American Journal of Preventive Medicine, Journal Year: 2025, Volume and Issue: 68(4), P. 855 - 856
Published: March 11, 2025
Language: Английский
European Heart Journal, Journal Year: 2025, Volume and Issue: unknown
Published: March 25, 2025
Abstract Background and Aims Blood pressure (BP) is a key modifiable risk factor for atherosclerosis. How BP across different life stages associates with carotid plaque in mid-adulthood remains unclear, which the aim of this study. Methods The sample included 1889 participants from Cardiovascular Risk Young Finns Study who had their measured childhood (6–18 years), young adulthood (21–39 (40–56 years). Outcomes were presence area mid-adulthood. A Bayesian relevant life-course exposure model was used to estimate association determine relative contributions attributed each stage. Results After 38-year follow-up, 745 (39.4%) developed plaques. Cumulative systolic (SBP) childhood, young-, associated [for 1-SD increase (∼12 mm Hg), (95% credible intervals (CrIs)): 1.22 (1.10–1.36)], SBP at stage contributing approximately equally (relative weights: 39.4%; adulthood, 37.9%; mid-adulthood, 22.7%). areas [β CrIs), 0.16 (0.08–0.23)] square millimetre, showing higher contribution 12.5%; 25.0%; 62.5%). Similar patterns observed diastolic BP, pulse pressure, mean arterial pressure. Conclusions contributes presence, greater area. These findings underscore importance maintaining normal throughout reduce atherosclerosis suggest that intensive management may help slow progression.
Language: Английский
Citations
1
JAMA Pediatrics, Journal Year: 2025, Volume and Issue: unknown
Published: March 3, 2025
Language: Английский
Citations
0
JAMA Pediatrics, Journal Year: 2025, Volume and Issue: unknown
Published: March 3, 2025
Language: Английский
Citations
0
American Journal of Preventive Medicine, Journal Year: 2025, Volume and Issue: 68(4), P. 855 - 856
Published: March 11, 2025
Language: Английский
Citations
0