Continuous magnetic-gradient hydrogel with augmented mechanical span and reverse-directional polysaccharides distribution for integrated repair of osteochondral defects DOI
Junwei Xu, Yi Cui, Xuemei Sun

et al.

Composites Part B Engineering, Journal Year: 2025, Volume and Issue: unknown, P. 112361 - 112361

Published: March 1, 2025

Language: Английский

Advancements in 3D Printing Technologies for Personalized Treatment of Osteonecrosis of the Femoral Head DOI Creative Commons
Tingting Chen,

Lincong Luo,

Jiaying Li

et al.

Materials Today Bio, Journal Year: 2025, Volume and Issue: 31, P. 101531 - 101531

Published: Feb. 5, 2025

Three-dimensional (3D) printing technology has shown significant promise in the medical field, particularly orthopedics, prosthetics, tissue engineering, and pharmaceutical preparations. This review focuses on innovative application of 3D addressing challenges osteonecrosis femoral head (ONFH). Unlike traditional hip replacement surgery, which is often suboptimal for younger patients, offers precise localization necrotic areas ability to create personalized implants. By integrating advanced biomaterials, this a promising strategy approach early hip-preserving treatments. Additionally, 3D-printed bone engineering scaffolds can mimic natural environment, promoting regeneration vascularization. In future, potential extends combining with artificial intelligence optimizing treatment plans, developing materials enhanced bioactivity compatibility, translating these innovations from laboratory clinical practice. demonstrates how uniquely addresses critical ONFH treatment, including insufficient vascularization, poor mechanical stability, limited long-term success conventional therapies. introducing gradient porous scaffolds, bioactive material coatings, AI-assisted design, work outlines novel strategies improve interventions. These advancements not only enhance efficacy but also pave way findings into applications.

Language: Английский

Citations

1

Continuous magnetic-gradient hydrogel with augmented mechanical span and reverse-directional polysaccharides distribution for integrated repair of osteochondral defects DOI
Junwei Xu, Yi Cui, Xuemei Sun

et al.

Composites Part B Engineering, Journal Year: 2025, Volume and Issue: unknown, P. 112361 - 112361

Published: March 1, 2025

Language: Английский

Citations

0