Methods and Statistical Analysis in a Study of Liver Resection vs Nonsurgical Treatments for Hepatocellular Carcinoma DOI
Jonathan Abdelmalak, John Zalcberg, Stuart K. Roberts

et al.

JAMA Surgery, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 25, 2024

Language: Английский

Bridge Therapy before Liver Transplant for Advanced Hepatocellular Carcinoma DOI Creative Commons
Valentina Bianchi,

Erida Nure,

Carmen Nesci

et al.

Medicina, Journal Year: 2024, Volume and Issue: 60(6), P. 1010 - 1010

Published: June 20, 2024

Hepatocellular carcinoma is the most common primary liver tumor. Orthotopic transplant one of best treatment options, but its waiting list has to be considered. Bridge therapies have been introduced in order limit this issue. The aim study evaluate if bridge advanced hepatocellular can improve overall survival and reduce de-listing. We selected 185 articles. search was limited English articles involving only adult patients. These were deduplicated with incomplete text or irrelevant conclusions excluded. Sorafenib standard care for increases without any significant drug toxicity. However, benefit limited. combination transarterial chemoembolization + sorafenib, instead, delays tumor progression, although still uncertain. A few studies shown that patients undergoing radiation therapy similar even better outcomes than those sorafenib alone rates histopathologic complete response (89% had no residual explant). Also, combined radiotherapy compared association associated a rate (24 vs. 17 months). Moreover, immunotherapy revealed new encouraging perspectives. Combination showed results could become gold as carcinoma.

Language: Английский

Citations

0

Liver resection triumphs: redefining treatment paradigms for early multinodular hepatocellular carcinoma DOI Open Access
Charmy Parikh, Raj H. Patel, Amogh Verma

et al.

International Journal of Surgery Open, Journal Year: 2024, Volume and Issue: 62(4), P. 501 - 502

Published: May 24, 2024

Language: Английский

Citations

0

Methods and Statistical Analysis in a Study of Liver Resection vs Nonsurgical Treatments for Hepatocellular Carcinoma—Reply DOI
Alessandro Vitale, Simone Famularo, Edoardo G. Giannini

et al.

JAMA Surgery, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 25, 2024

Language: Английский

Citations

0

Methods and Statistical Analysis in a Study of Liver Resection vs Nonsurgical Treatments for Hepatocellular Carcinoma DOI
Jonathan Abdelmalak, John Zalcberg, Stuart K. Roberts

et al.

JAMA Surgery, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 25, 2024

Language: Английский

Citations

0