Medical Oncology, Journal Year: 2025, Volume and Issue: 42(7)
Published: June 4, 2025
Language: Английский
Pharmaceutics, Journal Year: 2025, Volume and Issue: 17(3), P. 375 - 375
Published: March 15, 2025
Recent progress in material science has led to the development of new drug delivery systems that go beyond conventional approaches and offer greater accuracy convenience application therapeutic agents. This review discusses evolutionary role nanocarriers, hydrogels, bioresponsive polymers enhanced release, target accuracy, bioavailability. Oncology, chronic disease management, vaccine are some applications explored this paper show how these materials improve results, counteract multidrug resistance, allow for sustained localized treatments. The also translational barriers bringing advanced into clinical setting, which include issues biocompatibility, scalability, regulatory approval. Methods overcome challenges surface modifications reduce immunogenicity, scalable production methods such as microfluidics, harmonization systems. In addition, convergence artificial intelligence (AI) machine learning (ML) is opening frontiers personalized medicine. These technologies predictive modeling real-time adjustments optimize needs individual patients. use can be applied rare underserved diseases; thus, strategies gene therapy, orphan drugs development, global distribution may hopes millions
Language: Английский
Citations
4
Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: 14(4)
Published: Nov. 6, 2024
Cancer remains one of the most challenging health issues globally, demanding innovative therapeutic approaches for effective treatment. Nanoparticles, particularly those composed gold, silver, and iron oxide, have emerged as promising candidates changing cancer therapy. This comprehensive review demonstrates landscape nanoparticle-based oncological interventions, focusing on remarkable advancements potentials oxide nanoparticles. Gold nanoparticles garnered significant attention their exceptional biocompatibility, tunable surface chemistry, distinctive optical properties, rendering them ideal various diagnostic strategies. Silver nanoparticles, renowned antimicrobial exhibit potential in therapy through multiple mechanisms, including apoptosis induction, angiogenesis inhibition, drug delivery enhancement. With magnetic properties offer unique diagnosis targeted opportunities. critically examines recent synthesis, functionalization, biomedical applications these Moreover, challenges are discussed, toxicity concerns, immunogenicity, translational barriers, ongoing efforts to overcome hurdles highlighted. Finally, insights into future directions regulatory considerations, provided aiming accelerate translation technologies from bench bedside.
Language: Английский
Citations
17
Results in Engineering, Journal Year: 2025, Volume and Issue: unknown, P. 104238 - 104238
Published: Feb. 1, 2025
Language: Английский
Citations
1
Pharmaceutics, Journal Year: 2025, Volume and Issue: 17(3), P. 296 - 296
Published: Feb. 24, 2025
Melanoma, a highly aggressive form of skin cancer, poses major therapeutic challenge due to its metastatic potential, resistance conventional therapies, and the complexity tumor microenvironment (TME). Materials science nanotechnology advances have led using nanocarriers such as liposomes, dendrimers, polymeric nanoparticles, metallic nanoparticles transformative solutions for precision melanoma therapy. This review summarizes findings from Web Science, PubMed, EMBASE, Scopus, Google Scholar highlights role in overcoming treatment barriers. Nanoparticles facilitate passive active targeting through mechanisms enhanced permeability retention (EPR) effect functionalization with tumor-specific ligands, thereby improving accuracy drug delivery reducing systemic toxicity. Stimuli-responsive systems multi-stage further improve overcome challenges poor penetration resistance. Emerging platforms combine diagnostic imaging delivery, paving way personalized medicine. However, there are still issues scalability, biocompatibility, regulatory compliance. comprehensive potential integrating genetics proteomics, scalable, patient-specific therapies. These interdisciplinary innovations promise redefine provide safer, more effective, accessible treatments. Continued research is essential bridge gap between evidence-based scientific clinical applications.
Language: Английский
Citations
1
International Journal of Scientific Research in Science and Technology, Journal Year: 2025, Volume and Issue: 12(1), P. 161 - 173
Published: Jan. 26, 2025
Iron oxide nanoparticles (IONPs) have emerged as a transformative tool in oncology, offering unprecedented opportunities for early cancer diagnosis and effective treatment. These exhibit unique physicochemical properties, including superparamagnetism, biocompatibility, large surface area-to-volume ratio. properties make them particularly suitable applications such high-resolution imaging, targeted drug delivery, hyperthermia therapy. Additionally, their ability to be functionalized with various biomolecules enables precision targeting of cancerous tissues, further enhancing efficacy. This article delves into the cutting-edge advancements utilization IONPs, examines multifunctional roles addresses challenges clinical translation, outlines future directions research application this dynamic field.
Language: Английский
Citations
0
Crystal Growth & Design, Journal Year: 2025, Volume and Issue: unknown
Published: March 13, 2025
Language: Английский
Citations
0
International Journal of Smart and Nano Materials, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 34
Published: April 19, 2025
Language: Английский
Citations
0
Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 539, P. 216745 - 216745
Published: May 1, 2025
Language: Английский
Citations
0
Biomaterials Advances, Journal Year: 2025, Volume and Issue: 175, P. 214325 - 214325
Published: May 1, 2025
Language: Английский
Citations
0
Bioresource Technology, Journal Year: 2025, Volume and Issue: unknown, P. 132588 - 132588
Published: May 1, 2025
Language: Английский
Citations
0