Laser-induced
graphene
(LIG)
has
emerged
as
a
promising
solvent-free
strategy
for
producing
highly
porous,
3D
structures,
particularly
electrochemical
applications.
However,
the
unique
character
of
LIG
and
hydrogel
membrane
(HM)
coated
requires
accounting
specific
conditions
its
charge
transfer
process.
This
study
investigates
electron
kinetics
electroactive
surface
area
electrodes,
finding
efficient
[Fe(CN)6]3-/4-
redox
process,
with
high
rate
constant
4.12
x
10-3
cm/s
an
28
times
higher
than
geometric
area.
The
impact
polysaccharide
HM
coatings
(cationic
chitosan,
neutral
agarose
anionic
sodium
alginate)
on
LIG's
behavior
is
elucidated,
considering
factors
like
Ohmic
drop
across
porous
Coulombic
interactions/permeability
affecting
diffusion
coefficients,
estimated
from
amperometry.
Experimental
findings
are
supported
by
ab-initio
calculations
showing
electrostatic
potential
map’s
negative
distribution
upon
chitosan
chain
protonation,
having
effect
in
over
two-fold
current
increase
switching
pH
7.48
to
1.73.
feature
absent
other
studied
HMs.
It
was
also
revealed
that
chitosan's
band
gap
reduced
3.07
eV
acetylation,
due
introduction
new
LUMO
state.
summarizes
operating
enhanced
presence,
impacting
process
presenting
challenges
prospective
LIG/HM
systems’
ACS Applied Bio Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 11, 2025
Bletilla
striata
polysaccharide
(BSP)
is
effective
at
healing
wounds
and
has
important
application
value
in
the
research
development
of
biomedical
materials.
In
this
study,
BSP,
chitosan,
sodium
β-glycerophosphate
were
used
to
generate
a
complex
hydrogel
with
very
small
pore
size
10-30
μm
without
use
cross-linking
agents.
By
improving
density,
mechanical
property
defects
caused
by
excessive
BSP
dissolution
overcome
affecting
its
physiological
activity.
Moreover,
molecule
Danshen
(SDSS)
was
loaded
into
three-dimensional
network
form
drug
carrier
system.
SDSS
could
be
released
long
term,
total
amount
after
53
h
96.26
±
2.57%.
The
had
good
water
absorption
(169.47
4.54%)
bonding
properties.
vitro
studies
confirmed
that
it
antibacterial
performance
biocompatibility
ability
promote
cell
proliferation
(>200%)
migration.
Molecular
experiments
promotes
collagen
expression.
vivo
using
mouse
wound
model
an
excellent
healing,
particularly
during
first
7
days
wound.
rate
group
higher
than
blank
27.61%
(p
<
0.05),
effect
tissue
staining.
ACS Nano,
Journal Year:
2024,
Volume and Issue:
18(37), P. 25841 - 25851
Published: Sept. 6, 2024
Competitive
binding
of
distinct
molecules
in
the
hydrogel
interior
can
facilitate
dynamic
exchange
between
and
surrounding
environment.
The
ability
to
control
rates
sequestration
release
these
would
enhance
hydrogel's
functionality
enable
targeting
a
specific
task.
Here,
we
report
design
colloidal
with
two
pore
dimensions
achieve
staged,
diffusion-controlled
scavenging
dynamics
undergoing
competitive
binding.
staged
strategy
was
shown
for
CpG
oligodeoxynucleotide
(ODN)
human
epidermal
growth
factor
(hEGF),
exhibiting
different
affinities
quaternary
ammonium
groups
hydrogel.
Fast
ODN
from
ambient
environment
occurred
via
diffusion
through
submicrometer-size
pores,
while
delayed
hEGF
governed
by
its
nanometer-size
pores.
results
experiments
were
agreement
simulation
results.
significance
ODN-hEGF
highlighted
dual
anti-inflammation
tissue
proliferation
performance.
Advanced Functional Materials,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 10, 2024
Abstract
Osteoarthritis
is
a
prevalent
chronic
health
condition
that
mostly
associated
with
the
degeneration
of
joint
cartilage
due
to
aging
or
abnormal
mechanical
stress
in
joint.
Intraarticularly
injected
nanoparticle‐based
lubricants
decrease
friction
between
damaged
surfaces,
thus
preventing
their
further
degradation;
however,
effectiveness
currently
used
limited
by
short
retention
time
space.
To
address
this
challenge,
cationically
modified
biosourced
phytoglycogen
nanolubricants
are
utilized,
which
electrostatically
bind
components.
The
conjugation
nanoparticles
red‐emissive
fluorescent
carbon
dots
enables
vivo
studies
hytoglycogen
nanoconjugates
exhibit
high
colloidal
stability
physiological
conditions,
provide
coefficient
10
−3
–10
−2
sliding
surfaces
under
physiologically
relevant
pressures,
strongly
major
surface
components,
and
show
significantly
prolonged
vivo,
fourfold
increase
half‐life
comparison
conventionally
hyaluronic
acid
injectant.
These
properties
make
these
functionalized
highly
promising
candidate
for
lubrication.
Laser-induced
graphene
(LIG)
has
emerged
as
a
promising
solvent-free
strategy
for
producing
highly
porous,
3D
structures,
particularly
electrochemical
applications.
However,
the
unique
character
of
LIG
and
hydrogel
membrane
(HM)
coated
requires
accounting
specific
conditions
its
charge
transfer
process.
This
study
investigates
electron
kinetics
electroactive
surface
area
electrodes,
finding
efficient
[Fe(CN)6]3-/4-
redox
process,
with
high
rate
constant
4.12
x
10-3
cm/s
an
28
times
higher
than
geometric
area.
The
impact
polysaccharide
HM
coatings
(cationic
chitosan,
neutral
agarose
anionic
sodium
alginate)
on
LIG's
behavior
is
elucidated,
considering
factors
like
Ohmic
drop
across
porous
Coulombic
interactions/permeability
affecting
diffusion
coefficients,
estimated
from
amperometry.
Experimental
findings
are
supported
by
ab-initio
calculations
showing
electrostatic
potential
map’s
negative
distribution
upon
chitosan
chain
protonation,
having
effect
in
over
two-fold
current
increase
switching
pH
7.48
to
1.73.
feature
absent
other
studied
HMs.
It
was
also
revealed
that
chitosan's
band
gap
reduced
3.07
eV
acetylation,
due
introduction
new
LUMO
state.
summarizes
operating
enhanced
presence,
impacting
process
presenting
challenges
prospective
LIG/HM
systems’
