Construction of Frustrated Lewis Pairs for Efficient Artificial Enzyme

Advanced Functional Materials, Journal Year: 2025, Volume and Issue: unknown

Published: March 26, 2025

Abstract Optimizing the binding sites of substrates for small molecules activation plays a crucial role in enzyme‐like catalysts design. Herein, frustrated Lewis pairs (FLPs) are successfully constructed through boron (B) doping into CoO x (CoBO ) with abundant oxygen vacancies (O v ). The O optimizes valence active sites, creates coordinatively unsaturated state, and elongates distance pairs. electron‐deficient acid (LA) (Co) facilitate adsorption dissociation 2 , electron‐rich base (LB) (O) draw positively charged TMB closer to Co shorten reaction distance, which synergistically improve oxidase (OXD)‐like activity. Besides, increase electron density induced by FLPs promotes electrons transfer, intermediates stabilization, decreases energy barrier rate‐determining step . Significantly, proof‐of‐concept application colorimetric biosensing platform, as‐developed CoBO demonstrate highly sensitive selective detection capacity dopamine (DA) targets. This work verifies possibility activating catalysis.

Language: Английский

---

Dual-Mode Sensor Based on a Single-Atom Cobalt Catalyst for Simultaneous Electrochemical and Colorimetric Detection of Bioactive Small Molecules

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: April 9, 2025

The design of single-atom catalysts with dual functions has emerged as a promising strategy for developing high-performance sensing platforms. Herein, we reported facile host-guest synthesizing an atomically dispersed Co catalyst (Co-N-C), where atoms were uniformly anchored on the N-doped carbon matrix derived from zeolitic imidazolate framework-8. as-prepared Co-N-C exhibits both excellent electrochemical and peroxidase-like colorimetric activities toward detection three important bioactive small molecules, ascorbic acid (AA), dopamine (DA), uric (UA). sensor demonstrated ultrahigh sensitivity limits 4.83, 1.36, 0.371 μM AA, DA, UA, respectively, along outstanding selectivity against common interferents stable performance. Meanwhile, method also showed analytical performance 2.24 3.09 2.97 results indicate that electronic modulation through precise nitrogen coordination enhances affinity Co-Nx target reactants, thereby promoting adsorption electron transfer throughout reaction. This improves catalytic efficiency selectivity, establishing dual-catalytic functionality material biosensing applications.

Language: Английский

---

Role of advanced cleaning and sanitation techniques in biofilm prevention on dairy equipment

Comprehensive Reviews in Food Science and Food Safety, Journal Year: 2025, Volume and Issue: 24(3)

Published: April 22, 2025

Abstract Biofilm formation on dairy equipment is a persistent challenge in the industry, contributing to product contamination, inefficiency, and economic losses. Traditional methods such as manual cleaning basic chemical sanitation are discussed foundational approaches, followed by an in‐depth investigation of cutting‐edge technologies, including clean‐in‐place systems, high‐pressure cleaning, foam ultrasonic electrochemical dry ice blasting, robotics, nanotechnology‐based agents, enzymatic cleaners, oxidizing agents. Enhanced techniques, steam, pulsed light, acidic alkaline electrolyzed water, hydrogen peroxide vapor, microbubble technology, biodegradable biocides, highlighted for their potential achieve superior while promoting sustainability. The effectiveness, feasibility, limitations these evaluated, emphasizing role maintaining hygiene reducing biofilm‐associated risks. Additionally, challenges, compatibility, cost, regulatory compliance, addressed, along with insights into future directions innovations, automation, smart green solutions. This review provides comprehensive resource researchers, industry professionals, policymakers aiming tackle biofilm production systems enhance food safety, operational efficiency,

Language: Английский

---

Two birds with one stone: colorimetric and photothermal dual-mode biosensor based on CoOOH nanorings for detecting β-galactosidase activity and Escherichia coli

Chemical Communications, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

A multi-colorimetric and portable photothermal dual-mode biosensor with cross-references self-calibration was established for the analysis of β-galactosidase (β-Gal) Escherichia coli ( E. ).

Language: Английский

---

Accelerated reconstruction of ZIF-67 with significantly enhanced glucose detection sensitivity

Nano Research, Journal Year: 2024, Volume and Issue: 17(6), P. 4737 - 4743

Published: Jan. 25, 2024

Language: Английский

---