Towards Zero Carbon Buildings: Overcoming the Financial Constraints to the Adoption of Biogenic Building Materials DOI Open Access
Mahmoud Sodangi

The Open Construction and Building Technology Journal, Journal Year: 2024, Volume and Issue: 18(1)

Published: Dec. 27, 2024

Introduction The adoption of biogenic building materials is an important step towards decarbonizing the construction industry. However, a number constraints limit their wider in Objective To determine and analyse financial (FC) to materials; examine how they relate one another; provide strategy for overcoming promote utilization construction. Methods data study was obtained using methodical review related literature expert-based survey while results were analysed decision-making trial evaluation laboratory (DEMATEL) technique. Results findings indicate that most critical with strongest level cause on other FC are high initial costs (FC3), design & production cost (FC4), lack standardization certification (FC7), difficulty upscaling (FC1), limited access capital financing options (FC8). Conclusion This contributes advancing knowledge sustainable practices by determining understanding specific impede widespread within By addressing these constraints, promotes sector, contributing environmental conservation resource efficiency.

Language: Английский

Living plastics from plasticizer-assisted thermal molding of silk protein DOI Creative Commons
Yushu Wang, Junqi Wu,

Emily J. Hartzell

et al.

Nature Communications, Journal Year: 2025, Volume and Issue: 16(1)

Published: Jan. 2, 2025

The pursuit of materials, particularly plastics, with a minimal ecological footprint throughout their circular lifecycle, is crucial for advancing sustainable materials development. Living composed embedded yet active organisms can leverage endogenous biotic resources to achieve functional that align sustainability goals. However, current living material systems face challenges such as weak mechanical properties, limited environmental adaptability, and restricted cellular functionality. In this study, we propose an approach by incorporating into silk-based plastics through plasticizer-assisted thermal molding process. We investigate the mechanism structure formation in these correlating manufacturing performance resulting secondary structure. These provide protective matrix probiotics, ensuring survival harsh gastrointestinal tract enhancing intestinal delivery. Similarly, soil rhizobacteria encapsulated within exhibit long-term protease activity, accelerating plastic degradation upon exposure. This work demonstrates potential form where are processed, entrapped, retain metabolic functions, protected environments. goals, but usually adaptability Here, authors report thermoplastic process develop silk protein-based dense structures, functioning matrices microorganisms.

Language: Английский

Citations

4
Bacterial biomineralization of heavy metals and its influencing factors for metal bioremediation DOI

Souradip Mallick,

Trisnehi Pradhan,

Surajit Das

et al.

Journal of Environmental Management, Journal Year: 2025, Volume and Issue: 373, P. 123977 - 123977

Published: Jan. 1, 2025

Language: Английский

Citations

1
toward Practical Applications of Engineered Living Materials with Advanced Fabrication Techniques DOI

Chenjing Lu,

Yaying Huang,

Jian Cui

et al.

ACS Synthetic Biology, Journal Year: 2024, Volume and Issue: 13(8), P. 2295 - 2312

Published: July 13, 2024

Engineered Living Materials (ELMs) are materials composed of or incorporating living cells as essential functional units. These can be created using bottom-up approaches, where engineered spontaneously form well-defined aggregates. Alternatively, top-down methods employ advanced science techniques to integrate with various kinds materials, creating hybrids and intricately combined. ELMs blend synthetic biology science, allowing for dynamic responses environmental stimuli such stress, pH, humidity, temperature, light. exhibit unique "living" properties, including self-healing, self-replication, adaptability, making them highly suitable a wide range applications in medicine, conservation, manufacturing. Their inherent biocompatibility ability undergo genetic modifications allow customized functionalities prolonged sustainability. This review highlights the transformative impact over recent decades, particularly healthcare protection. We discuss current preparation methods, use endogenous exogenous scaffolds, assembly, 3D bioprinting, electrospinning. Emphasis is placed on ongoing research technological advancements necessary enhance safety, functionality, practical applicability real-world contexts.

Language: Английский

Citations

5
3D Bioprinting of Microbial-based Living Materials for Advanced Energy and Environmental Applications DOI Creative Commons

Xing‐Qun Pu,

Yuqi Wu, Junqiu Liu

et al.

Chem & Bio Engineering, Journal Year: 2024, Volume and Issue: 1(7), P. 568 - 592

Published: June 5, 2024

Microorganisms, serving as super biological factories, play a crucial role in the production of desired substances and remediation environments. The emergence 3D bioprinting provides powerful tool for engineering microorganisms polymers into living materials with delicate structures, paving way expanding functionalities realizing extraordinary performance. Here, current advancements microbial-based 3D-printed are comprehensively discussed from material perspectives, covering various techniques, types used, key parameters selection criteria polymer bioinks. Endeavors on applications printed fields energy environment then emphasized. Finally, remaining challenges future trends this burgeoning field highlighted. We hope our perspective will inspire some interesting ideas accelerate exploration within to reach superior solutions challenges.

Language: Английский

Citations

4
Engineering Bacteria for Environmental Release: Regulatory Challenges and Design Strategies DOI Creative Commons
Yonatan Chemla, Connor J. Sweeney,

Christopher A. Wozniak

et al.

Authorea (Authorea), Journal Year: 2024, Volume and Issue: unknown

Published: June 25, 2024

Promising many societal benefits, emergent products of biotechnology involve releasing genetically modified microbes (GMMs) into the environment.However, regulatory challenges limit their use.So far, GMMs have mainly been tested in agriculture and environmental cleanup, with few approved for commercial purposes.Current government regulations inadequately address modern genetic engineering potential gut therapeutics, skin products, self-repairing materials, ocean pollution treatment, anti-corrosion coatings, etc.This review first describes current U.S. engineered bacterial release.We analyze 57 global studies on soil-released laboratory microcosm experiments.We discuss behavior released bacteria offer guidelines to improve performance, control persistence, reduce risk.Advanced technologies that GMM function control, but lead increases scrutiny, are reviewed.Finally, we propose a new framework informed by recent data maximize benefits rapidly risks. v Box 1: Commercial releases bacteriaTo our knowledge, these examples only use.The example was not per se, it deployed field outside testing area perform its function.Supplementary Tables 2-3 describe published trials, most those commercially developed.Randomly-mutagenized included.Stopping Crown Gall disease trees antibiotic-producing bacteria.The pathogen Agrobacterium tumefaciens colonizes woody perennials, causing abnormal growth roots branches.It is killed agrocin, produced radiobacter K1026 29 , genes encoded plasmid, raising HGT concerns.Therefore, plasmid tra gene knocked out eliminate conjugative transfer 30 .In Australia 1988, became world's commercially-approved release.It 2000 United States 31 .Image crown gall taken Scot Nelson, creative commons license.Phenol remediated Pseudomonas putida.Phenol potent carcinogen due an 81-day fire at largest oil shale mine U.S.S.R. (now Estonia) 1988.Engineered P. putida containing recombinant phenol-degrading pathway spread remediate 32,33 .The were inoculated enclosures where reduced phenol levels 700-fold.Image showing diagram (6; location started), adapted from ref 34 .Bio-insecticides based Bacillus thuringiensis targeted pest control.B. produces proteins kill insects wild-type strains used bio-insecticide globally 35,36 .These disrupt different pests through variations endotoxins they produce (Cry proteins), strain may optimal combination toxins particular 36 .Mycogen Corporation developed M-Cap cloning Bt toxin B. fluorescens, facilitate use maize crops 37 before field.M-Cap 1990.Other similar developed, including prior release 22,[38][39][40] Stem borers, sensitive M-Cap, International Maize Wheat Improvement Center, license.Nitrogenous fertilizer delivery consortium.Nitrogenous consumes 2% energy major contributor runoff greenhouse gases 41 .Microbes do fixed N when conjunction synthetic unless engineered.In 1990s, Rhizobium meliloti got EPA approval legumes, never commercialized.In 2019, Pivot Bio commercialized Klebsiella variicola deliver nitrogen corn, later consortium adding Kosakonia sacchari.Their product millions acres replaced estimated 32,000 tons 2022 42 courtesy Bio.Engineered subtilis probiotic treating hangovers.Enzyme-based therapeutics often suffer inactivation stored or consumed.Activity could be improved if site needed body.Zbiotic over-thecounter liquid drink contains designed degrade gut-derived acetaldehyde builds up colon after consuming alcohol.The sale nearly 4 million bottles circulation as April 2024.Image Zbiotics.Oral cavity-reducing Streptococcus mutans lactic acid.Biofilms can cause dental cavities producing acid.An isolate S. found antibiotic mutacin 1140, increasing ability outcompete native colonize teeth 43 this strain, lactate dehydrogenase alcohol Zymomonas mobilis, using allelic exchange.The resulting stopped acid 44 .It one-time application cavity formation.While trying approve early 2000s oral therapeutic, FDA put constraints trial which completed.In 2023, Latern Bioworks brought market "cosmetic" avoid need permit.Image decay bacteria.By

Language: Английский

Citations

4
Unlocking the societal potential of engineered living materials DOI
Chelsea M. Heveran, Robin Gerlach, Christopher J. Hernandez

et al.

Matter, Journal Year: 2024, Volume and Issue: 7(9), P. 2846 - 2858

Published: Sept. 1, 2024

Language: Английский

Citations

4
Synthetic Biology‐Based Engineering Cells for Drug Delivery DOI Creative Commons

Wenzhe Yi,

Songnian Hu,

Xindi Qian

et al.

Exploration, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 16, 2025

ABSTRACT Although drug delivery technology has promoted the clinical translation of small molecule drugs, there is an urgent need for advanced systems to overcome complex physiological barriers and increasing development biological drugs. This review overviews emerging applications synthetic biology‐based engineered cells delivery. We first introduce biology strategies engineer discuss benefits in terms specificity, intelligence, controllability. Furthermore, we highlight cutting‐edge advancements at convergence nanotechnology Nanotechnology expands engineering design construction concepts biology, drives biotechnology‐driven nanomaterial synthesis. In future, may be developed more modular, standardized, intelligent, leading significant breakthroughs systems.

Language: Английский

Citations

0
Development of “environmentally friendly” super Escherichia coli strains that can completely biodegrade toluene DOI
Yu Wang, Cen Qian, Yongdong Deng

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 159877 - 159877

Published: Jan. 1, 2025

Language: Английский

Citations

0
Synthetic biology and parasite genomics: engineering parasite-resistant human microbiomes for sustainable disease prevention DOI Creative Commons
Esam S. Al‐Malki

Beni-Suef University Journal of Basic and Applied Sciences, Journal Year: 2025, Volume and Issue: 14(1)

Published: Feb. 18, 2025

Abstract Background Recent progress in parasite genomics has is enabled for greater understanding of genetic structure parasites, including the species Plasmodium, Leishmania, and Trypanosoma . Cutting-edge next-generation sequencing (NGS) techniques, such as high-throughput sequencing, discovery essential genes linked to metabolic pathways, drug resistance, life cycle adaptations. Advancements field have deep biological processes evolutionary adaptations parasites. Results Investigating genomes various strains enhanced our their adaptations, enhancing capacity predict epidemics develop therapies that effectively act against parasitic strains. Synthetic biology also proposed novel treatment approaches, gene bioengineered microbes, shows potential fighting or inhibiting illnesses. Revolutionary genome-editing methods, CRISPR-Cas9, accurate alterations, expediting sophisticated medicinal therapies, are specifically designed management eradication. Conclusion Microbiome engineering, an emerging area, provides a opportunities disease prevention by integrating techniques transplanting faecal microbiota genetically tailored bacteria restore microbial equilibrium decrease populations. Nevertheless, enduring stability modified microbiomes, possible environmental hazards, ethical concerns related editing emphasise necessity stringent safety measures monitoring regulatory authorities. Using these technologies responsibly ethically crucial guarantee continuous therapeutic advancement. Graphic abstract

Language: Английский

Citations

0
Harnessing chemistry for plant-like machines: from soft robotics to energy harvesting in the phytosphere DOI Creative Commons
Isabella Fiorello,

Yuanquan Liu,

Behnam Kamare

et al.

Chemical Communications, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Nature, especially plants, can inspire scientists and engineers in the development of bioinspired machines able to adapt interact with complex unstructured environments. Advances manufacturing techniques, such as 3D printing, have expanded range materials structures that be fabricated, enabling better adaptation specific applications closer mimicking natural systems. Furthermore, biohybrid systems-integrating plant-based or living materials-are getting attention for their ability introduce functionalities not possible purely synthetic materials. This joint feature article reviews highlights recent works two groups microfabrication plant-inspired robotics well plant-hybrid systems energy conversion soft environmental sensing, reforestation, autonomous drug-delivery plant tissue.

Language: Английский

Citations

0