Hybrid 3D microfluidic bioprinting for the engineering of cancer models and tissue substitutes DOI Creative Commons
Salvatore D’Alessandro, Sajad Mohammadi, Lucia Iafrate

et al.

Virtual and Physical Prototyping, Journal Year: 2024, Volume and Issue: 19(1)

Published: Nov. 4, 2024

3D bioprinting is at the forefront of tissue engineering to fabricate complex constructs resembling functional tissues. However, inability produce heterogeneous tissues and lack spatio-temporal control over release bioactive factors are greatly limiting clinical translation. Herein, combination with high-throughput dispensing using a custom microfluidic system nanoclay-based inks presented. This approach was found enhance printability, retention, controlled factors. Advanced models were developed resemble cancer skeletal tissue, while studying effect anti-cancer (Doxorubicin) pro-osteogenic growth (bone morphogenetic protein-2, BMP-2), respectively. The new nanoclay ink allowed sustained release, making it suitable for long-term applications. These findings suggest that by combining delivery platform can be assembled, offering significant advancements in regenerative medicine.

Language: Английский

Unveiling the potential of biomaterials and their synergistic fusion in tissue engineering DOI Creative Commons
Eva Sanchez Armengol, Nathalie Hock,

Sila Saribal

et al.

European Journal of Pharmaceutical Sciences, Journal Year: 2024, Volume and Issue: 196, P. 106761 - 106761

Published: April 3, 2024

Inspired by nature, tissue engineering aims to employ intricate mechanisms for advanced clinical interventions, unlocking inherent biological potential and propelling medical breakthroughs. Therefore, medical, pharmaceutical fields are growing interest in organ replacement, repair, regeneration this technology. Three primary currently used engineering: transplantation of cells (I), injection growth factors (II) cellular seeding scaffolds (III). However, develop presenting highest potential, reinforcement with polymeric materials is interest. For instance, natural synthetic polymers can be used. Regardless, chitosan keratin two biopolymers great biocompatibility, biodegradability non-antigenic properties purposes offering restoration revitalization. combination has been studied results exhibit highly porous providing optimal environment cultivation. This review give an historical as well current overview engineering, involved the field.

Language: Английский

Citations

8

High-performance magnetic metal microrobot prepared by a two-photon polymerization and sintering method DOI
Rui Li,

Modong Jiang,

Bingrui Liu

et al.

Lab on a Chip, Journal Year: 2024, Volume and Issue: 24(4), P. 832 - 842

Published: Jan. 1, 2024

A high-performance pure-nickel magnetically-actuated microrobot (Ni-MAR) is printed by a ‘femtosecond laser polymerization + sintering’ method with great potential applications in controlled locomotion fast-flowing blood and massive drugs delivery.

Language: Английский

Citations

7

Biocompatible piezoelectric lattice materials with ultrasound-regulated multimodal responses DOI
Annan Chen, Jin Su, Muran Zhou

et al.

Materials Science and Engineering R Reports, Journal Year: 2024, Volume and Issue: 162, P. 100876 - 100876

Published: Nov. 16, 2024

Language: Английский

Citations

7

Application of 3D, 4D, 5D, and 6D bioprinting in cancer research: what does the future look like? DOI
Danial Khorsandi,

Dorsa Rezayat,

Serap Sezen

et al.

Journal of Materials Chemistry B, Journal Year: 2024, Volume and Issue: 12(19), P. 4584 - 4612

Published: Jan. 1, 2024

Recent advancements pertaining to the application of 3D, 4D, 5D, and 6D bioprinting in cancer research are discussed, focusing on important challenges future perspectives.

Language: Английский

Citations

5

Hybrid 3D microfluidic bioprinting for the engineering of cancer models and tissue substitutes DOI Creative Commons
Salvatore D’Alessandro, Sajad Mohammadi, Lucia Iafrate

et al.

Virtual and Physical Prototyping, Journal Year: 2024, Volume and Issue: 19(1)

Published: Nov. 4, 2024

3D bioprinting is at the forefront of tissue engineering to fabricate complex constructs resembling functional tissues. However, inability produce heterogeneous tissues and lack spatio-temporal control over release bioactive factors are greatly limiting clinical translation. Herein, combination with high-throughput dispensing using a custom microfluidic system nanoclay-based inks presented. This approach was found enhance printability, retention, controlled factors. Advanced models were developed resemble cancer skeletal tissue, while studying effect anti-cancer (Doxorubicin) pro-osteogenic growth (bone morphogenetic protein-2, BMP-2), respectively. The new nanoclay ink allowed sustained release, making it suitable for long-term applications. These findings suggest that by combining delivery platform can be assembled, offering significant advancements in regenerative medicine.

Language: Английский

Citations

5