Application of Nanomaterials in the Diagnosis and Treatment of Retinal Diseases DOI

Yufei Yao,

Qiannan Cao,

Huapan Fang

et al.

Small, Journal Year: 2025, Volume and Issue: unknown

Published: April 8, 2025

Abstract In recent years, nanomaterials have demonstrated broad prospects in the diagnosis and treatment of retinal diseases due to their unique physicochemical properties, such as small‐size effects, high biocompatibility, functional surfaces. Retinal are often accompanied by complex pathological microenvironments, where conventional diagnostic therapeutic approaches face challenges low drug delivery efficiency, risks associated with invasive procedures, difficulties real‐time monitoring. Nanomaterials hold promise addressing these limitations traditional therapies, thereby improving precision efficacy. The applications diagnostics summarized, they enable high‐resolution imaging carrying fluorescent probes or contrast agents act biosensors sensitively detect disease‐related biomarkers, facilitating early dynamic therapeutics, functionalized nanocarriers can precisely deliver drugs, genes, antioxidant molecules target cells, significantly enhancing outcomes while reducing systemic toxicity. Additionally, nanofiber materials possess properties that make them particularly suitable for regeneration tissue engineering. By loading neurotrophic factors into scaffolds, regenerative effects be amplified, promoting repair neurons. Despite immense potential, clinical translation still requires long‐term biosafety, scalable manufacturing processes, optimization targeting efficiency.

Language: Английский

Application of Nanomaterials in the Diagnosis and Treatment of Retinal Diseases DOI

Yufei Yao,

Qiannan Cao,

Huapan Fang

et al.

Small, Journal Year: 2025, Volume and Issue: unknown

Published: April 8, 2025

Abstract In recent years, nanomaterials have demonstrated broad prospects in the diagnosis and treatment of retinal diseases due to their unique physicochemical properties, such as small‐size effects, high biocompatibility, functional surfaces. Retinal are often accompanied by complex pathological microenvironments, where conventional diagnostic therapeutic approaches face challenges low drug delivery efficiency, risks associated with invasive procedures, difficulties real‐time monitoring. Nanomaterials hold promise addressing these limitations traditional therapies, thereby improving precision efficacy. The applications diagnostics summarized, they enable high‐resolution imaging carrying fluorescent probes or contrast agents act biosensors sensitively detect disease‐related biomarkers, facilitating early dynamic therapeutics, functionalized nanocarriers can precisely deliver drugs, genes, antioxidant molecules target cells, significantly enhancing outcomes while reducing systemic toxicity. Additionally, nanofiber materials possess properties that make them particularly suitable for regeneration tissue engineering. By loading neurotrophic factors into scaffolds, regenerative effects be amplified, promoting repair neurons. Despite immense potential, clinical translation still requires long‐term biosafety, scalable manufacturing processes, optimization targeting efficiency.

Language: Английский

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