Digital electronics-free implantable drug delivery system for on-demand therapy DOI

Jooyeun Hu,

J. Zhang, Yufei Hou

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: unknown, P. 158763 - 158763

Published: Dec. 1, 2024

Language: Английский

Positive‐Positive Assembly Behavior in Liquid Metal Hydrogel Colloids DOI Open Access
Kong Weicheng, Ximin Yuan, Hongyu Chen

et al.

Advanced Functional Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 5, 2025

Abstract Negatively charged drug molecules can be efficiently assembled and controlled on the positively micro‐nanoparticle (MNP) surfaces by utilizing principle of electrostatic attraction. However, designing a system that protein factors are onto carriers through leveraging homophilic interactions remains formidable challenge. In solvents, interplay between repulsion van der Waals attraction among colloidal MNPs leads to phenomenon described in Derjaguin–Landau–Verwey–Overbeek (DLVO) theory. Is there designed enable assembly with MNPs? Here, novel photosensitive positive‐positive drugs is used as carrier, which named InGa 3 @polyvinylpyrrolidone (InGa @PVP). Under light excitation wavelength 365 nm, this exhibits attraction, enabling efficient entities. This discovery offers refined theoretical model for delivery applications, facilitating enhanced control optimization assembly.

Language: Английский

Citations

0

Progress in enzyme-powered micro/nanomotors in diagnostics and therapeutics DOI
Jinpeng Zhao,

Banghui Wang,

Mingzhe Yan

et al.

Bioactive Materials, Journal Year: 2025, Volume and Issue: 46, P. 555 - 568

Published: Jan. 13, 2025

Language: Английский

Citations

0

Improving glioblastoma treatment with imaging, radiotherapy, drug delivery, and therapeutic systems DOI Creative Commons
Katarzyna Mnich,

Stéphanie Lhomond,

Eimear Wallace

et al.

Device, Journal Year: 2025, Volume and Issue: unknown, P. 100685 - 100685

Published: Jan. 1, 2025

Language: Английский

Citations

0

Magnetic Continuum Robot for Intelligent Manipulation in Medical Applications DOI Creative Commons
Yuntao Ma, Xuanyu An,

Qijun Yang

et al.

Published: April 3, 2025

ABSTRACT Magnetic continuum robots (MCRs) have garnered substantial attention as a new class of flexible robotic systems capable navigating complex and confined spaces with remarkable dexterity. By combining continuous, deformable structures remotely applied magnetic fields, MCRs achieve contactless, remote manipulation, making them well‐suited for medical applications. This review introduces recent advances in MCR research, focusing on design principles, structural configurations, control strategies. Various designs structures, including those integrated permanent magnets, matter, ferromagnetic sphere, micro coil, are discussed. Furthermore, different actuation platforms introduced, the level automation is classified based Key intelligent manipulation capabilities MCRs, navigation, delivery, printing, grasping, imaging, sensing explored. Finally, future development priorities directions identified to provide insights advancing systems.

Language: Английский

Citations

0

An Exploration into the Current Application Status and Prospects of Nanorobots in Orthopedic Diseases Based on Their Medical Functions DOI Creative Commons
Qi Yang, Fei Yu

Nano Biomedicine and Engineering, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 1, 2024

Language: Английский

Citations

2

Innovative drug delivery strategies for targeting glioblastoma: overcoming the challenges of the tumor microenvironment DOI
Shubham Khot,

A. Krishnaveni,

Sankalp Gharat

et al.

Expert Opinion on Drug Delivery, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 15, 2024

Introduction - Glioblastoma multiforme(GBM) presents a challenging endeavor in therapeutic management because of its highly aggressive tumor microenvironment(TME). This complex TME, characterized by hypoxia, nutrient deprivation, immunosuppression, stromal barriers, increased interstitial fluid pressure and the presence blood-brain barrier(BBB), frequently compromises efficacy promising strategies. Consequently, deeper understanding TME development innovative methods to overcome associated challenges are essential for improving treatment outcomes GBM.

Language: Английский

Citations

2

Artificial intelligence advances drug delivery system and its clinical transition DOI
Hui Wang, Xiaoyan You, Guoping Zhao

et al.

Science Bulletin, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 1, 2024

Language: Английский

Citations

2

Revolutionizing Brain Tumor Care: Emerging Technologies and Strategies DOI Creative Commons
Trang Nguyen, Lloyd A. Greene, Hayk Mnatsakanyan

et al.

Biomedicines, Journal Year: 2024, Volume and Issue: 12(6), P. 1376 - 1376

Published: June 20, 2024

Glioblastoma multiforme (GBM) is one of the most aggressive forms brain tumor, characterized by a daunting prognosis with life expectancy hovering around 12–16 months. Despite century relentless research, only select few drugs have received approval for tumor treatment, largely due to formidable barrier posed blood–brain barrier. The current standard care involves multifaceted approach combining surgery, irradiation, and chemotherapy. However, recurrence often occurs within months despite these interventions. challenges drug delivery overcoming therapeutic resistance become focal points in treatment tumors are deemed essential recurrence. In recent years, promising wave advanced treatments has emerged, offering glimpse hope overcome limitations existing therapies. This review aims highlight cutting-edge technologies ongoing stages development, providing patients valuable insights guide their choices treatment.

Language: Английский

Citations

1

Recent Advances in the application of novel carriers for peptide delivery DOI Creative Commons
Shuang Wang, Qinlu Lin,

Ying Liang

et al.

Journal of Agriculture and Food Research, Journal Year: 2024, Volume and Issue: unknown, P. 101628 - 101628

Published: Dec. 1, 2024

Language: Английский

Citations

1

Stimuli-triggered pollen-inspired micro/nanorobots for advanced therapeutics DOI

Youjin Seol,

Keya Ganguly,

Hojin Kim

et al.

Nano Today, Journal Year: 2024, Volume and Issue: 57, P. 102337 - 102337

Published: June 3, 2024

Language: Английский

Citations

0