Biomacromolecules,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 17, 2025
The
skin
is
fragile,
making
it
very
vulnerable
to
damage
and
injury.
Untreated
wounds
can
pose
a
serious
threat
human
health.
Three-dimensional
polymer
network
hydrogels
have
broad
application
prospects
in
wound
dressings
due
their
unique
properties
structure.
therapeutic
effect
of
traditional
limited,
while
multifunctional
composite
show
greater
potential.
Multifunctional
regulate
moisture
through
formula
adjustment.
Moreover,
be
combined
with
bioactive
ingredients
improve
performance
healing
applications.
Stimulus-responsive
respond
specifically
the
environment
meet
needs
different
stages.
This
review
summarizes
material
types,
structure,
properties,
design
considerations,
formulation
strategies
for
hydrogel
used
healing.
We
discuss
various
types
recently
developed
dressings,
highlights
importance
tailoring
physicochemical
addresses
potential
challenges
preparing
dressings.
Advanced Functional Materials,
Journal Year:
2024,
Volume and Issue:
unknown
Published: May 11, 2024
Abstract
The
continuously
growing
utilization
of
wound
healing
materials
and
skin
bioelectronics
urges
the
development
flexible
hydrogels
for
personal
therapy
health
management.
Versatile
conductive
prepared
from
natural
biomass
are
ideal
candidates
as
one
promising
solutions
chronic
Here,
study
proposes
a
kind
robust
(strain:
1560.8%),
adhesive,
self‐healing,
injectable,
antibacterial
(sterilization
rate:
99%),
near‐infrared
(NIR)
photothermal
responsive,
biocompatible,
hydrogel
(CPPFe@TA)
composed
carboxymethyl
cellulose
tannic
acid/iron
ion
complex
(TA@Fe
3+
),
featuring
rapid
self‐assembly
tunable
crosslinking
time.
TA@Fe
facilitated
self‐catalysis
polymerization
reaction,
time
could
be
controlled
by
adjusting
Fe
concentration.
Under
NIR
irradiation,
exhibited
remarkable
performance.
In
full‐thickness
defect
repair
experiment
on
mice,
dressing
significantly
enhanced
healing.
After
14
days,
rate
(95.49%)
CPPFe@TA3
+
treatment
greatly
exceeded
that
commercial
dressings.
Meanwhile,
has
good
electrical
conductivity
thermo‐responsiveness,
making
them
in
physiological
signal
monitoring
rehabilitation
exercise
This
work
therefore
offers
strategy
developing
versatile
biomass‐based
hydrogels,
which
is
expected
to
applicable
integrated
regenerative
bioelectronics.
Gels,
Journal Year:
2025,
Volume and Issue:
11(4), P. 258 - 258
Published: April 1, 2025
Conductive
hydrogels,
integrating
high
conductivity,
mechanical
flexibility,
and
biocompatibility,
have
emerged
as
crucial
materials
driving
the
evolution
of
next-generation
wearable
sensors.
Their
unique
ability
to
establish
seamless
interfaces
with
biological
tissues
enables
real-time
acquisition
physiological
signals,
external
stimuli,
even
therapeutic
feedback,
paving
way
for
intelligent
health
monitoring
personalized
medical
interventions.
To
fully
harness
their
potential,
significant
efforts
been
dedicated
tailoring
conductive
networks,
properties,
environmental
stability
these
hydrogels
through
rational
design
systematic
optimization.
This
review
comprehensively
summarizes
strategies
categorized
into
metal-based,
carbon-based,
polymer-based,
ionic,
hybrid
systems.
For
each
type,
highlights
structural
principles,
conductivity
enhancement,
approaches
simultaneously
enhance
robustness
long-term
under
complex
environments.
Furthermore,
emerging
applications
in
sensing
systems
are
thoroughly
discussed,
covering
signal
monitoring,
mechano-responsive
platforms,
closed-loop
diagnostic–therapeutic
Finally,
this
identifies
key
challenges
offers
future
perspectives
guide
development
multifunctional,
intelligent,
scalable
hydrogel
sensors,
accelerating
translation
advanced
flexible
electronics
smart
healthcare
technologies.
Gels,
Journal Year:
2024,
Volume and Issue:
10(4), P. 241 - 241
Published: April 1, 2024
This
manuscript
explores
self-healing
hydrogels
as
innovative
solutions
for
diverse
wound
management
challenges.
Addressing
antibiotic
resistance
and
tailored
care,
these
exhibit
promising
outcomes,
including
accelerated
closure
tissue
regeneration.
Advancements
in
multifunctional
with
controlled
drug
release,
antimicrobial
properties,
real-time
assessment
capabilities
signal
a
significant
leap
toward
patient-centered
treatments.
However,
challenges
such
scalability,
long-term
safety
evaluation,
variability
clinical
outcomes
persist.
Future
directions
emphasize
personalized
medicine,
manufacturing
innovation,
rigorous
evaluation
through
trials,
interdisciplinary
collaboration.
features
the
ongoing
pursuit
of
effective,
adaptable,
comprehensive
care
to
transform
medical
treatments
improve
patient
outcomes.
