Enhanced healing of MRSA-infected wounds with okara cellulose nanocrystals-based temperature-sensitive cationic hydrogel: Development and characterization DOI
Lu Tang, Bo Wang,

Shiru Bai

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 139087 - 139087

Published: Dec. 1, 2024

Language: Английский

Recent Advances on In Situ Tissue Adhesives DOI Creative Commons
Jing Yu, Yuxuan Yang, Jin Zhu

et al.

Fundamental Research, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

Citations

1

Sustained release of migrasomes from a methacrylate-oxidized hyaluronic acid/methacrylated gelatin composite hydrogel accelerates skin wound healing DOI
Haoyu Zhou, Shiqiang Zhang, Jingjiang Qiu

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 141355 - 141355

Published: Feb. 1, 2025

Language: Английский

Citations

0

Starfish-Inspired Synergistic Reinforced Hydrogel Wound Dressing: Dual Responsiveness and Enhanced Bioactive Compound Delivery for Advanced Skin Regeneration and Management DOI

Gonghua Hong,

Jiawen Li,

Wenqi Wei

et al.

ACS Nano, Journal Year: 2025, Volume and Issue: unknown

Published: March 6, 2025

Effective wound management demands advanced dressings that protect while actively supporting healing. Traditional often fall short of meeting the complex needs skin repair. Inspired by regenerative abilities starfish, we developed a bionically engineered hydrogel designed to enhance The is synthesized through coassembly dopamine-modified cellulose nanofibers, chitosan, (3-aminobenzeneboronic acid)-grafted oxidized dextran, and poly(vinyl alcohol), utilizing dynamic Schiff base boronic ester linkages. This innovative design imparts multifunctional properties, including injectability, 3D printability, antibacterial activity, self-adhesion, self-healing, antioxidant protection, hemostasis, which emulate defense mechanisms processes starfish. These characteristics work synergistically reduce infection oxidative stress improve healing efficiency. Additionally, incorporates mangiferin Vitamin C, are released in controlled manner response wound's microenvironment (pH reactive oxygen species), promoting tissue regeneration reducing inflammation. In vitro tests confirmed its dual responsiveness, finite element modeling validated release bioactive compounds. vivo testing on rat full-thickness model showed 100% rate day 13, significantly outperforming commercial alternatives. hydrogel's nontoxicity capabilities make it promising solution for patients with critical needs, offering comprehensive integration natural biological cutting-edge engineering.

Language: Английский

Citations

0

Anti-Inflammatory Mechanisms of Acca sellowiana Peel in RAW264.7 Cells: Involvement of the JAK-STAT Signaling Pathway DOI
Shanshan Li,

Penghui Ou,

Xiaona Zhang

et al.

ACS Food Science & Technology, Journal Year: 2025, Volume and Issue: unknown

Published: March 19, 2025

Language: Английский

Citations

0

Robust Injectable Hydrogels for Hemophilic Arthropathy via Anti‐Inflammation, Iron Removal and Cartilage Protection DOI
Jianhua Zhang,

Jian Zhong,

Bo Liang

et al.

Advanced Functional Materials, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Abstract Hemophilic arthropathy (HA), a form of arthritis associated with joint bleeding, presents extra challenges in treatment due to intermittent bleeding‐induced iron‐overloading, oxidative stress, and inflammation. Conventional therapeutic approaches have predominantly concentrated on achieving hemostasis reducing inflammation, yet they fallen short effectively managing iron overload safeguarding cartilage, resulting less‐than‐ideal outcomes. To address these issues, series injectable hydrogels is facilely fabricated via one‐step assembly polyphenols, chelators, lipoic acid. In vitro investigations demonstrate that the not only good performances antioxidation anti‐inflammation, but also exhibit promising prospects removal, adhesion resistance, wear resistance. Moreover, vivo studies are further carried out indicate diminished inflammatory response, ameliorative iron‐overload‐related lesion indicators, cartilage preservation. This class robust multifunctional composed clinically available drugs along commonly used commercial ingredients would offer new opportunities toward efficient HA.

Language: Английский

Citations

0

Light‐Driven PAA Adhesive: A Green Bonding Platform Integrating High‐Performance, Environmental Resilience, and Closed‐Loop Recyclability DOI Creative Commons

Xueying Fu,

Jingtian Chen,

Yuqi Zhao

et al.

Advanced Science, Journal Year: 2025, Volume and Issue: unknown

Published: April 25, 2025

Abstract The increasing demand for environmentally benign materials has driven significant interest in water‐based adhesives due to their low toxicity and ecological advantages. However, conventional formulations face persistent challenges including limited bonding strength, complex manufacturing processes, compromised storage stability. To address these limitations, a polyacrylic acid‐based aqueous adhesive (PAA) is developed through novel visible‐light catalytic platform. This approach ensures mild cycle, thereby promoting sustained strategic integration of hydrogen bonding, electrostatic interactions, mechanical interlocking enhances interfacial adhesion. Notably, the demonstrates an adhesion strength up 20.86 MPa on wood 12.91 bamboo substrates. Its composition confers stability across diverse environmental conditions, extreme temperature variations (−196 °C–200 °C), prolonged (> 270 days), resistance stress solvent exposure. Furthermore, PAA exhibits full recyclability water‐mediated dissociation recovery process. study represents pioneering application catalysis synthesis, advancing development sustainable high‐performance systems.

Language: Английский

Citations

0

Tannic Acid Film Based on One-Dimensional Supramolecular Self-Assembly for Electrical Conductivity and Oil–Water Separation DOI
Jie Yang, Fulin Yang, Can Liu

et al.

ACS Applied Materials & Interfaces, Journal Year: 2024, Volume and Issue: 16(42), P. 57596 - 57602

Published: Oct. 8, 2024

Tannic acid is widely regarded as one of the most promising natural polyphenolic compounds. However, current research predominantly focuses on utilization its phenolic hydroxyl groups, with limited exploration functional potential aromatic structure. Herein, one-dimensional nanofibers based supramolecular self-assembly were successfully prepared through simple alkylation reaction tannic and π–π stacking structures. These fibers, lengths reaching tens micrometers an average height 10 nm, clearly observed using SEM AFM. A film excellent electrical conductivity (σ = 37.9 μS/cm) was fabricated by vacuum filtering organic suspension these which 100-fold higher than that TA film. Additionally, hydrophobic lipophilic properties Bn-TA further investigated oil–water separation experiments, where membrane displayed efficiency durability, maintaining stable performance over multiple cycles. This strategy presents opportunities for high-value acid.

Language: Английский

Citations

1

Enhanced healing of MRSA-infected wounds with okara cellulose nanocrystals-based temperature-sensitive cationic hydrogel: Development and characterization DOI
Lu Tang, Bo Wang,

Shiru Bai

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 139087 - 139087

Published: Dec. 1, 2024

Language: Английский

Citations

0