Enhanced and synergistic catalytic activation by photoexcitation driven S−scheme heterojunction hydrogel interface electric field

Nature Communications, Journal Year: 2023, Volume and Issue: 14(1)

Published: Oct. 23, 2023

The regulation of heterogeneous material properties to enhance the peroxymonosulfate (PMS) activation degrade emerging organic pollutants remains a challenge. To solve this problem, we synthesize S-scheme heterojunction PBA/MoS2@chitosan hydrogel achieve photoexcitation synergistic PMS activation. constructed photoexcited carriers undergo redox conversion with through transfer pathway driven by directional interface electric field. Multiple pathways greatly reactive oxygen species generation, leading significant increase in doxycycline degradation rate. Meanwhile, 3D polymer chain spatial structure chitosan is conducive rapid capture and electron transport advanced oxidation process, reducing use transition metal activator limiting leaching ions. There reason believe that regulated will provide new perspective for future design research on enhancing heterologous catalysis process.

Language: Английский

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High-efficiency degradation of carbamazepine by the synergistic electro-activation and bimetals (FeCo@NC) catalytic-activation of peroxymonosulfate

Applied Catalysis B Environment and Energy, Journal Year: 2023, Volume and Issue: 338, P. 123064 - 123064

Published: July 3, 2023

Language: Английский

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Electrospun Janus core (ethyl cellulose//polyethylene oxide) @ shell (hydroxypropyl methyl cellulose acetate succinate) hybrids for an enhanced colon-targeted prolonged drug absorbance

Advanced Composites and Hybrid Materials, Journal Year: 2023, Volume and Issue: 6(6)

Published: Oct. 17, 2023

Language: Английский

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Unraveling the Synergy Mechanism between Photocatalysis and Peroxymonosulfate Activation on a Co/Fe Bimetal-Doped Carbon Nitride

ACS Catalysis, Journal Year: 2023, Volume and Issue: 13(13), P. 8973 - 8986

Published: June 22, 2023

Fenton-like catalysis based on peroxymonosulfate (PMS) activation has shown great potential in the treatment of organic wastewater. Heterogeneous catalysts containing transition metal active sites are highly efficient for PMS activation. However, reduction oxidized was usually not prompt due to sluggish reaction kinetics, which caused insufficient redox cycle and further hampered efficiency. Recent studies have that synergy effect between photocatalysis may address above obstacle boost overall a deeper understanding this is still missing, making it difficult be rationally controlled; thus, poor frequently reported. Herein, Co/Fe bimetal-doped graphitic carbon nitride (g-C3N4) designed representatively through systematical characterization theoretical calculation, revealed profoundly determined by competitive role hole system adsorbed metastable PMS* catalyst surface, furthermore, can manipulated; when doping ratio 2.5:2.5, as-prepared g-C3N4 with moderate valence band position endow an optimized photo-Fenton-like synergistic highest catalytic degradation performance. This work sheds light rational design catalysts.

Language: Английский

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Acceleration of Fe3+/Fe2+ cycle in garland-like MIL-101(Fe)/MoS2 nanosheets to promote peroxymonosulfate activation for sulfamethoxazole degradation

Chemical Engineering Journal, Journal Year: 2023, Volume and Issue: 470, P. 144190 - 144190

Published: June 24, 2023

Language: Английский

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Engineered shapes using electrohydrodynamic atomization for an improved drug delivery

Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology, Journal Year: 2024, Volume and Issue: 16(3)

Published: May 1, 2024

Abstract The shapes of micro‐ and nano‐products have profound influences on their functional performances, which has not received sufficient attention during the past several decades. Electrohydrodynamic atomization (EHDA) techniques, mainly include electrospinning electrospraying, are facile in manipulate products' shapes. In this review, generated using EHDA for modifying drug release profiles reviewed. These linear nanofibers, round micro‐/nano‐particles, beads‐on‐a‐string hybrids. They can be further divided into different kinds sub‐shapes, explored providing desired pulsatile release, sustained biphasic delayed pH‐sensitive release. Additionally, resulted from organizations electrospun nanofibers discussed delivery, inner structures considered together developing novel delivery systems. future, related shape–performance relationships at nanoscale, besides size, structure structure–performance relationships, would play important roles promoting developments field. This article is categorized under: Therapeutic Approaches Drug Discovery > Emerging Technologies

Language: Английский

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Three EHDA Processes from a Detachable Spinneret for Fabricating Drug Fast Dissolution Composites

Macromolecular Materials and Engineering, Journal Year: 2023, Volume and Issue: 309(4)

Published: Nov. 23, 2023

Abstract In this study, three kinds of electrohydrodynamic atomization (EHDA) processes (electrospraying, electrospinning, and coaxial electrospinning) are implemented to create hydroxypropyl methylcellulose (HPMC) based ultra‐thin products for providing the fast dissolution a poorly water‐soluble drug ketoprofen (KET). An EHDA apparatus, characterized by novel spinneret, is homemade conducting processes. The types electrospun nanofibers E1, electrosprayed microparticles E2, core‐shell E3. SEM TEM results indicate that they have anticipated morphologies inner structures. X‐ray diffraction Fourier Transform Infrared verify KET mainly amorphous in all composites due its fine compatibility with HPMC. vitro tests demonstrate rapid release performances has an order E3>E1>E2≫KET powders. mechanisms suggested advantages compared. super performance E3 furnishing attributed synergistic action small size (of shell thickness), high porosity, state drug, solubility nanostructures can support development nano delivery systems (DDSs) through tailoring spatial distribution molecules within products.

Language: Английский

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Tri-Layer Core–Shell Fibers from Coaxial Electrospinning for a Modified Release of Metronidazole

Pharmaceutics, Journal Year: 2023, Volume and Issue: 15(11), P. 2561 - 2561

Published: Oct. 31, 2023

Polymers are the backbone of drug delivery. Electrospinning has greatly enriched strategies that have been explored for developing novel delivery systems using polymers during past two decades. In this study, four different kinds polymers, i.e., water-soluble polymer poly (vinyl alcohol) (PVA), insoluble poly(ε-caprolactone) (PCL), Eudragit RL100 (ERL100) and pH-sensitive S100 (ES100) were successfully converted into types tri-layer tri-polymer core-shell fibers through bi-fluid coaxial electrospinning. During process, model metronidazole (MTD) was loaded shell working fluid, which an emulsion. The micro-formation mechanism from emulsion electrospinning proposed. Scanning electron microscope transmission evaluations verified linear morphology resultant their obvious multiple-chamber structures. X-ray diffraction Fourier transform infrared spectroscopy measurements demonstrated MTD presented in amorphous state compatible with three polymeric matrices. vitro dissolution tests could act a synergistic manner prolonged sustained-release profile gut. controlled-release mechanisms suggested detail. protocols reported here pioneer new route creating structure both aqueous organic solvents, strategy advanced sophisticated profiles.

Language: Английский

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A combined electrohydrodynamic atomization method for preparing nanofiber/microparticle hybrid medicines

Frontiers in Bioengineering and Biotechnology, Journal Year: 2023, Volume and Issue: 11

Published: Nov. 15, 2023

Bacterial prostatitis is a challenging condition to treat with traditional dosage forms. Physicians often prescribe variety of forms different administration methods, which fail provide an efficient and convenient mode drug delivery. The aim this work was develop new type hybrid material incorporating both electrosprayed core-shell microparticles electrospun nanofibers. A Chinese medicine (Ningmitai, NMT) Western (ciprofloxacin, CIP) were co-encapsulated within designed be released in separately controlled manner. Utilizing polyvinylpyrrolidone (PVP) as hydrophilic filament-forming polymer pH-sensitive Eudragit ® S100 (ES100) the particulate polymeric matrix, combined electrohydrodynamic atomization (EHDA) method comprising coaxial electrospraying blending electrospinning, used create hybrids single-step straightforward series characterization methods conducted analyze working process its final products. Scanning electron microscopy transmission revealed that EHDA comprised CIP-PVP nanofibers NMT-ES100 microparticles. Multiple confirmed rapid release CIP sustained NMT. antibacterial experiments indicated exhibited more potent effect against Escherichia coli dh5α Bacillus subtilis Wb800 than either separate or amalgamation fibrous nanomedicine micromedicine can expand horizon types medicines. integration electrospinning provides approach fabrication. By combining soluble polymers hybrids, we ensure sequential NMT for potential synergistic therapy bacterial prostatitis.

Language: Английский

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Shorten migration distance of ROS and accelerate electron transfer by engineering dual Lewis acid sites for synergistic activation of PMS toward rapid TC degradation

Separation and Purification Technology, Journal Year: 2023, Volume and Issue: 330, P. 125244 - 125244

Published: Oct. 28, 2023

Language: Английский

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