Obstetrics and Gynecology,
Journal Year:
2024,
Volume and Issue:
144(4), P. e101 - e104
Published: Aug. 30, 2024
This
population-based
cross-sectional
study
analyzed
electronic
health
record
data
of
pregnant
individuals
in
an
integrated
care
delivery
system
California
to
examine
changes
prenatal
cannabis
use
through
self-report
and
urine
toxicology
testing
during
standard
between
2012
(n=33,546)
2022
(n=43,415),
test
whether
trends
differed
by
race
ethnicity
or
age.
The
prevalence
increased
from
5.5%
(95%
CI,
5.3–5.8%)
9.0%
8.7–9.2%)
(adjusted
ratio
[aPR]
1.82,
95%
1.72–1.92),
with
similar
increases
(aPR
1.70,
1.60–1.81)
2.12,
1.95–2.30).
increase
varied
significantly
across
racial
ethnic
age
groups,
the
highest
among
Black
those
aged
13–24
years.
Although
rates
more
slowly
groups
use,
disparities
persisted
over
time.
Journal of Addiction Medicine,
Journal Year:
2022,
Volume and Issue:
17(3), P. e192 - e198
Published: Dec. 13, 2022
With
legislative
changes
to
cannabis
legalization
and
increasing
prevalence
of
use,
is
the
most
commonly
used
federally
illicit
drug
in
pregnancy.
Our
study
aims
assess
perinatal
outcomes
associated
with
prenatal
use
disorder.We
conducted
a
retrospective
cohort
using
California
linked
hospital
discharge-vital
statistics
data
included
singleton,
nonanomalous
births
occurring
between
23
42
weeks
gestational
age.
χ2
Test
multivariable
logistic
regression
were
for
statistical
analyses.A
total
2,380,446
patients
included,
9144
(0.38%)
identified
as
during
There
was
significantly
increased
risk
adverse
birthing
person
outcomes,
including
hypertension
(adjusted
odds
ratio
[AOR],
1.19;
95%
confidence
interval
[CI],
1.06-1.34;
P
=
0.004),
preeclampsia
(AOR,
1.16;
CI,
1.0-1.28;
0.006),
preterm
delivery
1.45;
1.35-1.55;
<
0.001),
severe
maternal
morbidity
1.22;
1.02-1.47;
0.033).
Prenatal
disorder
also
an
neonatal
respiratory
distress
syndrome
1.07-1.27;
small
age
1.47;
1.38-1.56;
intensive
care
unit
admission
1.24;
1.16-1.33;
infant
death
1.86;
1.44-2.41;
0.001).
no
statistically
significant
difference
stillbirth
0.96;
0.69-1.34;
0.80)
hypoglycemia
1.00-1.49;
0.045).Our
suggests
that
mortality.
As
pregnancy
becoming
more
prevalent,
our
findings
can
help
guide
preconception
counseling.
Journal of Global Health,
Journal Year:
2025,
Volume and Issue:
15
Published: Feb. 6, 2025
Abstract
Background
A
wide
spectrum
of
high-risk
factors
in
pregnancy
can
lead
to
adverse
outcomes
or
short-
long-term
health
effects.
Despite
this,
there
has
been
no
synthesis
findings
on
the
measurement,
potential
causes,
and
multiple
(MHFP).
We
aimed
address
this
gap
by
summarising
existing
research
topic.
Methods
retrieved
studies
published
up
3
June
2024
through
systematic
database
searches
used
a
narrative
approach
summarise
patterns,
MHFP.
also
estimated
pooled
MHFP
prevalence
meta-analysis
with
random
effects
model
performed
subgroup
analyses
meta-regression
examine
sources
between-study
heterogeneity.
Results
included
83
observational
between
2010
2024,
which
72%
were
from
high-income
countries.
These
studied
be
grouped
into
four
categories:
physical
conditions,
mental
sociobehavioural
problems,
history.
identified
16
among
co-existing
conditions
most
common
pattern.
The
overall
was
12%
(95%
confidence
interval
(CI)
=
12–13),
an
increasing
trend
relatively
higher
levels
low-
middle-income
countries
(LMICs).
observed
heterogeneity
measurement
across
studies,
possibly
due
number
risk
definition
About
78%
investigated
MHFP-associated
for
women
offspring,
only
two
examining
maternal
offspring
later
life.
Conclusions
Research
emerging
over
past
decade,
but
is
far
complete.
burden
worldwide,
particularly
LMICs.
Maternal
healthcare
systems
must
shift
multidisciplinary
integrated
framework
so
as
better
design
implement
prevention
intervention
programmes
sustain
healthy
development
next
generation.
Registration
PROSPERO:
CRD42022358889.
NeoReviews,
Journal Year:
2025,
Volume and Issue:
26(4), P. e247 - e263
Published: April 1, 2025
Cannabis
is
the
most
commonly
used
federally
illicit
substance
during
pregnancy
in
United
States,
with
an
estimated
prevalence
of
3%
to
30%.
The
American
College
Obstetricians
and
Gynecologists
Academy
Pediatrics
discourage
cannabis
use
breastfeeding
due
safety
concerns
for
fetus
infant.
Despite
these
recommendations,
nearly
half
active
users
continue
pregnancy.
In
this
review,
we
summarize
pharmacology
metabolism
a
focus
on
delta-9-tetrahydrocannabinol,
psychoactive
component
plant,
highlighting
its
significance
quantifying
exposure
impact
outcomes
studies.
We
also
provide
concise
review
current
evidence
effects
perinatal
pregnancy,
infant,
childhood
outcomes,
acknowledging
limitations
evidence.
Additionally,
targeted
counseling
recommendations
harm
reduction
strategies
lactation
considerations
birthing
parents
who
cannabis.
Public
perception
contrasts
scientific
findings
on
the
depression-related
effects
of
cannabis.
However,
earlier
studies
were
performed
when
cannabis
was
predominantly
illegal,
its
production
mostly
uncontrolled,
and
idea
medical
incipient
only.
We
hypothesized
that
recent
changes
in
attitudes
legislations
may
have
favorably
affected
research.
In
addition,
publication
bias
against
also
decreased.
To
investigate
this
hypothesis,
we
conducted
a
systematic
review
research
published
over
last
three
years.
found
156
relevant
studies.
most
cross-sectional
studies,
depression
higher
those
who
consumed
than
did
not.
An
increase
consumption
typically
followed
by
an
depression,
whereas
withdrawal
from
ameliorated
cases.
Albeit
reduced
none
these
placebo
controlled.
clinical
same
period,
average
effect
size
larger
investigated
plausibility
antidepressant
reviewing
molecular
pharmacological
Taken
together,
reviewed
do
not
support
herbal