Phytochemical Analysis, Antimicrobial, Antibiofilm and Antioxidant Effects of a New Arctic Lichen Placidium Doesaiense Growing in Pakistan
Published: Aug. 30, 2024
Lichenochemical
composition
and
antimicrobial,
antibiofilm
antioxidant
effects
of
a
newly
described
arctic
lichen
Placidium
doesaiense
growing
in
Pakistan
were
investigated.
HPLC–DAD
methods
used
for
identification
secondary
metabolites
acetone
methanol
extracts.
The
total
polyphenol
the
flavonoid
content
was
determined
spectrophotometrically.
study
examined
(DPPH
scavenging
activity
reducing
power),
antibacterial
(minimum
inhibitory
concentration
(MIC)
minimum
bactericidal
(MBC))
(inhibition
biofilm
formation
reduction
mature
biofilm)
activities
extracts
P.
isolated
parietin.
chemical
constituents
olivetol,
olivetolic
acid,
haematommic
fallacinol
parietin,
identified
as
major
compounds
tested
lichen.
Parietin
from
extract
on
separation
column.
had
higher
values
TPC
(21.67
mg
GA/g)
TFC
(377.40
RE/g)
than
extract.
Although
showed
best
(especially
against
Proteus
mirabilis
ATCC
12453),
parietin
demonstrated
superior
Staphylococcus
aureus
25923).
Isolated
measures
according
to
DPPH
(IC50=
51.616
μg/mL)
power.
This
is
first
report
phytochemical
description
some
28
species
genus
Placidia.
research
will
pave
way
further
exploration
new
this
its
metabolites,
which
are
important
medicine
pharmacy.
Language: Английский
Phytochemical Analysis and Antioxidant, Antimicrobial, and Antibiofilm Effects of a New Himalayan Lichen Placidium deosaiense Usman and Khalid Growing in Pakistan
International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(20), P. 11203 - 11203
Published: Oct. 18, 2024
Phytochemical
composition
and
antimicrobial,
antibiofilm,
antioxidant
effects
of
a
newly
described
Himalayan
lichen
Placidium
deosaiense
Usman
Khalid
growing
in
Pakistan
were
investigated.
HPLC–DAD
methods
used
for
identification
secondary
metabolites
acetone
methanol
extracts.
The
total
phenolics
content
was
measured
using
spectrophotometric
method.
study
investigated
the
(DPPH-scavenging
activity
assay
reducing-power
assay),
antibacterial
(minimum
inhibitory
concentration
(MIC)
minimum
bactericidal
(MBC)),
antibiofilm
(inhibition
biofilm
formation
reduction
mature
biofilm)
activities
extracts
P.
isolated
parietin.
chemical
constituents
olivetol,
olivetolic
acid,
haematommic
fallacinol,
parietin
identified
as
major
compounds
tested
lichen.
Parietin
from
extract
on
separation
column.
had
higher
values
TPC
(21.67
mg
GAE/g)
than
extract.
Isolated
showed
best
measures,
according
to
DPPH-scavenging
(IC50
=
51.616
μg/mL)
assay.
Although
(especially
against
Proteus
mirabilis
ATCC
12453),
demonstrated
superior
Staphylococcus
aureus
25923).
This
is
first
report
phytochemical
description
some
45
species
genus
Placidium.
research
will
pave
way
further
exploration
new
this
its
metabolites,
which
are
important
medicine
pharmacy.
Language: Английский