Tongue Prick Bionic Angularly Adjustable Microneedles for Enhanced Scarless Wound Healing

Advanced Functional Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 15, 2025

Abstract High‐tension site wounds are frequently accompanied by challenges associated with hypertrophic scarring. The key to achieving scar‐free healing is the creation of a mechanical environment conducive skin regeneration. Herein, simple rolling punctures utilized on angle transform molds develop cat tongue prick bionic angle‐adjustable microneedles (TPMNs) maintain firm grip periwound skin, thereby reducing tissue tension. integration TPMNs triboelectric nanogenerators (TENGs) enables excellent conductive and properties. system can provide stable spatial electric field around wound promote cell migration. As microfluid reaches TPMNs, self‐driving force enhanced unique design control flow rate. Sufficient evidence has shown that expedite contraction regeneration while concurrently scar formation in mouse trauma model experiments. innovative TPMNs‐TENGs synergistically provides highly functional platform for tension relief, which suitable treatment this study potentially extends construction regulation smart wearable devices.

Language: Английский

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Microneedles based on hyaluronic acid-polyvinyl alcohol with antibacterial, anti-inflammatory, and antioxidant effects promote diabetic wound healing

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 282, P. 137185 - 137185

Published: Nov. 1, 2024

Language: Английский

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Recent progress in the 3D printing of microneedle patches for biomedical applications

International Journal of Pharmaceutics, Journal Year: 2024, Volume and Issue: unknown, P. 124995 - 124995

Published: Nov. 1, 2024

Language: Английский

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Recent advances in iontophoresis-assisted microneedle devices for transdermal biosensing and drug delivery

Materials Today Bio, Journal Year: 2025, Volume and Issue: 31, P. 101504 - 101504

Published: Jan. 19, 2025

Integrating advanced manufacturing techniques and nanotechnology with cutting-edge materials has driven significant progress in global healthcare. Microneedles, recognized for their minimally invasive approach to transdermal sensing drug delivery, achieve enhanced functionality when combined iontophoresis. Iontophoresis-assisted microneedles have emerged as an innovative solution, enabling real-time biosensing precise delivery within closed-loop systems. These integrated platforms represent a major advancement personalized medicine, allowing dynamic therapeutic adjustments based on continuous feedback. This review highlights the latest developments iontophoresis-assisted biosensing, applications. It delves into mechanisms of iontophoresis, assesses its advantages limitations, explores future directions these transformative technologies.

Language: Английский

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Fabrication strategies and microscale sensing functionalities of mechanochromic colloidal photonic crystals for underwater applications

Microstructures, Journal Year: 2025, Volume and Issue: 5(1)

Published: Jan. 25, 2025

Mechanochromic colloidal photonic crystals (PCs), which typically integrate a self-assembled PC array with highly elastic medium, exhibit the ability to reversibly respond external mechanical stimuli by altering periodicity of structures. Nowadays, leveraging visible indications and optical signals for forces, mechanochromic PCs have been widely used in reflecting body motion, health monitoring, communications daily life. However, despite their extensive applications on land, it is vital explore potential sensing underwater, where message transmission mainly relies gestures motions. This review comprehensively examines recent advancements underwater applications. The first part introduces response mechanism PCs, emphasizing main principles that facilitate microscale. second describes fabrication strategies constructing these demonstrating various approaches establish sensors specific functionalities. final section discusses confronted challenges summarizes opportunities developing

Language: Английский

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Recombinant human nerve growth factor Integrated hyaluronic acid hydrogel microneedles for corneal nerve repairing

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 160344 - 160344

Published: Feb. 1, 2025

Language: Английский

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γ-polyglutamic acid-encapsulated metformin-loaded Ga-Car-MOF and hydrocaffeic acid-modified chitosan double-layer microneedle patch for accelerated bacterial-infected wound healing

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 304, P. 140959 - 140959

Published: Feb. 12, 2025

Language: Английский

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3D-printed microneedles for sensing applications: emerging topics and future trends

Advanced Sensor and Energy Materials, Journal Year: 2025, Volume and Issue: unknown, P. 100139 - 100139

Published: Feb. 1, 2025

Language: Английский

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Multi-level DLD microfluidic chip for plasma separation: A novel approach using Cu-ACE

Results in Physics, Journal Year: 2025, Volume and Issue: unknown, P. 108209 - 108209

Published: March 1, 2025

Language: Английский

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Towards injured joints rehabilitation: structural color hydrogels for accelerated wound healing and rehabilitation exercises monitoring

Journal of Materials Chemistry B, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

A structural color hydrogel composed of a hybrid double-network is developed for accelerated wound healing and rehabilitation exercise monitoring.

Language: Английский

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