Computational Fluid Dynamics (CFD) Analysis of 3D Printer Nozzle Designs DOI Open Access

Rasul Hajili,

Mikail Temirel

Bitlis Eren Üniversitesi Fen Bilimleri Dergisi, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 29, 2024

Additive manufacturing, particularly 3D printing, has garnered significant attention recently due to its flexibility, precision, and sustainability. Fused Deposition Modeling (FDM)-based printers are among the most popular in field their low cost, practical usage, print quality. However, one of major disadvantages these is quality or resolution. The factor affecting nozzle design, including geometry. Thus, many works literature have focused on enhancing printing quality, especially which a substantial impact performance. In this study, effects geometry three aspects were investigated with computational fluid dynamics (CFD) perspective: die angle, outlet’s size shape. CFD results show that angle primarily affects shear stresses developed nozzle, predominantly impacts velocity pressure difference, shape stress, velocity, difference lesser extent compared size.

Language: Английский

Process Optimization for Coaxial Extrusion-Based Bioprinting: A Comprehensive Analysis of Material Behavior, Structural Precision, and Cell Viability DOI

Jiarun Sun,

Youping Gong,

Yuchen He

et al.

Additive manufacturing, Journal Year: 2025, Volume and Issue: unknown, P. 104682 - 104682

Published: Jan. 1, 2025

Language: Английский

Citations

1
Optimizing enzymatic bioreactors: The role of mass transfer in enhancing catalytic efficiency and stability DOI
Dan Wang, Hao Zhang, Yukun Wang

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: 508, P. 160844 - 160844

Published: Feb. 26, 2025

Language: Английский

Citations

1
Biomechanical and mechanobiological design for bioprinting functional microvasculature DOI
Dongrui Zhang, J. Liu, Xiao Liu

et al.

Applied Physics Reviews, Journal Year: 2025, Volume and Issue: 12(1)

Published: March 1, 2025

Functional microvasculature is essential for in vitro tissue constructs, ensuring efficient transport of oxygen, nutrients, and waste supporting vital paracrine signaling stability. Recent advancements both direct indirect 3D bioprinting offer promising solutions to construct complex vascular networks by allowing precise control over cell extracellular matrix placement. The process from shape printing function formation involves dynamic shift bioink mechanical properties, microenvironments, mechanobiology endothelial cells. This review explores how biomechanical mechanobiological principles are integrated into the develop functional microvascular networks. Before printing, a top-level design approach based on these focuses interactions among biomaterials, behaviors, environments guide network fabrication. During bioinks different techniques, along with optimized factors process, ensures accurate structure reproduction while maintaining viability. After emphasis creating suitable environment modulate multiple steps neovascularization, including initiation, morphogenesis, lumen formation, stabilization, maturation microvasculature. Finally, we discuss future developments drive functionalized

Language: Английский

Citations

0
Design and Performance Analysis of Spiral Microchannels for Efficient Particle Separation Using Inertial Microfluidics DOI Creative Commons
Eda Özyilmaz, Gamze Gediz İliş

Micromachines, Journal Year: 2025, Volume and Issue: 16(3), P. 349 - 349

Published: March 19, 2025

Accurate separation in microfluidic devices is crucial for biomedical applications; however, enhancing their performance remains challenging due to computational and experimental constraints. This study aims optimize by systematically refining spiral microchannel configurations the segregation of circulating tumor cells (CTCs) red blood (RBCs) through detailed variable analysis resource-efficient techniques. The design was developed into six variations, considering loop numbers (2, 3, 4), aspect ratios (2.333, 3.333, 5), radii (5, 6, 7 mm), flow rates (1.5, 2, 3 mL/min), surface roughness levels (0, 0.5, 1 μm), particle sizes (12, 18, 24 μm). Simulations were conducted COMSOL Multiphysics evaluated using Taguchi method determine optimal configuration, reducing set from 216 27 an efficient approach. results identified structure as having ratio four loops, a radius 6–7 mm, rate mL/min, μm, diameter μm. Among parameters, (61.2%) had most significant impact, followed number loops (13.9%) (9.4%). optimized demonstrated high efficiency purity, achieving 97.5% 97.6%, respectively. fabrication process involved 3D-printing channel mold, polydimethylsiloxane (PDMS) casting, validating durability scalability proposed design. integrates simulation results, providing robust framework developing next-generation advancing diagnostic targeted therapeutic applications.

Language: Английский

Citations

0
Optimising Bioprinting Nozzles through Computational Modelling and Design of Experiments DOI Creative Commons
J. Carlos Gómez-Blanco, A. Macı́as-Garcı́a, Jesús M. Rodríguez-Rego

et al.

Biomimetics, Journal Year: 2024, Volume and Issue: 9(8), P. 460 - 460

Published: July 29, 2024

3D bioprinting is a promising technique for creating artificial tissues and organs. One of the main challenges cell damage, due to high pressures tensions. During biofabrication process, extrusion usually results in low viability, typically ranging from 40% 80%, although better printing performance with higher viability can be achieved by optimising experimental design operating conditions, nozzle geometry being key factor. This article presents review studies that have used computational fluid dynamics (CFD) optimise geometry. They show optimal ranges diameter length are 0.2 mm 1 8 10 mm, respectively. In addition, it recommended should an internal angle 20 30 degrees, coating ethylenediaminetetraacetic acid (EDTA), shear stress less than kPa. experiments obtain configuration bioink also presented. would identify conditions minimise damage improve printed cells.

Language: Английский

Citations

1
Two-dimensional parametric investigation of zinc-air fuel cell with flowing electrolyte by numerical method DOI
Minh‐Khoa Nguyen, K. David Huang

Electrochimica Acta, Journal Year: 2024, Volume and Issue: unknown, P. 145548 - 145548

Published: Dec. 1, 2024

Language: Английский

Citations

0
Computational Fluid Dynamics (CFD) Analysis of 3D Printer Nozzle Designs DOI Open Access

Rasul Hajili,

Mikail Temirel

Bitlis Eren Üniversitesi Fen Bilimleri Dergisi, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 29, 2024

Additive manufacturing, particularly 3D printing, has garnered significant attention recently due to its flexibility, precision, and sustainability. Fused Deposition Modeling (FDM)-based printers are among the most popular in field their low cost, practical usage, print quality. However, one of major disadvantages these is quality or resolution. The factor affecting nozzle design, including geometry. Thus, many works literature have focused on enhancing printing quality, especially which a substantial impact performance. In this study, effects geometry three aspects were investigated with computational fluid dynamics (CFD) perspective: die angle, outlet’s size shape. CFD results show that angle primarily affects shear stresses developed nozzle, predominantly impacts velocity pressure difference, shape stress, velocity, difference lesser extent compared size.

Language: Английский

Citations

0