Self‐Assembled Metal Complexes in Biomedical Research

Advanced Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 23, 2024

Abstract Cisplatin is widely used in clinical cancer treatment; however, its application often hindered by severe side effects, particularly inherent or acquired resistance of target cells. To address these challenges, an effective strategy to modify the metal core complex and introduce alternative coordination modes valence states, leading development a series complexes, such as platinum (IV) prodrugs cyclometalated complexes. Recent advances nanotechnology have facilitated multifunctional nanomaterials that can selectively deliver drugs tumor cells, thereby overcoming pharmacological limitations metal‐based drugs. This review first explores self‐assembly complexes into spherical, linear, irregular nanoparticles context biomedical applications. The mechanisms underlying are subsequently analyzed, followed discussion their applications fields, including detection, imaging, antitumor research.

Language: Английский

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Chiral Materials for Optics and Electronics: Ready to Rise?

Micromachines, Journal Year: 2024, Volume and Issue: 15(4), P. 528 - 528

Published: April 15, 2024

Chiral materials have gained burgeoning interest in optics and electronics, beyond their classical application field of drug synthesis. In this review, we summarize the diverse chiral developed to date how they been effectively applied electronics get an understanding vision for further development advanced electronics.

Language: Английский

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Ultrafast Laser-Writing of Liquid Crystal Waveguides

Ultrafast Science, Journal Year: 2024, Volume and Issue: 4

Published: Jan. 1, 2024

With the development of conformable photonic platforms, particularly those that could be interfaced with human body or integrated into wearable technology, there is an ever-increasing need for mechanically flexible optical elements in soft materials. Here, we realize liquid crystal (LC) waveguides using a combination ultrafast direct laser writing and ultraviolet (UV) photo-polymerization. Results are presented demonstrate these laser-written can either electrically switchable (by omitting bulk UV polymerization step) flexible. Characteristics waveguide investigated different fabrication conditions geometrical configurations, including dimensions power. Our findings reveal smaller geometries result reduced intensity attenuation. Specifically, 10-μm-wide channel 14-μm-thick LC layer, loss factor −1.8 dB/mm at λ = 650 nm was observed. Following step subsequent delamination glass substrates, free-standing waveguide, which retains functionality even when bent, making it potentially suitable on-skin sensors other devices interface body. For fabricated this study, straight cross-sectional area 20 μm × recorded to −0.2 dB/mm. These results highlight promising potential responsive moldable UV-assisted polymer network formation.

Language: Английский

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Polarization Independent Dynamic Beam Steering based on Liquid Crystal Integrated Metasurface

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Oct. 9, 2024

Digital Micromirror Devices, extensively employed in projection displays offer rapid, polarization-independent beam steering. However, they are constrained by microelectromechanical system limitations, resulting reduced resolution, limited steering angle and poor stability, which hinder further performance optimization. Liquid Crystal on Silicon technology, employing liquid crystal (LC) silicon chip with properties of high contrast good stability. Nevertheless, its polarization-dependent issues lead to complex low efficiency device applications. This paper introduces a hybrid integration metallic metasurface nematic LC, facilitating capable large-angle deflections. Employing principles geometrical phase plasmonic resonances, the metasurface, coupled an electronically controlled allows for dynamic adjustment, achieving maximum deflection ± 27.1°. Additionally, LC-infused dielectric grating modulation polarization conversion ensures uniform effects across all polarizations within device. We verify device's capability insensitivity effect simulations propose optimization scheme cope individual diffraction stages.

Language: Английский

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Self-Oscillation of Liquid Crystal Elastomer Fiber-Slide System Driven by Self-Flickering Light Source

Polymers, Journal Year: 2024, Volume and Issue: 16(23), P. 3298 - 3298

Published: Nov. 26, 2024

Self-oscillation, a control approach inspired by biological systems, demonstrates an autonomous, continuous, and regular response to constant external environmental stimuli. Until now, most self-oscillation systems have relied on static environment that continuously supplies energy, while materials typically absorb ambient energy only intermittently. In this article, we propose innovative of liquid crystal elastomer (LCE) fiber-slide system driven self-flickering light source, which can efficiently regulate the input in sync with self-oscillating behavior under voltage. This primarily consists photo-responsive LCE fiber, slider includes conductive segment insulating segment, track. Using dynamic model, derive governing equation for motion fiber-slider system. Numerical simulations show voltage exhibits two distinct phases, namely stationary phase phase. The occurs due photo-induced contraction fiber when source is activated. We also investigate critical conditions required initiate self-oscillation, examine key parameters influencing its frequency amplitude. Unlike continuous release from field our dynamically adjusts synchronize behavior. Our design features advantages such as spontaneous periodic lighting, simple structure, efficiency, ease operation. It shows significant promise circuit monitoring devices, optical applications.

Language: Английский

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