Applied Materials Today, Journal Year: 2024, Volume and Issue: 38, P. 102259 - 102259
Published: May 25, 2024
Language: Английский
Applied Materials Today, Journal Year: 2024, Volume and Issue: 38, P. 102259 - 102259
Published: May 25, 2024
Language: Английский
Journal of Controlled Release, Journal Year: 2024, Volume and Issue: 367, P. 661 - 675
Published: Feb. 8, 2024
Language: Английский
Citations
7Med, Journal Year: 2024, Volume and Issue: 5(4), P. 348 - 367.e7
Published: March 22, 2024
Language: Английский
Citations
7Frontiers in Bioengineering and Biotechnology, Journal Year: 2024, Volume and Issue: 12
Published: June 11, 2024
Gliomas are typical malignant brain tumours affecting a wide population worldwide. Operation, as the common treatment for gliomas, is always accompanied by postoperative drug chemotherapy, but cannot cure patients. The main challenges chemotherapeutic drugs have low blood-brain barrier passage rate and lot of serious adverse effects, meanwhile, they difficulty targeting glioma issues. Nowadays, emergence nanoparticles (NPs) delivery systems (NDDS) has provided new promising approach gliomas owing to their excellent biodegradability, high stability, good biocompatibility, toxicity, minimal effects. Herein, we reviewed types mechanisms NPs currently used in including passive active delivery. In particular, primarily focused on various hopeful (such liposome, chitosan, ferritin, graphene oxide, silica nanoparticle, nanogel, neutrophil, adeno-associated virus), discussed advantages, disadvantages, progress preclinical trials. Moreover, outlined clinical trials applied gliomas. According this review, provide an outlook prospects NDDS treating summarise some methods that can enhance specificity safety NPs, like surface modification conjugating ligands peptides. Although there still limitations these will offer potential curing
Language: Английский
Citations
7Journal of Controlled Release, Journal Year: 2024, Volume and Issue: 374, P. 639 - 652
Published: Sept. 4, 2024
Language: Английский
Citations
7Applied Materials Today, Journal Year: 2024, Volume and Issue: 38, P. 102259 - 102259
Published: May 25, 2024
Language: Английский
Citations
6