Nanozyme-Based Strategies in Cancer Immunotherapy: Overcoming Resistance to Enhance Therapeutic Efficacy DOI Creative Commons
Guangjian Hou, Yukun Xu, Chunhua Wang

et al.

Aging and Disease, Journal Year: 2025, Volume and Issue: unknown, P. 0 - 0

Published: Jan. 1, 2025

Nanozymes, which are nanomaterials that replicate the catalytic activities of natural enzymes in biological systems, have recently demonstrated considerable potential improving cancer immunotherapy by altering tumor microenvironment. Nanozyme-driven immune responses represent an innovative therapeutic modality with high effectiveness and minimal side effects. These nanozymes activate system to specifically recognize destroy cells. Combined immunotherapeutic agents, can amplify anti-cancer integrating remodeling immunogenic cell death (ICD). This review offers a thorough discussion about various involved immunity, including those mimicking catalase (CAT), superoxide dismutase (SOD), peroxidase (POD), oxidase (OXD). It also discusses challenges future directions for translating nanozyme platforms into clinical applications, enhancing susceptibility cells immunotherapy. Nanozyme-based strategies substantial oncology, offering new effective options management.

Language: Английский

Micro/nano system-mediated local treatment in conjunction with immune checkpoint inhibitor against advanced-Stage malignant melanoma DOI
Lu Tang, Hening Liu, Yue Yin

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 497, P. 154499 - 154499

Published: Aug. 3, 2024

Language: Английский

Citations

4
Advances and Future Trends in Nanozyme-Based SERS Sensors for Food Safety, Environmental and Biomedical Applications DOI Open Access
Xingyu Wang, Xuemei Tang,

Chengzhen Ji

et al.

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(2), P. 709 - 709

Published: Jan. 15, 2025

Nanozymes, a kind of nanoparticles with enzyme-mimicking activities, have attracted considerable attention due to their robust catalytic properties, ease preparation, and resistance harsh conditions. By combining nanozymes surface-enhanced Raman spectroscopy (SERS) technology, highly sensitive selective sensors been developed. These are capable detecting wide range analytes, such as foodborne toxins, environmental pollutants, biomedical markers. This review provides an overview recent advancements in the synthesis surface modification nanozymes, highlighting ability mimic multiple enzymes enhance performance. In addition, we explore development applications nanozyme-based SERS food contaminants, The concludes perspectives challenges facing field, involving need for deeper understanding nanozyme principles mechanisms, standardized systems characterization, engineering tailored properties specific applications. Finally, discuss potential integrating various techniques create multi-modal detection platforms, paving way next generation analytical tools fields safety, monitoring, diagnostics.

Language: Английский

Citations

0
Microneedle-based nanodrugs for tumor immunotherapy DOI

Tianye Wang,

Hongyu Liu, Meng Li

et al.

Journal of Controlled Release, Journal Year: 2025, Volume and Issue: 380, P. 539 - 562

Published: Feb. 13, 2025

Language: Английский

Citations

0
Nanozyme-Based Strategies in Cancer Immunotherapy: Overcoming Resistance to Enhance Therapeutic Efficacy DOI Creative Commons
Guangjian Hou, Yukun Xu, Chunhua Wang

et al.

Aging and Disease, Journal Year: 2025, Volume and Issue: unknown, P. 0 - 0

Published: Jan. 1, 2025

Nanozymes, which are nanomaterials that replicate the catalytic activities of natural enzymes in biological systems, have recently demonstrated considerable potential improving cancer immunotherapy by altering tumor microenvironment. Nanozyme-driven immune responses represent an innovative therapeutic modality with high effectiveness and minimal side effects. These nanozymes activate system to specifically recognize destroy cells. Combined immunotherapeutic agents, can amplify anti-cancer integrating remodeling immunogenic cell death (ICD). This review offers a thorough discussion about various involved immunity, including those mimicking catalase (CAT), superoxide dismutase (SOD), peroxidase (POD), oxidase (OXD). It also discusses challenges future directions for translating nanozyme platforms into clinical applications, enhancing susceptibility cells immunotherapy. Nanozyme-based strategies substantial oncology, offering new effective options management.

Language: Английский

Citations

0