Published: Feb. 26, 2025
Importance
Prostate
cancer
(PCa)
remains
a
leading
cause
of
cancer-related
death
among
men
in
the
US.
Objective
To
evaluate
association
healthy
lifestyle
and
dietary
behaviors
with
survival
after
nonmetastatic
PCa
diagnosis
multiethnic
population.
Design,
Setting,
Participants
This
prospective
cohort
study
was
conducted
aged
45
to
75
years
enrolled
between
1993
1996
Multiethnic
Cohort
study.
completed
questionnaire
(2003-2008)
were
followed
up
until
or
loss
follow-up.
Data
analyzed
from
January
10,
2023,
May
20,
2024.
Exposures
Lifestyle
patterns
assessed
using
3
behavior
scores
13
indices
(4
prioritized
scores:
Healthy
Eating
Index–2015,
Healthful
Plant-Based
Diet
Index,
Dietary
Inflammatory
Empirical
Index
for
Hyperinsulinemia).
Main
Outcomes
Measures
Cox
proportional
hazards
models
used
multivariable-adjusted
associations
each
score
all-cause,
cardiovascular
disease
(CVD),
PCa-specific
mortality.
Results
A
total
2603
(mean
[SD]
age,
69.6
[7.1]
years)
up,
1346
deaths
documented,
including
356
(24.6%)
CVD
197
(14.6%)
PCa.
The
median
(IQR)
follow-up
10.9
(IQR,
6.8-12.7)
return
14.5
11.8-18.0)
diagnosis.
2021
Behavior
Score
associated
reduced
risks
all-cause
(hazard
ratio
[HR]
per
point,
0.69;
95%
CI,
0.63-0.77)
CVD-related
(HR,
0.67;
0.56-0.79)
also
lower
risk
mortality
African
American
0.46;
0.24-0.88)
but
not
other
racial
ethnic
groups.
Comparing
quintile
5
(highest
score)
1
(lowest
score),
Hyperinsulinemia
positively
1.37;
1.02-1.84)
1.96;
1.15-3.33)
mortality,
whereas
0.75;
0.58-0.97);
findings
statistically
significant
0.44-1.03).
No
found
Conclusions
Relevance
In
this
patients
PCa,
healthier
lifestyles
improved
overall
survival.
Given
predominance
non–PCa-specific
deaths,
these
support
need
health
counseling
treat
comorbidities
Biomolecules,
Journal Year:
2025,
Volume and Issue:
15(4), P. 464 - 464
Published: March 21, 2025
Wheat
germ
oil
(WGO),
derived
from
the
nutrient-dense
of
wheat
kernels,
is
a
functional
bioactive
product,
known
for
its
rich
composition
essential
fatty
acids,
sterols,
tocopherols,
and
polyphenols.
This
study
aimed
to
comprehensively
profile
molecular
therapeutic
properties
WGO,
focusing
on
antioxidant,
cytotoxic,
anti-inflammatory
activity.
Using
advanced
analytical
techniques
such
as
gas
chromatography-mass
spectrometry
(GC-MS),
Fourier
Transform
Infrared
(FTIR)
spectroscopy,
fluorescence
analysis,
WGO
was
shown
contain
high
levels
linoleic
acid
(45.3%),
squalene
(2.52
g/100
g),
displayed
selective
cytotoxicity,
inhibiting
cancer
cells'
viability
in
melanoma,
prostate,
colorectal
cell
lines,
but
not
normal
cells,
highlighting
chemoprevention
potential.
Furthermore,
significantly
reduced
LPS-induced
nitric
oxide
IL-6
production
macrophages,
with
effects
plateauing
at
higher
doses.
The
3D
spectra
showed
significant
decrease
intensity
when
human
serum
albumin
interacted
polyphenol
fraction,
indicating
strong
binding
affinity
stable
complex
formation.
These
findings
emphasize
nutritional
potential
natural
agent,
warranting
further
mechanistic
investigation
broader
applications
health
disease
management.
Current Opinion in Urology,
Journal Year:
2024,
Volume and Issue:
34(5), P. 352 - 357
Published: May 31, 2024
Purpose
of
review
We
summarize
the
latest
evidence
regarding
impact
plant-based
diets
on
urological
and
planetary
health
to
facilitate
patient
counseling
research
dietary
intervention.
Recent
findings
Studies
have
highlighted
association
with
a
lower
risk
multiple
conditions
including
prostate
cancer,
erectile
dysfunction,
benign
prostatic
hyperplasia,
nephrolithiasis,
as
well
benefits
for
health.
Summary
Plant-based
are
associated
numerous
that
co-promote
Indian Journal of Urology,
Journal Year:
2024,
Volume and Issue:
40(3), P. 143 - 144
Published: July 1, 2024
Prostate
cancer
is
on
the
march!
As
per
latest
Lancet
Commission
report,
new
prostate
cases
are
likely
to
double
from
1.4
million
in
2020
2.9
2040.
The
number
of
annual
deaths
due
projected
rise
by
85%,
375,000
nearly
700,000
same
period.
maximum
impact
will
be
felt
low-
and
middle-income
countries,
like
India,
paucity
resources
absence
early
diagnoses.[1]
This
also
clearly
reflected
registry
data
presented
Sankarapillai
et
al.
current
issue
journal.[2]
While
advances
access
conventional
treatments
such
as
surgery,
radiation,
various
forms
systemic
therapy
need
accelerated,
there
a
growing
recognition
for
more
holistic
individualized
approach
incorporating
aspects
lifestyle
medicine
improve
oncological
outcomes
quality
life
(QoL)
patients.
Indeed,
coming
years,
it
that
diet,
exercise,
stress
management,
sleep,
healthy
choices
gain
frontline
status
powerful
adjuncts
care
these
A
nutritious
diet
an
important
component
can
prevent
many
chronic
diseases.
There
accumulating
evidence
rich
fruits,
vegetables,
nuts,
whole
grains
lower
risk
recurrent
cancer.
In
recent
cohort
study
2062
patients
diagnosed
with
nonmetastatic
cancer,
higher
intake
plant-based
foods
was
associated
decrease
progression,
besides
providing
other
health
benefits.[3]
It
perhaps
time
made
aware
studies,
nutritional
counseling
incorporated
part
multidisciplinary
this
disease.
Alcohol
tobacco
smoke
WHO
Grade
1
carcinogens,
now
their
association
well.[4,5]
Smoking
cessation
programs
support
services
eliminate
or
alcohol
go
long
way
enhancing
odds
cancer-free
life.
Regular
physical
including
cardiorespiratory
strength
training
components,
frequently
advised
physicians
reduce
fatigue,
cardiovascular
health,
enhance
mental
well-being.
particular,
androgen
deprivation
may
especially
benefit
exercise
regimens
ensuring
preservation
lean
muscle
mass,
decreasing
fat
accumulation,
counteracting
which
seen
very
commonly
treatments.
meta-analysis
six
RCTs
(332
patients),
authors
found
interventions
ranging
2–12
months
resulted
increased
fitness,
improved
QoL,
and,
surprisingly,
decreased
PSA
progression
active
surveillance
cancer.[6]
We
surely
do
not
wait
effect
proven
beyond
doubt
before
advising
our
along
lines.
positive
effects
graded
structured
regimen
should
enjoyed
all,
irrespective
diagnosis
age.
use
wearable
devices
monitor
motivate
exercise-
sleep-related
provide
long-lasting
benefits
patients.[7]
have
profound
psychological
result
anxiety
depression.
Deep
breathing
exercises,
yoga,
mindfulness
meditation
few
reduction
strategies
extremely
beneficial
health.
suggest
methods
assist
lowering
levels
fatigue
sleep
receiving
treatment
cancer.[8]
Incorporating
services,
groups,
into
potentially
overall
well-being
emotional
fortitude.
Hence,
now,
seems
integration
merely
complementary
but
necessary
one.
By
embracing
medicine,
we
preventive
supportive
survival
rates,
recurrence,
QoL
Financial
sponsorship:
Nil.
Conflicts
interest:
no
conflicts
interest.
