Carbon, Journal Year: 2020, Volume and Issue: 161, P. 784 - 793
Published: Feb. 4, 2020
Language: Английский
Carbon, Journal Year: 2020, Volume and Issue: 161, P. 784 - 793
Published: Feb. 4, 2020
Language: Английский
Drug Discovery Today, Journal Year: 2018, Volume and Issue: 23(7), P. 1436 - 1443
Published: May 20, 2018
Language: Английский
Citations
126Topics in Current Chemistry, Journal Year: 2020, Volume and Issue: 378(1)
Published: Jan. 14, 2020
Language: Английский
Citations
126Biomaterials, Journal Year: 2019, Volume and Issue: 207, P. 89 - 101
Published: March 21, 2019
Language: Английский
Citations
117Advanced Healthcare Materials, Journal Year: 2019, Volume and Issue: 8(14)
Published: April 15, 2019
Abstract Engineering biocompatible hydrogels using functional nanoparticles has attracted considerable attention because of their uniquely appealing cooperative effects that can enable multimodality imaging and treatment with improved efficacy against serious diseases. However, the high‐content nanoparticle dopants on rheological properties frequently lead to an unsatisfactory therapeutic result, which is particularly notable in design magnetic hydrogel formulations for cancer therapy. Herein reported a novel functionalized by ferromagnetic vortex‐domain iron oxide (FVIOs) optimally adaptive functions prevention breast recurrence. The FVIOs perfectly incorporate into dynamic networks extremely low concentration (0.6 mg mL −1 ), 17 times lower than conventional superparamagnetic sufficient heating capacity. Such exhibit high inductive remarkable simultaneously. Moreover, self‐healing, self‐conformal ability, controlled release loaded doxorubicin, biodegradation, pH‐responsiveness project efficient sustainable ability. In vivo postoperative further demonstrated FVIO‐based hydrogels, as evidenced significant suppression local tumor recurrences compared chemotherapy or hyperthermia alone. This unique formulation shows strong potential preventing relapses various cancers.
Language: Английский
Citations
113Carbon, Journal Year: 2020, Volume and Issue: 161, P. 784 - 793
Published: Feb. 4, 2020
Language: Английский
Citations
111