The utilization of metal-organic frameworks in tumor-targeted drug delivery systems DOI Creative Commons
Jiahui Kong, Mengru Cai,

Rongyue Zhu

et al.

Journal of Science Advanced Materials and Devices, Journal Year: 2024, Volume and Issue: 9(3), P. 100770 - 100770

Published: July 23, 2024

Due to the non-specific distribution of drugs in body and low concentration at tumor site traditional chemotherapy, there are challenges associated with significant side effects resistance. Therefore, a drug delivery system (DDS) urgently needs be developed that can precisely target tumors. Metal-organic frameworks (MOFs) possess advantageous characteristics derived from organic inorganic materials, including small particle size, large specific surface area, high loading capacity, adjustable structure pore as well ease modification. Consequently, MOFs offer unique advantages for designing active targeting, passive stimulus-responsive targeting strategies have become hot topic current research on tumor-targeted systems. This review will elaborate application systems perspective different strategies. We hope this paper provide assistance therapy.

Language: Английский

Prospects, advances and biological applications of MOF-based platform for the treatment of lung cancer DOI

Yijun Deng,

Manli Guo,

Luyi Zhou

et al.

Biomaterials Science, Journal Year: 2024, Volume and Issue: 12(15), P. 3725 - 3744

Published: Jan. 1, 2024

Herein, we reviewed the recent development in use of MOF materials as a platform for treatment lung cancer.

Language: Английский

Citations

55

Functional modification engineering of metal–organic frameworks for the contaminants detection in food DOI

Xingxue Zhang,

Tao Huang,

Yuqing Gao

et al.

Coordination Chemistry Reviews, Journal Year: 2024, Volume and Issue: 516, P. 215990 - 215990

Published: May 31, 2024

Language: Английский

Citations

53

Biomedical application of metal-organic frameworks (MOFs) in cancer therapy: Stimuli-responsive and biomimetic nanocomposites in targeted delivery, phototherapy and diagnosis DOI

Beixu Li,

Milad Ashrafizadeh,

Taiwei Jiao

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 260, P. 129391 - 129391

Published: Jan. 20, 2024

Language: Английский

Citations

47

Metal-organic framework-based dressings: Application and opportunities in wound healing DOI

Qianying Huang,

Ying Chen,

Min Ye

et al.

Materials Today Chemistry, Journal Year: 2024, Volume and Issue: 40, P. 102235 - 102235

Published: Aug. 20, 2024

Language: Английский

Citations

42

MOFs and MOF‐Based Composites as Next‐Generation Materials for Wound Healing and Dressings DOI Creative Commons
Ashkan Bigham,

Negar Islami,

Arezoo Khosravi

et al.

Small, Journal Year: 2024, Volume and Issue: 20(30)

Published: March 7, 2024

Abstract In recent years, there has been growing interest in developing innovative materials and therapeutic strategies to enhance wound healing outcomes, especially for chronic wounds antimicrobial resistance. Metal–organic frameworks (MOFs) represent a promising class of next‐generation dressings. Their high surface area, pore structures, stimuli‐responsiveness, antibacterial properties, biocompatibility, potential combination therapies make them suitable complex care challenges. MOF‐based composites promote cell proliferation, angiogenesis, matrix synthesis, acting as carriers bioactive molecules promoting tissue regeneration. They also have stimuli‐responsivity, enabling photothermal skin cancer infections. Herein, critical analysis the current state research on MOFs dressings is provided, offering valuable insights into applications, challenges, future directions this field. This literature review targeted multifunctionality nature wound‐disease therapy from different aspects discussed most advancements made context, reader will find how contributed field yield more effective, functional, they lead next generation biomaterials

Language: Английский

Citations

36

Covalent-Metal organic Frameworks: Preparation and applications DOI
Zhaobo Wang, Chen Wang, Qiming Hu

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 483, P. 149217 - 149217

Published: Feb. 2, 2024

Language: Английский

Citations

18

Current status and prospects of MIL-based MOF materials for biomedicine applications DOI

Zengqin Lin,

Donghui Liao,

Chenyi Jiang

et al.

RSC Medicinal Chemistry, Journal Year: 2023, Volume and Issue: 14(10), P. 1914 - 1933

Published: Jan. 1, 2023

This review focuses on drug delivery systems based MIL-100(Fe) and MIL-101(Fe) that have made significant progress in chemodynamic therapy, photothermal photodynamic combined therapy.

Language: Английский

Citations

32

Multifunctional nano MOF drug delivery platform in combination therapy DOI

Dongwei Ma,

Gang Wang, Jing-Sheng Lu

et al.

European Journal of Medicinal Chemistry, Journal Year: 2023, Volume and Issue: 261, P. 115884 - 115884

Published: Oct. 16, 2023

Language: Английский

Citations

30

Current status and prospect of ZIF-based materials for breast cancer treatment DOI

Yana Zeng,

Donghui Liao,

Xiangyang Kong

et al.

Colloids and Surfaces B Biointerfaces, Journal Year: 2023, Volume and Issue: 232, P. 113612 - 113612

Published: Oct. 26, 2023

Language: Английский

Citations

28

A new Ag‐based photocatalyst for efficient degradation of antibiotic nitrofurantoin DOI
Yichen Liu,

Changxin Zhou,

Ruifang Xiang

et al.

Applied Organometallic Chemistry, Journal Year: 2024, Volume and Issue: 38(7)

Published: May 15, 2024

In this paper, a new 0D Ag(I)‐based coordination polymer [Ag 2 (dib)(H L) ]( 1 ) is proposed as photocatalyst for the photocatalytic degradation of nitrofurantoin (NFT) under ultraviolet irradiation. The catalytic was analyzed by various methods such PXRD, SEM, FT‐IR, TGA, UV–vis, DRS, and electrochemical tests. experimental result shows that an n ‐type semiconductor, which can effectively catalyze photodegradation NFT Under optimal reaction conditions, rate 97.95% within 60 min when concentration 30 ppm. experiment free radical capture O ˙ − main active substance photodecomposition, possible mechanism proposed. This research will lay foundation polymers in field antibiotic degradation.

Language: Английский

Citations

15