Polymer, Journal Year: 2024, Volume and Issue: 315, P. 127823 - 127823
Published: Nov. 13, 2024
Language: Английский
Journal of Functional Biomaterials, Journal Year: 2023, Volume and Issue: 14(7), P. 347 - 347
Published: June 29, 2023
4D printing has emerged as a transformative technology in the field of biomedical engineering, offering potential for dynamic, stimuli-responsive structures with applications tissue drug delivery, medical devices, and diagnostics. This review paper provides comprehensive analysis advancements, challenges, future directions engineering. We discuss development smart materials, including polymers, shape-memory bio-inks, well various fabrication techniques employed, such direct-write assembly, stereolithography, multi-material jetting. Despite promising advances, several challenges persist, material limitations related to biocompatibility, mechanical properties, degradation rates; complexities arising from integration multiple resolution accuracy, scalability; regulatory ethical considerations surrounding safety efficacy. As we explore printing, emphasise need innovations, emerging personalised medicine, nanomedicine, bioelectronic devices. Interdisciplinary research collaboration between science, biology, agencies, industry are essential overcoming realising full engineering landscape.
Language: Английский
Citations
102
Nature Communications, Journal Year: 2024, Volume and Issue: 15(1)
Published: Jan. 26, 2024
Abstract 4D printing technology combines 3D and stimulus-responsive materials, enabling construction of complex objects efficiently. However, unlike smart soft ceramics is a great challenge due to the extremely weak deformability ceramics. Here, we report feasible efficient manufacturing design approach realize direct Photocurable ceramic elastomer slurry hydrogel precursor are developed for fabrication hydrogel-ceramic laminates via multimaterial digital light processing printing. Flat patterned evolve into structures driven by dehydration, then turn pure after sintering. Considering dehydration-induced deformation sintering-induced shape retraction, develop theoretical model calculate curvatures bent laminate sintered part. Then, build flow various objects. This opens new avenue development technology.
Language: Английский
Citations
35
Journal of Colloid and Interface Science, Journal Year: 2024, Volume and Issue: 677, P. 816 - 826
Published: Aug. 16, 2024
Language: Английский
Citations
20
International Journal of Extreme Manufacturing, Journal Year: 2023, Volume and Issue: 6(1), P. 012001 - 012001
Published: Sept. 21, 2023
Abstract Two-photon polymerization (TPP) is a cutting-edge micro/nanoscale three-dimensional (3D) printing technology based on the principle of two-photon absorption. TPP surpasses diffraction limit in achieving feature sizes and excels fabricating intricate 3D micro/nanostructures with exceptional resolution. The concept 4D entails fabrication structures utilizing smart materials capable undergoing shape, property, or functional changes response to external stimuli over time. integration introduces possibility producing responsive accuracy, thereby enhancing capabilities potential applications both technologies. This paper comprehensively reviews TPP-based its diverse applications. First, working principles recent advancements are introduced. Second, optional suitable for discussed. Finally, this review highlights several noteworthy printing, including domains such as biomedical microrobots, bioinspired microactuators, autonomous mobile transformable devices robots, well anti-counterfeiting microdevices. In conclusion, provides valuable insights into current status future prospects technology, serving guide researchers practitioners.
Language: Английский
Citations
37
International Journal of Extreme Manufacturing, Journal Year: 2023, Volume and Issue: 5(4), P. 042012 - 042012
Published: Sept. 7, 2023
Abstract Diverse natural organisms possess stimulus-responsive structures to adapt the surrounding environment. Inspired by nature, researchers have developed various smart with adjustable properties and functions address demands of ever-changing application environments that are becoming more intricate. Among many fabrication methods for structures, femtosecond laser direct writing (FsLDW) has received increasing attention because its high precision, simplicity, true three-dimensional machining ability, wide applicability almost all materials. This paper systematically outlines state-of-the-art research on prepared FsLDW. Based introduction laser-matter interaction mainstream FsLDW-based manufacturing strategies, different stimulating factors can trigger structural responses intelligent such as magnetic field, light, temperature, pH, humidity, emphatically summarized. Various applications functional stimuli-responsive dynamic behaviors fabricated FsLDW, well present obstacles forthcoming development opportunities, discussed.
Language: Английский
Citations
30
Lab on a Chip, Journal Year: 2024, Volume and Issue: 24(9), P. 2371 - 2396
Published: Jan. 1, 2024
Over the past decade, additive manufacturing-or "three-dimensional (3D) printing"-has attracted increasing attention in
Language: Английский
Citations
9
ACS Applied Polymer Materials, Journal Year: 2024, Volume and Issue: unknown
Published: April 24, 2024
Polymer networks are an extensively studied class of materials, a subset which has been developed to respond specific stimuli. These stimuli-responses can be harnessed for enhanced or innovative functionalities, rendering stimuli-responsive polymer network materials highly desired myriad applications ranging from sensing drug delivery. This review provides summary recent progress in design and application including both chemically physically cross-linked networks. Temperature, light, pH, chemical, mechanical, more stimuli discussed the context achieving desirable responses functionalities Furthermore, areas these their various also delved into with particular focus on soft robotics biomedical applications. In addition, computational methodologies introduced as indispensable, complementary strategies experimental characterization analysis further advancement exploration within this domain. Techniques such density functional theory, molecular dynamics simulations, Monte Carlo finite element discussed. Ultimately, insights obtained perspectives chemistry, stimuli, design, methods offer promising trajectory ongoing evolution potential impact field.
Language: Английский
Citations
9
Advanced Materials Technologies, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 11, 2025
Abstract 4D printing combines advancements in 3D with smart materials that change properties response to external stimuli, enabling the fabrication of functional devices directly from printer. Microscale is rapidly growing, driving discovery and applications new strategies. The interest microscale comes its potential propel industrial transformation across different sectors, ranging advanced healthcare cryptography. However, this requires rational design a good understanding material response. This review starts by describing for printing. technologies micrometer resolution their use are then discussed. focus shifts stimuli respond to, mechanism behind obtained shape changes respect applied methods implemented so far realize complex changing behaviors. Examples within sensing, microactuation, data encryption, cargo transport shown. After discussing current challenges mitigation strategies, suggestions on direction field can take given, starting systematic iterative approach developing microstructures.
Language: Английский
Citations
1
Polymers, Journal Year: 2024, Volume and Issue: 16(15), P. 2131 - 2131
Published: July 26, 2024
Conductive hydrogels, known for their flexibility, biocompatibility, and conductivity, have found extensive applications in fields such as healthcare, environmental monitoring, soft robotics. Recent advancements 3D printing technologies transformed the fabrication of conductive creating new opportunities sensing applications. This review provides a comprehensive overview application 3D-printed hydrogel sensors. First, basic principles techniques hydrogels are briefly reviewed. We then explore various methods discussing respective strengths limitations. The also summarizes hydrogel-based In addition, perspectives on sensors highlighted. aims to equip researchers engineers with insights into current landscape inspire future innovations this promising field.
Language: Английский
Citations
5
Advanced Materials Technologies, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 10, 2025
Abstract Although hydrogels are among the most promising materials for a huge variety of biomimicking and tissue engineering applications, conventional such as polydimethylsiloxane (PDMS) still outweigh in terms processability production microfluidic devices. Hence, incorporating hydrogel components inside PDMS‐based chips is approach to take advantage many possibilities utilize hydrogels, while maintaining standard properties devices mechanical stability. Microfluidic produced by soft lithography combined with high‐resolution protein‐based elements fabricated two‐photon polymerization (2PP). Those hybrid used distinguish different cell phenotypes injecting pancreatic cancer cells device investigate interactions microstructures. The Young's modulus blocks printed at experimental conditions determined atomic force microscopy measurements. To showcase high 3D resolution presented fabrication method, fully fibrous meshes configurations microchannels. By measuring velocity circularity that pass through varying densities, impact on flow determined. Furthermore, precursor solution successfully removed immersed phosphate buffered saline.
Language: Английский
Citations
0