Patient-reported observations on medical procedure timeliness (PROMPT) in breast cancer: a qualitative study

Breast Cancer Research and Treatment, Journal Year: 2024, Volume and Issue: 208(1), P. 123 - 132

Published: July 4, 2024

Language: Английский

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Longitudinal Increases in Time to Surgery for Patients with Breast Cancer: A National Cohort Study

Annals of Surgical Oncology, Journal Year: 2024, Volume and Issue: 31(10), P. 6804 - 6811

Published: July 13, 2024

Abstract Background Longer time to surgery (TTS) is associated with worse survival in patients breast cancer. Whether this association has encouraged more prompt care delivery remains unknown. Methods The National Cancer Database was used identify ≥18 years of age diagnosed clinical stage 0–III cancer between 2006 and 2019 for whom the first mode treatment. A linear-by-linear test trend assessed median TTS across interval. Adjusted linear regression modeling examine trends patient subgroups. Results Overall, 1,435,584 met inclusion criteria. 63 (interquartile range [IQR] 53–72), 84.3% were White, 91.1% non-Hispanic, 99.2% female. 26 days (IQR 16–39) versus 39 27–56) [ p < 0.001]. In a multivariable model, increased significantly, an annual increase 0.83 (95% confidence interval 0.82–0.85; 0.001). consistent, significant observed on subgroup analyses by type, reconstruction, race, hospital disease stage. Black Hispanic ethnicity, having either Medicaid or being uninsured significantly prolonged TTS, as mastectomy reconstructive surgery. Conclusions Despite evidence that longer poorer outcomes cancer, steadily increased, which may be particularly detrimental marginalized patients. Further studies are needed ensure timely all

Language: Английский

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A network dynamic nomogram for predicting overall survival and cancer-specific survival in patients with breast cancer liver metastases: an analysis based on the SEER database

Discover Oncology, Journal Year: 2024, Volume and Issue: 15(1)

Published: Dec. 29, 2024

The liver stands out as one of the most frequent sites for distant metastasis in breast cancer cases. However, effective risk stratification tools patients with metastases (BCLM) are still lacking. We identified BCLM from SEER database spanning 2010 to 2016. After meticulously filtering cases incomplete data, a total 3179 were enrolled and randomly divided into training validation cohorts at ratio 2:1. Leveraging comprehensive patient we constructed nomogram through rigorous evaluation Cox regression model. Validation was conducted using range statistical measures, including concordance index (C-index), calibration curves, time-dependent receiver operating characteristic decision curve analysis (DCA). Both univariable multivariable analyses revealed significant associations between OS CSS 14 variables, age, race, tumor stage, among others. Utilizing these pertinent formulated nomograms prediction. Subsequent involved assessment ROC analysis, C-index evaluations, curves. Our web-based dynamic represents valuable tool efficiently analyzing clinical profiles patients, thereby aiding informed decision-making processes.

Language: Английский

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Delivering on the Fourth Mission Using the National Cancer Database

JAMA Surgery, Journal Year: 2023, Volume and Issue: 158(6), P. 651 - 651

Published: April 12, 2023

Sharon S. Lum, MD, MBA; Amanda E. Browner, MS; Bryan Palis, MA; Heidi Nelson, MD; Daniel Boffa, Leticia M. Nogueira, PhD, MPH; Vicki Hawhee, MEd, CTR; Ryan McCabe, PhD; Timothy Mullett, Elizabeth Wick, MD

Language: Английский

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Invited Commentary: Cancer and COVID: Sailing Uncharted Seas

Journal of the American College of Surgeons, Journal Year: 2023, Volume and Issue: 237(3), P. 430 - 432

Published: June 1, 2023

Language: Английский

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