Macromolecular Rapid Communications, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 14, 2025
Abstract Hemiacetal esters are versatile functional groups known for their unique ability to degrade under mild conditions such as exposure water, alcohols, organic acids, or heat. In this study, hemiacetal introduced mild, transient protecting carboxylic acids along polycarbonate backbones. A six‐membered cyclic carbonate monomer is synthesized by reacting ethyl vinyl ether with a acid precursor, demonstrating high efficiency and stability nucleophilic polymerization conditions. Potential susceptibilities of the transacetalization reactions do not occur these Instead, well‐defined homo PEG‐based block copolymers obtained narrow molecular weight distributions preserved ester functionalities. These labile side chain enabled facile deprotection, yielding polycarbonates free holding significant potential applications in drug delivery, sustainable polymers, advanced materials.
Language: Английский