Cancers,
Journal Year:
2024,
Volume and Issue:
16(23), P. 4085 - 4085
Published: Dec. 5, 2024
Medical
devices
used
for
functional
or
esthetic
purposes
improve
health
and
quality
of
life;
however,
they
are
not
risk-free.
Anaplastic
large-cell
lymphoma
(ALCL),
associated
with
breast
implants,
is
a
well-known
recognized
distinct
entity.
More
recently,
additional
lymphomas
have
been
reported
in
relation
to
prosthesis
other
than
as
these
allow
the
pericyte
develop
into
clone
that
undergoes
maturation
process,
progressing
toward
full
malignancy.
Heliyon,
Journal Year:
2024,
Volume and Issue:
10(16), P. e35836 - e35836
Published: Aug. 1, 2024
Stem
cell
transplantation
has
emerged
as
a
promising
avenue
in
regenerative
medicine,
potentially
facilitating
tissue
repair
degenerative
diseases
and
injuries.
This
review
comprehensively
examines
recent
developments
challenges
stem
transplantation.
It
explores
the
identification
isolation
of
various
types,
including
embryonic,
induced
pluripotent,
adult
cells
derived
from
multiple
sources.
Additionally,
highlights
tissue-specific
applications
these
cells,
focusing
on
bone
cartilage
regeneration,
treatment
neurological
disorders,
management
hematological
conditions.
Future
advancements
effective
resolution
current
will
be
crucial
fully
realizing
potential
medicine.
With
responsible
ethical
practices,
field
can
transform
disease
injury
treatment,
ultimately
improving
quality
life
for
countless
individuals.
Biomaterials Research,
Journal Year:
2025,
Volume and Issue:
29
Published: Jan. 1, 2025
Tendon/ligament-bone
junctions
(T/LBJs)
are
susceptible
to
damage
during
exercise,
resulting
in
anterior
cruciate
ligament
rupture
or
rotator
cuff
tear;
however,
their
intricate
hierarchical
structure
hinders
self-regeneration.
Multiphasic
strategies
have
been
explored
fuel
heterogeneous
tissue
regeneration
and
integration.
This
review
summarizes
current
multiphasic
approaches
for
rejuvenating
functional
gradients
T/LBJ
healing.
Synthetic,
natural,
organism-derived
materials
available
vivo
validation.
Both
discrete
gradient
layouts
serve
as
sources
of
inspiration
organizing
specific
cues,
based
on
the
theories
biomaterial
topology,
biochemistry,
mechanobiology,
situ
delivery
therapy,
which
form
interconnected
network
within
design.
Novel
engineering
can
be
constructed
by
electrospinning,
3-dimensional
printing,
bioprinting,
textiling,
other
techniques.
Despite
these
efforts
being
limited
at
present
stage,
scaffolds
show
great
potential
precise
reproduction
native
T/LBJs
offer
promising
solutions
clinical
dilemmas.
Polymers,
Journal Year:
2025,
Volume and Issue:
17(7), P. 886 - 886
Published: March 26, 2025
Three-dimensional
(3D)
printing
is
a
cutting-edge
technology
that
widely
used
in
biomedical
fields
to
construct
various
commercial
products
or
scaffolds
for
theoretical
research.
In
this
review,
3D
technologies
with
different
principles
are
briefly
introduced,
including
selective
laser
melting
(SLM),
sintering
(SLS),
fused
deposition
modeling
(FDM),
stereolithography
(SLA),
and
digital
light
processing
(DLP).
addition,
the
applications
of
dentistry,
such
as
dental
implantology,
prosthodontics,
orthodontics,
maxillofacial
surgery,
tissue
regeneration,
were
summarized.
Furthermore,
perspective
challenges
also
addressed
help
readers
obtain
clear
map
development
dentistry.
Coatings,
Journal Year:
2025,
Volume and Issue:
15(4), P. 416 - 416
Published: April 1, 2025
Bone
tissue
is
intrinsically
electroactive,
and
electrical
signaling
one
of
its
key
regulatory
mechanisms.
The
electroactive
poly
(vinylidene
fluoride
trifluoroethylene)
(PVTF),
due
to
piezoelectricity,
can
provide
stimulation
cells,
regulating
their
proliferation
osteogenic
differentiation.
Collagen
I
(COL)
the
main
organic
component
bone
involved
in
various
physiological
processes
bone.
A
crucial
question
that
remains
be
explored
whether
materials
meet
requirements
for
GBR
membranes
what
synergistic
effects
signals
collagen’s
biochemical
might
have
on
cellular
behavior.
In
this
study,
PVTF/COL
composite
films
were
prepared
using
polydopamine
(PDA).
It
was
found
collagen
modification
could
increase
surface
Kelvin
potential
PVTF
from
−5.07
V
2.22
V,
reduce
WCA
98.9°
33.2°,
maintain
tensile
strength
at
24.94
MPa.
Additionally,
film
significantly
promoted
adhesion
marrow
stem
cells
(BMSCs),
ALP
activity
PPC3
after
7
days
5.6
times
higher
than
P
films.
This
study
presents
a
novel
effective
approach
explores
applications
GBR.
BME Frontiers,
Journal Year:
2024,
Volume and Issue:
6
Published: Dec. 27, 2024
Objective:
This
study
aims
to
clarify
the
effects
of
bioceramic
interface
cues
on
macrophages.
Impact
Statement:
Recently,
there
have
been
many
researches
exploring
topography
macrophage
polarization
and
cytokine
secretion.
However,
underlying
mechanisms
macrophages
still
need
exploring.
provides
insights
into
micro-groove
surface
structures
Introduction:
With
development
bone
tissue
engineering
methods,
bioceramics
used
for
repair.
After
implantation
bioceramics,
innate
immune
response
that
occurs
at
materials
can
deeply
influence
subsequent
inflammation
regeneration
progress.
Therefore,
exploration
regulation
will
be
beneficial
promote
effects.
Methods:
In
this
study,
with
are
fabricated
by
digital
light
processing
3-dimensional
printing
technology.
Then,
different
spacings
(0,
25,
50,
75
μm)
prepared
separately
explore
Results:
The
large
spacing
structure
M2
osteoinductive
secretion
macrophage.
reason
is
induce
directional
arrangement
so
as
change
phenotype
Further
show
osteogenic
differentiation
mesenchymal
stem
cells,
which
benefit
osteogenesis
osteointegration.
Conclusion:
offers
an
effective
application
potential
method
Small Science,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 17, 2024
Modulating
macrophage
phenotype
based
on
implant
surface
characteristics,
including
topography
and
chemistry,
has
been
employed
to
enhance
osseointegration
long‐term
functional
outcomes
for
titanium
(Ti)‐based
implants.
An
excessive
and/or
prolonged
M1
response
can
lead
damaging
immune‐inflammatory
reactions,
negatively
influencing
the
fate
of
implant,
hence,
modulating
these
responses
via
nanoscale
modification
is
an
emerging
paradigm.
Herein,
anodized
single‐step
electrochemical
anodization,
with
preserved
underlying
microfeatures
superimposed
nanopores
(50
70
nm),
compared
irregular
rough
microrough
(machined‐like)
surfaces,
investigated
its
effect
functions
primary
macrophages
in
vitro.
Significantly
reduced
proliferation
increased
tissue‐reparative
M2
polarization
are
confirmed
nanopores,
which
more
pronounced
nm
diameter.
Moreover,
osteoclastogenesis
while
osteogenic
differentiation
osteoblasts
enhanced
(higher
pores).
Advanced
nanoengineered
Ti
implants
tissue
integration
by
inflammatory
at
implant–cell
interface.