Are fish immunocompetent enough to face climate change?

Biology Letters, Journal Year: 2024, Volume and Issue: 20(2)

Published: Feb. 1, 2024

Ongoing climate change has already been associated with increased disease outbreaks in wild and farmed fish. Here, we evaluate the current knowledge of change-related ecoimmunology teleosts a focus on temperature, hypoxia, salinity acidification before exploring interactive effects multiple stressors. Our literature review reveals that acute chronic changes temperature dissolved oxygen can compromise fish immunity which lead to susceptibility. Moreover, hypoxia have shown enhance infectivity certain pathogens/parasites accelerate progression. Too few studies exist focussed acidification, but direct immune seem be limited while led contrasting results. Likewise, multi-stressor experiments essential for unravelling interactions simultaneously changing environmental factors are still scarce. This ultimately impedes our ability estimate what extent will hamper immunity. about epigenetic regulation mechanisms highlights acclimation potential response environments. However, due number studies, overarching conclusions cannot drawn. Finally, provide an outlook how better realistic scenarios future

Language: Английский

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Age estimation in fishes using epigenetic clocks: Applications to fisheries management and conservation biology

Frontiers in Marine Science, Journal Year: 2023, Volume and Issue: 10

Published: Jan. 30, 2023

The distribution of age classes is a key demographic parameter populations and thus proper estimation crucial for fisheries management conservation biology. Age in fishes has traditionally relied on the analysis growth marks hard structures such as otoliths. However, besides being lethal this method time-consuming, can have low accuracy some species cannot be applied others. Thus, there need development new methods. DNA methylation an epigenetic modification consisting addition methyl group cytosine-guanine loci. Aging associated with changes methylation. Among background global weak genome hypomethylation, are loci which age-associated “clock-like” nature predictable. Chronological estimators built from termed ‘epigenetic clocks’. Epigenetic clocks been developed last ten years many species, notably vertebrates, including already several fish species. Here, we review piscine so far outline major considerations to taken into account additional include number samples collected tissues targeted. steps how develop clock techniques available do also discussed. Next, focus features measuring devices, considering aspects accuracy, precision reproducibility. Finally, discuss possibility developing multi-species processing automation greatly reduce cost per sample. One important knowledge gap determine environmental changes, especially temperature food availability, may affect tick rate clocks. Improved prediction through use contribute better practices context overexploited stocks worldwide, endangered

Language: Английский

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Bioinformatic analysis for age prediction using epigenetic clocks: Application to fisheries management and conservation biology

Frontiers in Marine Science, Journal Year: 2023, Volume and Issue: 10

Published: Feb. 13, 2023

Epigenetic clocks are accurate tools for age prediction and of great interest fisheries management conservation biology. Here, we review the necessary computational steps in order to build an epigenetic clock any species focusing on fish. Currently, a bisulfite conversion method which allows distinction methylated unmethylated cytosines is recommended be performed at single nucleotide resolution. Typically, reduced representation sequencing methods provide enough coverage CpGs select from while exact implemented depends specific objectives cost study. Sequenced reads controlled their quality, aligned either reference or deduced genome methylation levels extracted. Methylation values obtained biological samples fish that cover widest range possible. Using these datasets, machine learning statistical procedures and, particular, penalized regressions, applied identify set combination accurately predict age. Training test datasets used optimal model “epigenetic clock”, can then independent samples. Once robustly identified given species, DNA only small number necessary, thus, efforts including data money resources adjusted interrogate high Implementation this molecular resource routine evaluations population structure expected increase years come due accuracy, robustness decreasing costs sequencing. In context overexploited stocks, as well endangered with easy-to-use much needed improved populations conservation.

Language: Английский

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Development of a Novel Stress and Immune Gene Panel for the Australasian Snapper (Chrysophrys auratus)

Genes, Journal Year: 2024, Volume and Issue: 15(11), P. 1390 - 1390

Published: Oct. 29, 2024

Snapper (

Language: Английский

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Physiological and molecular effects of contaminants of emerging concerns of micro and nano-size in aquatic metazoans: overview and current gaps in Antarctic species

Environmental Science and Pollution Research, Journal Year: 2024, Volume and Issue: 31(36), P. 48888 - 48907

Published: July 27, 2024

Language: Английский

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