Microchemical Journal, Journal Year: 2023, Volume and Issue: 197, P. 109727 - 109727
Published: Nov. 28, 2023
Language: Английский
Microchemical Journal, Journal Year: 2023, Volume and Issue: 197, P. 109727 - 109727
Published: Nov. 28, 2023
Language: Английский
Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 489, P. 151215 - 151215
Published: April 10, 2024
Language: Английский
Citations
2PAMM, Journal Year: 2024, Volume and Issue: 24(2)
Published: Aug. 1, 2024
Abstract Stimuli‐responsive hydrogels are representatives of smart materials with enormous swelling capability. The prediction discrete hydrogel states by artificial neural network based on the processing parameters has been realized in our previous work. In current study, we explore ways to enhance capabilities integrating physical information curves model: Instead predicting states, predict mathematical continuous curve. We therefore assume that behavior is consistent a sigmoidal tanh function, their properties. After function trained model, analyze accuracy comparison initial prediction. Moreover, new approach then allows us physically interpret different material properties, which denote sensitivity, maximum achievable differential swelling, and position reference point for derivation model.
Language: Английский
Citations
2Science Advances, Journal Year: 2024, Volume and Issue: 10(36)
Published: Sept. 6, 2024
Functional assays on intact tumor biopsies can complement genomics-based approaches for precision oncology, drug testing, and organs-on-chips cancer disease models by capturing key therapeutic response determinants, such as tissue architecture, heterogeneity, the microenvironment. Most of these rely fluorescent labeling, a semiquantitative method best suited single-time-point or labor-intensive immunostaining analysis. Here, we report integrated aptamer electrochemical sensors on-chip, real-time monitoring cytochrome C, cell death indicator, from microdissected tissues with high affinity specificity. The platform features multi-well sensor layout multiplexed electronic setup. aptasensors measure increases in C supernatant mouse human tumors after exposure to various treatments. Because sensor’s affinity, it primarily tracks rising concentrations dynamic changes during apoptosis. This approach could help develop more advanced apply other complex vitro models, organoids.
Language: Английский
Citations
2Composites Part A Applied Science and Manufacturing, Journal Year: 2023, Volume and Issue: 175, P. 107814 - 107814
Published: Sept. 29, 2023
Language: Английский
Citations
6Microchemical Journal, Journal Year: 2023, Volume and Issue: 197, P. 109727 - 109727
Published: Nov. 28, 2023
Language: Английский
Citations
6