Micro‐ and nanorobots from magnetic particles: Fabrication, control, and applications DOI Creative Commons

Xiaoyu Wang,

Tao Yang, Quan Li

et al.

Deleted Journal, Journal Year: 2024, Volume and Issue: 2(4)

Published: Nov. 1, 2024

Abstract Magnetic microparticles (MPs) and nanoparticles (NPs) have long been used as ideal miniaturized delivery detection platforms. Their use micro‐ nanorobots (MNRs) is also emerging in the recent years with help of more dedicated external magnetic field manipulations. In this review, we summarize research progress on nanoparticle (MNP)‐based MNRs. First, fabrication from either template‐assisted NP doping methods or directly synthesized MPs summarized. The driving torque sources for both types MNRs are analyzed, their propulsion control under low Reynolds number flows discussed by evaluating symmetry breaking mechanisms interparticle interactions. Subsequently, these scientific models, bioimaging agents, active delivery, treatment platforms (drug cell sterilization), biomedical diagnostics has reviewed. Finally, perspective MNPs‐based was outlined, including challenges future directions.

Language: Английский

AlgaeSperm: Microalgae‐Based Soft Magnetic Microrobots for Targeted Tumor Treatment DOI Open Access
Nuoer Celi, De Gong, Jun Cai

et al.

Small, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 13, 2025

Abstract Magnetic microrobots are significant platforms for targeted drug delivery, among which sperm‐inspired types have attracted much attention due to their flexible undulation. However, mass production of sperm‐like soft magnetic with high‐speed propulsion is still challenging the need more reasonable structure design and facile fabrication. Herein, a novel strategy proposed large‐scale preparation microalgae‐based fully head‐to‐tail structure, called AlgaeSperm robust chemo‐photothermal performance. This approach deposited Pd@Au nanoparticles (NPs) inside chlorella cells, further coated Fe 3 O 4 NPs polydopamine layers form heads. Then, flagella grafted via assembly @PVP construct final AlgaeSperm. Under precessing fields, AlgaeSperms can achieve forward velocity up 2.3 body length/s, highest best knowledge. Besides, maneuverability in swarm also verified. In vitro anti‐cancer experiments conducted after loading doxorubicin (DOX) confirm excellent work offers paradigm constructing great potential tumor treatment.

Language: Английский

Citations

1

Multiorifice acoustic microrobot for boundary-free multimodal 3D swimming DOI Creative Commons
Nima Mahkam, Musab Cagri Ugurlu, Sandeep Kumar Kalva

et al.

Proceedings of the National Academy of Sciences, Journal Year: 2025, Volume and Issue: 122(4)

Published: Jan. 22, 2025

The emerging new generation of small-scaled acoustic microrobots is poised to expedite the adoption microrobotics in biomedical research. Recent designs these have enabled intricate bioinspired motions, paving way for their real-world applications. We present a multiorifice design air-filled spherical that convert wave energy efficient propulsion through resonant encapsulated microbubble. These can swim boundary-free three-dimensional (3D) space while switching between various frequency-dependent locomotion modes. explore dynamics with diameters ranging from 10 μm 100 μm, focusing on 3D swimming and multimodal response stimuli below 1 MHz. Further, we elucidate microrobots, featuring single cavity, which contributes complex streaming facilitates swift, unrestricted movements. Finally, demonstrate incorporating additional nickel gold layers significantly enhances steering visibility optoacoustic ultrasound imaging, enabling development next healthcare

Language: Английский

Citations

1

Metareview: a survey of active matter reviews DOI Creative Commons
Michael te Vrugt, Raphael Wittkowski

The European Physical Journal E, Journal Year: 2025, Volume and Issue: 48(2)

Published: Feb. 1, 2025

In the past years, amount of research on active matter has grown extremely rapidly, a fact that is reflected in particular by existence more than 1000 reviews this topic. Moreover, field become very diverse, ranging from theoretical studies statistical mechanics particles to applied work medical applications microrobots and biological systems artificial swimmers. This makes it difficult get an overview over as whole. Here, we provide such form metareview article surveys existing review articles books matter. Thereby, provides useful starting point for finding literature about specific

Language: Английский

Citations

1

Anticoagulation colloidal microrobots based on heparin-mimicking polymers DOI
Huanhuan Wang, Huaguang Wang, Xiaoli Liu

et al.

Journal of Colloid and Interface Science, Journal Year: 2025, Volume and Issue: unknown, P. 137345 - 137345

Published: March 1, 2025

Language: Английский

Citations

1

Light-Driven Microrobots for Targeted Drug Delivery DOI
Qilong Cheng,

Xingqi Lu,

Yunhao Tai

et al.

ACS Biomaterials Science & Engineering, Journal Year: 2024, Volume and Issue: 10(9), P. 5562 - 5594

Published: Aug. 15, 2024

As a new micromanipulation tool with the advantages of small size, flexible movement and easy manipulation, light-driven microrobots have wide range prospects in biomedical fields such as drug targeting cell manipulation. Recently, been controlled various ways, light field has become research hotspot by its noncontact precise localization, fast response, biocompatibility. It utilizes force or deformation generated to precisely control microrobot, combines release technology realize targeted application. Therefore, this paper provides an overview provide ideas for manipulation microrobots. Here, briefly categorizes driving mechanisms materials microrobots, which mainly include photothermal, photochemical, biological. Then, typical designs different strategies multiple physical are summarized. Finally, applications bioimaging presented well future demonstrated.

Language: Английский

Citations

5

Microrotors with Tunable Trajectory Curvatures Driven by Chemical and Photochemical Dual Engines DOI

Ruitong Zhu,

Donghao Cui,

Dezhou Cao

et al.

ACS Materials Letters, Journal Year: 2025, Volume and Issue: unknown, P. 668 - 674

Published: Jan. 23, 2025

A major challenge in developing smart micromachines that can mimic natural microorganisms is their ability to adapt changing environments. This study presents a matchstick-shaped microrotor consisting of TiO2 head and SiO2 tail, with one side coated by PtO. The provides photochemical propulsion under UV light, while the PtO coating chemical H2O2. rotates because its asymmetric structure uneven forces. Notably, stronger rotor orbits tighter circles as engine counteracts engine, two engines located on opposite sides center mass. Additionally, microrotors shorter tails moved smaller were more sensitive changes light intensity.

Language: Английский

Citations

0

Anticoagulation Colloidal Microrobots Based on Heparin-Mimicking Polymers DOI
Huanhuan Wang, Huaguang Wang, Xiaoli Liu

et al.

Published: Jan. 1, 2025

Language: Английский

Citations

0

Micro/Nanorobots for Advanced Light‐Based Biosensing and Imaging DOI Creative Commons

Aparna Neettiyath,

Martin Pumera

Advanced Functional Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 6, 2024

Abstract Sensing and imaging of biomolecules are crucial to disease diagnosis, prognosis, therapy where optical techniques have essential utility. Untethered remotely controlled micro/nanorobots shown promising sensing capabilities, especially in complex biological environments. In this review, how used for biosensing while highlighting the significant developments field is discussed. Starting done by exploring colorimetric methods enabled micro/nanorobots. Significant advancements surface‐enhanced Raman spectroscopy‐integrated reviewed. Further, state‐of‐the‐art bio‐imaging applications at vitro intracellular level highlighted. Novel vivo assisted micro/nanorobot sensors examined. Furthermore, innovations assessed motion augmentation as a detection mechanism, with point‐of‐care molecular diagnostics. Finally, challenges associated micro/nanorobots‐assisted advanced discussing insights about potential research directions rapidly progressing summarized.

Language: Английский

Citations

3

Magnetic Alginate Microrobots with Dual-Motion Patterns through Centrifugally Driven Flow Control DOI Creative Commons
Zihan Wang, Wenjian Li, Chuang Li

et al.

Materials & Design, Journal Year: 2024, Volume and Issue: unknown, P. 113337 - 113337

Published: Sept. 1, 2024

Language: Английский

Citations

1

Self‐Propelled Morphing Matter for Small‐Scale Swimming Soft Robots DOI Creative Commons
Chuqi Huang,

Natalie P. Pinchin,

Chia‐Heng Lin

et al.

Advanced Functional Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 1, 2024

Abstract Aquatic insects have developed versatile locomotion mechanisms that served as a source of inspiration for decades in the development small‐scale swimming robots. However, despite recent advances field, efficient, untethered, and integrated powering, actuation, control robots remains challenge due to out‐of‐equilibrium dissipative nature driving physical chemical phenomena. Here, we designed small‐scale, bioinspired aquatic locomotors with programmable deterministic trajectories integrate self‐propelled motors photoresponsive shape‐morphing structures. A Marangoni motor system is integrating structural protein networks self‐regulate release fuel photochemical liquid crystal network (LCN) actuators change their shape deform out surface water. While diffusion from regulates propulsion, deformation LCNs provides over directionality motion at air‐water interface. This approach gives access five different but interchangeable modes within single robot via morphing soft structure. The proposed design, which mimics gliding posture semiaquatic such water treaders, offers solutions autonomous untethered orthogonal power control.

Language: Английский

Citations

1