Biology, Journal Year: 2025, Volume and Issue: 14(6), P. 619 - 619

Published: May 27, 2025

Thermosensitive hydrogel, as a smart polymer material, showed great potential for application in the field of wound repair due to its unique external temperature responsiveness and excellent biocompatibility. Chitosan, natural macromolecular polysaccharide derived from deacetylation chitin, possessed not only strong interactions with biomolecules such DNA, proteins, lipids, but also biocompatibility degradability. Chitosan-based thermosensitive hydrogels, prepared by compounding chitosan surfactants, underwent sol–gel phase transitions at varying temperatures, which provided an ideal healing environment wounds. This comprehensive review was initiated elucidating transformation mechanism underlying hydrogels intricate process repair. In addition, this detailed overview prevalent types chitosan-based highlighting their characteristics applications different Finally, challenges development directions were discussed, aiming provide theoretical support practical guidance future healing.

Language: Английский