Construction of a Multifunctional Janus Nanofiber Membrane Based on Tannic Acid–Fe Complexes for Photothermal/Drug Synergistic Antibacteria DOI
Xuefei Chen, Xiaohu Ren, Yì Wáng

et al.

ACS Applied Polymer Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 5, 2024

Language: Английский

Dual Oxygen Supply System of Carbon Dot-Loaded Microbubbles with Acoustic Cavitation for Enhanced Sonodynamic Therapy in Diabetic Wound Healing DOI

Guangrong Ma,

Ke Cheng, Xue Wang

et al.

Biomaterials, Journal Year: 2025, Volume and Issue: unknown, P. 123145 - 123145

Published: Jan. 1, 2025

Language: Английский

Citations

1
Tailoring Versatile Nanoheterojunction-Incorporated Hydrogel Dressing for Wound Bacterial Biofilm Infection Theranostics DOI

Shuting Zhang,

Wenxuan He, Jian‐Wen Dong

et al.

ACS Nano, Journal Year: 2025, Volume and Issue: unknown

Published: March 12, 2025

Wound-infected bacterial biofilms are protected by self-secreted extracellular polymer substances (EPS), which can confer them with formidable resistance to the host's immune responses and antibiotics, thus delays in diagnosis treatment cause stubborn infections life-threatening complications. However, tailoring an integrated theranostic platform capability promptly diagnose treat wound biofilm infection still remains a challenge. Herein, versatile erbium-doped carbon dot-encapsulated zeolitic imidazolate framework-8 (Er:CDs@ZIF-8) nanoheterojunction (C@Z nano-HJ) is tailored incorporated into gelatin methacrylate/poly(N-hydroxyethyl acrylamide) (GelMA/PHEAA)-based tough sticky hydrogel dressing (GH-C@Z) achieve infection-integrated application. Stimulated acidic microenvironment of biofilm, turn-on response C@Z assists monitoring exhibiting cyan fluorescence. Meanwhile, effectively destroy EPS barrier accomplish photothermal-photodynamic-ion interference synergistic antibacterial therapy under near-infrared light. Furthermore, after effective eradication potent antioxidant properties released Er:CDs allow attenuate reactive oxygen species mitigate inflammatory responses, finally promote collagen deposition neovascularization accelerate healing. Overall, this provides insight development diagnostic therapeutic platforms for infections.

Language: Английский

Citations

1
Engineered Microneedle System Enables the Smart Regulation of Nanodynamic Sterilization and Tissue Regeneration for Wound Management DOI Creative Commons
Shiyang Lin, Zhongqi Cui,

Qingqiong Luo

et al.

Advanced Science, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 13, 2025

Abstract The healing of bacterial biofilm‐infected wounds is a complex process, and the construction emerging therapeutic modalities that regulate microenvironment to magnify effects reduce biotoxicity still highly challenging. Herein, an engineered microneedle (MN) patch reported mediate efficient delivery black phosphorus nanosheets (BP NSs) copper peroxide nanodots (CP NDs) for dual nanodynamic sterilization methicillin‐resistant staphylococcus aureus (MRSA)‐infected wound healing. Results demonstrate system can eliminate biofilm, cytotoxicity, promote angiogenesis tissue regeneration by multiple advantages chemodynamic therapy (CDT), enhanced photodynamic (PDT), improved degradation process from BP NSs phosphate promoting cell proliferation. Notably, balance between excellent stability rapid degradability maintained, mechanism vividly elucidated density functional theory (DFT)‐based molecular dynamics (MD) calculations. Furthermore, transcriptional changes treated MRSA‐infected skin are studied using RNA‐seq technology reveal potential mechanism. As envisaged, proposed MN provides safe, easy, also effective approach achieve temporal regulation wounds.

Language: Английский

Citations

0
Vacancies-Rich Z-Scheme VdW Heterojunction as H2S-Sensitized Synergistic Therapeutic Nanoplatform against Refractory Biofilm Infections DOI

Jufang Dong,

Shuting Zhang,

Yau Kei Chan

et al.

Biomaterials, Journal Year: 2025, Volume and Issue: 320, P. 123258 - 123258

Published: March 13, 2025

Language: Английский

Citations

0
GO-aptamer hydrogel microneedle sensors for the on-site detection of exosomes in interstitial fluid on acupuncture treatment DOI
Jiachen Shen,

Wenjuan Fu,

Wei Wei

et al.

Biosensors and Bioelectronics, Journal Year: 2025, Volume and Issue: unknown, P. 117426 - 117426

Published: March 1, 2025

Language: Английский

Citations

0
Operando Surface Ligands Boost Pt Nanozyme Activity for H2O2 Catalysis via Bridged Electron Transfer DOI
Shuangshuang Wei, Wentao Zhang, Ziyi Wang

et al.

ACS Catalysis, Journal Year: 2025, Volume and Issue: unknown, P. 6439 - 6449

Published: April 4, 2025

Language: Английский

Citations

0
Microneedle-aided nanotherapeutics delivery and nanosensor intervention in advanced tissue regeneration DOI Creative Commons

Churong Xu,

Fei Wu,

Zhouyi Duan

et al.

Journal of Nanobiotechnology, Journal Year: 2025, Volume and Issue: 23(1)

Published: May 3, 2025

Language: Английский

Citations

0
Multifunctional nanocomposite-driven microneedles enabling bacteria capturing, detecting, and killing for precision treatment of acne with varying severities DOI
Huaan Li, Hanqi Li,

Yuwei Kou

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 163339 - 163339

Published: May 1, 2025

Language: Английский

Citations

0
Construction of a Multifunctional Janus Nanofiber Membrane Based on Tannic Acid–Fe Complexes for Photothermal/Drug Synergistic Antibacteria DOI
Xuefei Chen, Xiaohu Ren, Yì Wáng

et al.

ACS Applied Polymer Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 5, 2024

Language: Английский

Citations

1