Multifunctional nanofiber system with photothermal-controlled drug delivery and motion monitoring capabilities as intelligent wound dressing DOI

Peiran Lin,

K. K. He,

Jiahui Luo

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 503, P. 158544 - 158544

Published: Dec. 11, 2024

Language: Английский

Review of light activated antibacterial nanomaterials in the second biological window DOI Creative Commons
Suresh Thangudu, Chia‐Hao Su

Journal of Nanobiotechnology, Journal Year: 2025, Volume and Issue: 23(1)

Published: April 15, 2025

Language: Английский

Citations

0
Dynamic multistage nanozyme hydrogel reprograms diabetic wound microenvironment: synergistic oxidative stress alleviation and mitochondrial restoration DOI Creative Commons
Jingyu Yan, Yifan Zhao,

Chenying Cui

et al.

Materials Today Bio, Journal Year: 2025, Volume and Issue: 32, P. 101780 - 101780

Published: April 17, 2025

Chronic diabetic wounds remain a significant clinical challenge due to persistent bacterial infections, oxidative stress, impaired angiogenesis, and mitochondrial dysfunction. Traditional therapies often fail address these interrelated pathological factors, highlighting the urgent need for innovative solutions. Here, we present Mn-ZIF@GOx/BC (MZGB) hydrogel system, where Mn-ZIF@GOx (MZG) nanozymes are successfully integrated into cellulose (BC) via hydrogen bonding electrostatic interactions. The MZGB lowers wound pH by oxidizing excess glucose gluconic acid. It exhibits strong ROS scavenging capabilities through its superoxide dismutase catalase-like activities, while simultaneously providing oxygen. By restoring redox homeostasis, it protects function enhances cellular energy metabolism. reprogramming macrophages, creates favorable immune microenvironment, significantly promoting angiogenesis paracrine mechanisms. This facilitates cell-to-cell communication, forming positive feedback loop. Moreover, demonstrates ROS-independent antibacterial properties. BC ensures adhesion moisture regulation, protective barrier maintaining an optimal environment. multifunctional represents promising nanotherapeutic approach efficiently treating precisely regulating microenvironment.

Language: Английский

Citations

0
Multifunctional nanofiber system with photothermal-controlled drug delivery and motion monitoring capabilities as intelligent wound dressing DOI

Peiran Lin,

K. K. He,

Jiahui Luo

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 503, P. 158544 - 158544

Published: Dec. 11, 2024

Language: Английский

Citations

1