Tuning Room-Temperature Injectability of Gelatin-Based Hydrogels via Introduction of Competitive Hydrogen Bonds

ACS Macro Letters, Journal Year: 2025, Volume and Issue: unknown, P. 313 - 319

Published: Feb. 24, 2025

As a natural biomaterial with superior comprehensive performance, gelatin has been widely explored in various biomedical and bioengineering applications. However, the ease of solidification solutions at room temperature causes great inconvenience specific application scenarios where injection is required. Here we addressed this problem by introduction competitive hydrogen bond (CHB)-containing substances to interfere original intergelatin bonds. Four representative CHB materials, metformin, l-arginine, polyarginine, polyurea, all showed remarkable efficiency tuning "sol-gel" phase transition concentration-dependent manner. Systematic rheological measurements indicated that addition materials significantly improved room-temperature injectability gelatin. Compared alone, CHB-containing bioinks printability shape fidelity 3D bioprinting.

Language: Английский

Application of 3D Printing Technology in Dentistry: A Review

Polymers, Journal Year: 2025, Volume and Issue: 17(7), P. 886 - 886

Published: March 26, 2025

Three-dimensional (3D) printing is a cutting-edge technology that widely used in biomedical fields to construct various commercial products or scaffolds for theoretical research. In this review, 3D technologies with different principles are briefly introduced, including selective laser melting (SLM), sintering (SLS), fused deposition modeling (FDM), stereolithography (SLA), and digital light processing (DLP). addition, the applications of dentistry, such as dental implantology, prosthodontics, orthodontics, maxillofacial surgery, tissue regeneration, were summarized. Furthermore, perspective challenges also addressed help readers obtain clear map development dentistry.

Language: Английский