Biomacromolecules,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 21, 2025
Conductive
polymers
have
been
shown
to
be
an
effective
scaffold
for
proteins
when
designing
bioelectrochemical
systems,
particularly
the
Photosystem
I
protein.
Utilization
of
synthetic
polymer
chemistry
has
allowed
a
great
deal
tunability
within
protein/polymer
interface
improve
electron
transfer
from
proteins,
ultimately
progressing
toward
direct
active
sites.
Seeking
address
this
issue,
new
heterogeneous
approach
is
presented
synthesize
I/polypyrrole
(PSI/PPy)
composites.
The
oxidative
potential
PSI's
P700
reaction
site
was
leveraged
polymerize
pyrrole
into
molecular
wire,
providing
more
efficient
means
Over
course
several
hours
photopolymerization
Py
in
PSI
film,
PPy
not
only
wired
but
began
incasing
protein
conductive
nanoparticles.
These
resulting
composite
nanoparticles
were
extensively
characterized
by
microscopy
and
electrochemical
techniques
showcase
their
synergistic
properties.
Journal of Colloid and Interface Science,
Journal Year:
2024,
Volume and Issue:
674, P. 392 - 404
Published: June 25, 2024
In
this
study,
we
present
a
nanocomposite
hydrogel
designed
for
skin
motion
sensing.
The
is
based
on
poly(acrylamide)
crosslinked
with
gold
nanoparticles
covalently
bound
to
the
polymer
matrix,
yielding
robust,
highly
elastic
and
conductive
material.
choice
of
amino
acid
derivative
-
N,N'-diacryloylcystine
salt
(BISS)
as
crosslinker
allows
introduction
nanoparticles,
due
presence
sulfide
groups
in
its
structure.
During
nanoparticle
modification
process,
covalent
bonds
between
sulfur
atoms
are
formed
disulfide
bond
cleaved.
result
self-assembly
multifunctional
Au-BISS
formed,
enhancing
material's
mechanical
properties
introducing
electrical
conductivity.
To
confer
anti-freezing
limit
water
evaporation,
binary
mixture
glycerol
was
used.
resultant
exhibits
high
elasticity,
strain
sensitivity
across
wide
range
various
types
deformation
(elongation,
bending,
compression)
exceptional
response
time
(120
ms)
recovery
(90
ms).
cold-resistance,
resilience,
conductivity
make
it
well-suited
real-time
monitoring
joint
movements
speech
recognition,
potential
applications
electronic
healthcare
devices.
Advanced Engineering Materials,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Jan. 25, 2024
Electrical
stimulation
has
shown
promise
in
clinical
studies
to
treat
nerve
injuries.
This
work
is
aimed
create
an
aligned
bioelectronic
construct
that
can
be
used
bridge
a
gap,
directly
interfacing
with
the
damaged
tissue
provide
growth
support.
The
conductive
three-dimensional
scaffolds
described
herein
are
composite
materials,
comprised
of
polypyrrole
(PPy)
nanoparticles
embedded
collagen
hydrogel.
constructs
seeded
dorsal
root
ganglion
derived
primary
rat
neurons
and
electrically
stimulated
vitro.
PPy
loaded
support
1.7-fold
increase
neurite
length
comparison
control
constructs.
Furthermore,
upon
electrical
PPy-collagen
construct,
1.8-fold
shown.
illustrates
potential
neural
engineering
lays
groundwork
for
development
novel
materials
applications.
Macromolecular Rapid Communications,
Journal Year:
2024,
Volume and Issue:
unknown
Published: June 8, 2024
Abstract
Soft
actuators
are
one
of
the
most
promising
technological
advancements
with
potential
solutions
to
diverse
fields’
day‐to‐day
challenges.
derived
from
hydrogel
materials
possess
unique
features
such
as
flexibility,
responsiveness
stimuli,
and
intricate
deformations,
making
them
ideal
for
soft
robotics,
artificial
muscles,
biomedical
applications.
This
review
provides
an
overview
material
composition
design
techniques
actuators,
exploring
3D
printing,
photopolymerization,
cross‐linking,
microfabrication
methods
improved
actuation.
It
examines
applications
in
biomedical,
bioinspired
systems,
microfluidics,
lab‐on‐a‐chip
devices,
environmental,
energy
systems.
Finally,
it
discusses
challenges,
opportunities,
advancements,
regulatory
aspects
related
actuators.
Advanced Materials,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Aug. 11, 2024
Abstract
The
low
electrical
conductivity
of
conductive
hydrogels
limits
their
applications
as
soft
conductors
in
bioelectronics.
This
originates
from
the
high
water
content
hydrogels,
which
impedes
facile
carrier
transport
between
fillers.
study
presents
a
highly
and
stretchable
hydrogel
nanocomposite
comprising
whiskered
gold
nanosheets.
A
dry
network
nanosheets
is
fabricated
then
incorporated
into
wet
matrices.
preserve
tight
interconnection
despite
content,
providing
high‐quality
percolation
even
under
stretched
states.
Regardless
type
matrix,
gold‐hydrogel
nanocomposites
exhibit
≈520
S
cm
−1
stretchability
≈300%
without
requiring
dehydration
process.
reaches
maximum
≈3304
when
density
controlled.
gold‐adhesive
nanocomposite,
can
achieve
conformal
adhesion
to
moving
organ
surfaces,
for
bioelectronics
demonstrations.
adhesive
electrode
outperforms
elastomer‐based
electrodes
vivo
epicardial
electrogram
recording,
pacing,
sciatic
nerve
stimulation.
Advanced Materials,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 28, 2024
Abstract
Fabricating
polymeric
composites
with
desirable
characteristics
for
electronic
applications
is
a
complex
and
costly
process.
Digital
light
processing
(DLP)
3D
printing
emerges
as
promising
technique
manufacturing
intricate
structures.
In
this
study,
samples
are
fabricated
conductivity
difference
exceeding
three
orders
of
magnitude
in
various
portions
part
by
employing
grayscale
DLP
(g‐DLP)
single‐vat
single‐cure
deliberate
resin
design.
This
realized
through
the
manipulation
intensity
during
curing
Specifically,
rational
design
added
lithium
ions
results
polymer
cured
under
maximum
UV‐light
exhibiting
higher
electrical
resistance.
Conversely,
sections
that
only
partially
retains
uncured
monomers,
serving
medium
facilitates
ion
mobility,
consequently
leading
to
conductivity.
The
versatility
g‐DLP
allows
precise
control
different
regions
characteristic
opens
up
possibilities
applications,
notably
low‐cost,
facile,
rapid
production
circuits
sensors.
utilization
makes
it
feasible
fabricate
materials
tailored
functionality,
providing
an
innovative
pathway
advance
accelerated
facile
creation
sophisticated
devices.
Advanced Materials,
Journal Year:
2024,
Volume and Issue:
37(2)
Published: Oct. 10, 2024
Abstract
The
healing
of
bone
defects
after
debridement
in
medication‐related
osteonecrosis
the
jaw
(MRONJ)
is
a
challenging
medical
condition
with
impaired
angiogenesis,
susceptible
infection,
and
pro‐inflammatory
responses.
Magnesium
(Mg)
nanocomposite
hydrogel
developed
to
specifically
tackle
multiple
factors
involved
MRONJ.
Mg‐oxide
nanoparticles
tune
gelation
kinetics
reaction
between
N‐hydroxysuccinimide‐functionalized
hyperbranched
poly
(ethylene
glycol)
proteins.
This
allows
an
enhanced
mechanical
property
instant
solidification
and,
more
importantly,
also
stable
environments
such
as
wet
hemorrhagic
conditions.
synthesized
guides
mandible
regeneration
MRONJ
rats
by
triggering
formation
type
H
vessels,
activating
Osterix+
osteoprogenitor
cells,
generating
anti‐inflammatory
microenvironments.
Additionally,
this
approach
demonstrates
its
ability
suppress
infection
inhibiting
specific
pathogens
while
strengthening
stress
tolerance
affected
alveolar
bone.
Furthermore,
osteogenic
properties
feasibility
implantation
are
validated
defect
iliac
crest
created
minipigs,
respectively.
Collectively,
study
offers
injectable
innovative
substitute
enhance
tackling
detrimental
pathologies.
Small Methods,
Journal Year:
2023,
Volume and Issue:
8(3)
Published: Nov. 27, 2023
Abstract
3D
printing
is
now
recognized
as
a
significant
tool
for
medical
research
and
clinical
practice,
leading
to
the
emergence
of
technology.
It
essential
improve
properties
3D‐printed
products
meet
demand
use.
The
core
generating
qualified
develop
advanced
materials
processes.
Taking
advantage
nanomaterials
with
tunable
distinct
physical,
chemical,
biological
properties,
integrating
nanotechnology
into
creates
new
opportunities
advancing
field.
Recently,
some
attempts
are
made
through
nanotechnology,
providing
insights
developing
With
high‐resolution
technology,
nano‐structures
can
be
directly
fabricated
applications.
Incorporating
material
system
products.
At
same
time,
used
expand
novel
technologies.
This
review
introduced
strategies
progresses
improving
discussed
challenges
in
translation.
