Site‐Selective Biofunctionalization of 3D Microstructures Via Direct Ink Writing DOI Creative Commons
George Mathew, Enrico Domenico Lemma,

Dalila Fontana

et al.

Small, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 18, 2024

Abstract Two‐photon lithography has revolutionized multi‐photon 3D laser printing, enabling precise fabrication of micro‐ and nanoscale structures. Despite many advancements, challenges still persist, particularly in biofunctionalization microstructures. This study introduces a novel approach combining two‐photon with scanning probe for post‐functionalization microstructures overcoming limitations achieving spatially controlled biomolecule distribution. The method utilizes diverse range inks, including phospholipids, two different proteins, introducing high spatial resolution distinct functionalization on separate areas the same microstructure. surfaces are treated using bovine serum albumin and/or 3‐(Glycidyloxypropyl)trimethoxysilane (GPTMS) to enhance ink retention. further demonstrates strategies create binding sites cells by integrating biomolecules, showcasing potential customized cell microenvironments. Specific adhesion onto functionalized microscaffolds is demonstrated, which paves way applications tissue engineering, biointerfacing electronic devices biomimetic modeling.

Language: Английский

Fraxicon for Optical Applications with Aperture ∼1 mm: Characterisation Study DOI Creative Commons
Haoran Mu, Daniel Smith, Soon Hock Ng

et al.

Nanomaterials, Journal Year: 2024, Volume and Issue: 14(3), P. 287 - 287

Published: Jan. 30, 2024

Emerging applications of optical technologies are driving the development miniaturised light sources, which in turn require fabrication matching micro-optical elements with sub-1 mm cross-sections and high quality. This is particularly challenging for spatially constrained biomedical where reduced dimensionality required, such as endoscopy, optogenetics, or implants. Planarisation a lens by Fresnel approach was adapted conical (axicon) made direct femtosecond 780 nm/100 fs laser writing SZ2080™ polymer photo-initiator. Optical characterisation positive negative fraxicons presented. Numerical modelling fraxicon performance under illumination incoherent extended sources compared ideal case plane-wave illumination. Considering potential rapid replication soft polymers resists, this holds great promise most demanding technological applications.

Language: Английский

Citations

0
Bi-Material 3D Printed Soft Microrobots: Proof-of-Concept and Demonstration DOI

Mehdi Salah,

Yannis Bordes,

Cédric Clévy

et al.

Published: July 1, 2024

Language: Английский

Citations

0
Interferometric microscale measurement of refractive index at VIS and IR wavelengths DOI Creative Commons
Meguya Ryu,

Simonas Varapnickas,

Darius Gailevičius

et al.

SciPost Physics Core, Journal Year: 2024, Volume and Issue: 7(3)

Published: Aug. 30, 2024

Determination of refractive index micro-disks a calcinated ( 1100^\circ 1100∘ C in air) photo-resist SZ2080 ^\mathrm{TM} display="inline">TM was carried out using transmission and reflection spectroscopy. Interference fringes at specific wavenumbers/wavelengths were selected for determination the optical thickness, hence, when thickness measured by scanning electron microscopy (SEM). Refractive disks \sim 6± 1~\mu display="inline">∼6±1μ m determined visible IR (2.5-13~ \mu display="inline">μ m) spectral ranges where 2.2± 0.2 display="inline">2.2±0.2 wavelengths. Peculiarities characterisation micro-optical structures are discussed view possible uncertainties definition geometric parameters, shape mass density redistribution.

Language: Английский

Citations

0
Optical fiber integrated functional elements fabricated by two-photon polymerization DOI
Stella Aslanoglou, Barbara Spagnolo, Ferruccio Pisanello

et al.

Published: July 14, 2024

Language: Английский

Citations

0
Site‐Selective Biofunctionalization of 3D Microstructures Via Direct Ink Writing DOI Creative Commons
George Mathew, Enrico Domenico Lemma,

Dalila Fontana

et al.

Small, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 18, 2024

Abstract Two‐photon lithography has revolutionized multi‐photon 3D laser printing, enabling precise fabrication of micro‐ and nanoscale structures. Despite many advancements, challenges still persist, particularly in biofunctionalization microstructures. This study introduces a novel approach combining two‐photon with scanning probe for post‐functionalization microstructures overcoming limitations achieving spatially controlled biomolecule distribution. The method utilizes diverse range inks, including phospholipids, two different proteins, introducing high spatial resolution distinct functionalization on separate areas the same microstructure. surfaces are treated using bovine serum albumin and/or 3‐(Glycidyloxypropyl)trimethoxysilane (GPTMS) to enhance ink retention. further demonstrates strategies create binding sites cells by integrating biomolecules, showcasing potential customized cell microenvironments. Specific adhesion onto functionalized microscaffolds is demonstrated, which paves way applications tissue engineering, biointerfacing electronic devices biomimetic modeling.

Language: Английский

Citations

0