Emerging Non-Breast Implant-Associated Lymphomas: A Systematic Review DOI Open Access
Arianna Di Napoli,

Santo Fruscione,

Sergio Mazzola

et al.

Cancers, Journal Year: 2024, Volume and Issue: 16(23), P. 4085 - 4085

Published: Dec. 5, 2024

Medical devices used for functional or esthetic purposes improve health and quality of life; however, they are not risk-free. Anaplastic large-cell lymphoma (ALCL), associated with breast implants, is a well-known recognized distinct entity. More recently, additional lymphomas have been reported in relation to prosthesis other than as these allow the pericyte develop into clone that undergoes maturation process, progressing toward full malignancy.

Language: Английский

Advancements and Challenges in Stem Cell Transplantation for Regenerative Medicine DOI Creative Commons

Lingxi Wei,

Wenqi Yan,

Wahid Shah

et al.

Heliyon, Journal Year: 2024, Volume and Issue: 10(16), P. e35836 - e35836

Published: Aug. 1, 2024

Stem cell transplantation has emerged as a promising avenue in regenerative medicine, potentially facilitating tissue repair degenerative diseases and injuries. This review comprehensively examines recent developments challenges stem transplantation. It explores the identification isolation of various types, including embryonic, induced pluripotent, adult cells derived from multiple sources. Additionally, highlights tissue-specific applications these cells, focusing on bone cartilage regeneration, treatment neurological disorders, management hematological conditions. Future advancements effective resolution current will be crucial fully realizing potential medicine. With responsible ethical practices, field can transform disease injury treatment, ultimately improving quality life for countless individuals.

Language: Английский

Citations

9

Hierarchy Reproduction: Multiphasic Strategies for Tendon/ligament-bone Junctions Repair DOI Creative Commons
Kaiting Chen, Zezheng Liu, Xinying Zhou

et al.

Biomaterials Research, Journal Year: 2025, Volume and Issue: 29

Published: Jan. 1, 2025

Tendon/ligament-bone junctions (T/LBJs) are susceptible to damage during exercise, resulting in anterior cruciate ligament rupture or rotator cuff tear; however, their intricate hierarchical structure hinders self-regeneration. Multiphasic strategies have been explored fuel heterogeneous tissue regeneration and integration. This review summarizes current multiphasic approaches for rejuvenating functional gradients T/LBJ healing. Synthetic, natural, organism-derived materials available vivo validation. Both discrete gradient layouts serve as sources of inspiration organizing specific cues, based on the theories biomaterial topology, biochemistry, mechanobiology, situ delivery therapy, which form interconnected network within design. Novel engineering can be constructed by electrospinning, 3-dimensional printing, bioprinting, textiling, other techniques. Despite these efforts being limited at present stage, scaffolds show great potential precise reproduction native T/LBJs offer promising solutions clinical dilemmas.

Language: Английский

Citations

1

Formation and biological activities of foreign body giant cells in response to biomaterials DOI

Fangyuan Cai,

Bulin Jiang,

Fuming He

et al.

Acta Biomaterialia, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 1, 2024

Language: Английский

Citations

5

Application of 3D Printing Technology in Dentistry: A Review DOI Open Access

Yangqing Chen,

Junchao Wei

Polymers, Journal Year: 2025, Volume and Issue: 17(7), P. 886 - 886

Published: March 26, 2025

Three-dimensional (3D) printing is a cutting-edge technology that widely used in biomedical fields to construct various commercial products or scaffolds for theoretical research. In this review, 3D technologies with different principles are briefly introduced, including selective laser melting (SLM), sintering (SLS), fused deposition modeling (FDM), stereolithography (SLA), and digital light processing (DLP). addition, the applications of dentistry, such as dental implantology, prosthodontics, orthodontics, maxillofacial surgery, tissue regeneration, were summarized. Furthermore, perspective challenges also addressed help readers obtain clear map development dentistry.

Language: Английский

Citations

0

Fabrication of PVTF/COL Composite Films and Its Impact on Osteogenic Differentiation DOI Open Access

Haoqing Liu,

Chengwei Wu, Weimin Lin

et al.

Coatings, Journal Year: 2025, Volume and Issue: 15(4), P. 416 - 416

Published: April 1, 2025

Bone tissue is intrinsically electroactive, and electrical signaling one of its key regulatory mechanisms. The electroactive poly (vinylidene fluoride trifluoroethylene) (PVTF), due to piezoelectricity, can provide stimulation cells, regulating their proliferation osteogenic differentiation. Collagen I (COL) the main organic component bone involved in various physiological processes bone. A crucial question that remains be explored whether materials meet requirements for GBR membranes what synergistic effects signals collagen’s biochemical might have on cellular behavior. In this study, PVTF/COL composite films were prepared using polydopamine (PDA). It was found collagen modification could increase surface Kelvin potential PVTF from −5.07 V 2.22 V, reduce WCA 98.9° 33.2°, maintain tensile strength at 24.94 MPa. Additionally, film significantly promoted adhesion marrow stem cells (BMSCs), ALP activity PPC3 after 7 days 5.6 times higher than P films. This study presents a novel effective approach explores applications GBR.

Language: Английский

Citations

0

Macrophage response to fibrin structure mediated by Tgm2-dependent mitochondrial mechanosensing DOI

Bicong Gao,

Haifeng Ni,

Junhong Lai

et al.

Bioactive Materials, Journal Year: 2025, Volume and Issue: 50, P. 382 - 395

Published: April 22, 2025

Language: Английский

Citations

0

Smart nanomaterials for multimodal theranostics and tissue regeneration DOI
Hyun Lee, Kyoung Sub Kim, Iman Zare

et al.

Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 541, P. 216801 - 216801

Published: May 17, 2025

Language: Английский

Citations

0

Bioceramic surface topography regulating immune osteogenesis DOI Creative Commons

Jianxin Hao,

Lin Du,

Yu He

et al.

BME Frontiers, Journal Year: 2024, Volume and Issue: 6

Published: Dec. 27, 2024

Objective: This study aims to clarify the effects of bioceramic interface cues on macrophages. Impact Statement: Recently, there have been many researches exploring topography macrophage polarization and cytokine secretion. However, underlying mechanisms macrophages still need exploring. provides insights into micro-groove surface structures Introduction: With development bone tissue engineering methods, bioceramics used for repair. After implantation bioceramics, innate immune response that occurs at materials can deeply influence subsequent inflammation regeneration progress. Therefore, exploration regulation will be beneficial promote effects. Methods: In this study, with are fabricated by digital light processing 3-dimensional printing technology. Then, different spacings (0, 25, 50, 75 μm) prepared separately explore Results: The large spacing structure M2 osteoinductive secretion macrophage. reason is induce directional arrangement so as change phenotype Further show osteogenic differentiation mesenchymal stem cells, which benefit osteogenesis osteointegration. Conclusion: offers an effective application potential method

Language: Английский

Citations

3

Stiffness and Surface Topology of Silicone Implants Competitively Mediate Inflammatory Responses of Macrophages and Foreign Body Response DOI Creative Commons
Shuchang He, Qingrong Zhang,

Jiezhi Jia

et al.

Materials Today Bio, Journal Year: 2024, Volume and Issue: 29, P. 101304 - 101304

Published: Oct. 18, 2024

Language: Английский

Citations

2

Inflammatory or Reparative? Tuning Macrophage Polarization Using Anodized Anisotropic Nanoporous Titanium Implant Surfaces DOI Creative Commons
Ho‐Jin Moon, Karan Gulati, Tao Li

et al.

Small Science, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 17, 2024

Modulating macrophage phenotype based on implant surface characteristics, including topography and chemistry, has been employed to enhance osseointegration long‐term functional outcomes for titanium (Ti)‐based implants. An excessive and/or prolonged M1 response can lead damaging immune‐inflammatory reactions, negatively influencing the fate of implant, hence, modulating these responses via nanoscale modification is an emerging paradigm. Herein, anodized single‐step electrochemical anodization, with preserved underlying microfeatures superimposed nanopores (50 70 nm), compared irregular rough microrough (machined‐like) surfaces, investigated its effect functions primary macrophages in vitro. Significantly reduced proliferation increased tissue‐reparative M2 polarization are confirmed nanopores, which more pronounced nm diameter. Moreover, osteoclastogenesis while osteogenic differentiation osteoblasts enhanced (higher pores). Advanced nanoengineered Ti implants tissue integration by inflammatory at implant–cell interface.

Language: Английский

Citations

1