Sensors & Diagnostics, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 13, 2024
This review provides a summary and an outlook on the challenges prospects associated with commercialization of GFET technology in biosensing field.
Language: Английский
Advanced Materials, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 3, 2025
Abstract This review underscores the transformative potential of photonic nanomaterials in wearable health technologies, driven by increasing demands for personalized monitoring. Their unique optical and physical properties enable rapid, precise, sensitive real‐time monitoring, outperforming conventional electrical‐based sensors. Integrated into ultra‐thin, flexible, stretchable formats, these materials enhance compatibility with human body, enabling prolonged wear, improved efficiency, reduced power consumption. A comprehensive exploration is provided integration devices, addressing material selection, light‐matter interaction principles, device assembly strategies. The highlights critical elements such as form factors, sensing modalities, data communication, representative examples skin patches contact lenses. These devices precise monitoring management biomarkers diseases or biological responses. Furthermore, advancements approaches have paved way continuum care systems combining multifunctional sensors therapeutic drug delivery mechanisms. To overcome existing barriers, this outlines strategies design, engineering, system integration, machine learning to inspire innovation accelerate adoption next‐generation health, showcasing their versatility digital applications.
Language: Английский
Citations
2
Published: Jan. 19, 2025
Language: Английский
Citations
0
ACS Nano, Journal Year: 2025, Volume and Issue: unknown
Published: April 2, 2025
For highly efficient and precise drug release, transdermal delivery systems (TDDS) have recently evolved through the combination of intelligent material-based structures with various active components. These strategies are an effort to overcome significant difficulties in delivering large molecule drugs nanomaterials due physical barrier skin, especially stratum corneum, traditional TDDS. Interestingly, multiscale suction-driven architectures (SDAs) inspired by bioinspired suction adhesion mechanisms provided innovative solutions these challenges. employ negative pressure enhance nanoscale skin-controllable skin adhesion, temporarily bypass barrier, facilitate deep penetration therapeutic agents, thereby, achieving goals increasing efficiency maximizing user convenience as a minimal invasive, needle-free platform. This review provides comprehensive overview patches emphasizes their integration multifunctional materials achieve stable controlled release. Next, we present cost-effective user-friendly patch devices optimization cupping without incorporation additional devices. Furthermore, that optimize need for Potential SDAs localized systemic challenging complex well future perspectives, discussed, along directions more patient-centric solutions.
Language: Английский
Citations
0
Journal of Nanobiotechnology, Journal Year: 2025, Volume and Issue: 23(1)
Published: April 7, 2025
Abstract Breast cancer is the most commonly diagnosed worldwide. Despite advancements in therapeutic modalities, its prognosis remains poor owing to complex clinical, pathological, and molecular characteristics. Sonodynamic therapy (SDT) a promising approach for tumor elimination, using sonosensitizers that preferentially accumulate tissues are activated by low-intensity ultrasound produce reactive oxygen species. However, clinical translation of SDT faces challenges, including limited efficiency resistance posed microenvironment. The emergence nanomedicine offers innovative strategies address these obstacles. This review discusses enhancing efficacy sonosensitizers, rational structural modifications, improved tumor-targeted enrichment, microenvironment remodeling, imaging-guided therapy. Additionally, SDT-based multimodal therapies, such as sono-chemotherapy, sono-immunotherapy, sono-photodynamic therapy, their potential applications breast treatment summarized. underlying mechanisms briefly outlined. Finally, this highlights current challenges prospects SDT, providing insights into future may improve outcomes cancer. Graphical abstract
Language: Английский
Citations
0
ACS Nano, Journal Year: 2025, Volume and Issue: unknown
Published: April 16, 2025
Wearable wound exudate sensors hold great promise for providing dynamic measurements of valuable biomarkers. However, no existing are able to achieve the fully integrated, skin-on, and detection raw oxygen (O2), which is closely related conditions also essential healing. Here, we report a integrated wearable biomimetic microfluidic tracker, capable skin-on sampling, monitoring O2 in addition uric acid, lactate, pH, temperature, wireless control through seamless integration specially designed microfluidic, sensing, electronic modules. We test performance device both bacterium-inoculated uninoculated wounds using mouse models. further assess its potential management healing process infected diabetic controlled experiments local hyperbaric treatment.
Language: Английский
Citations
0
Deleted Journal, Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 13, 2024
Abstract Wearable therapy represents a research frontier where material science, electrical engineering, and medical disciplines intersect, offering significant potential for remote portable healthcare. Unlike conventional approaches that rely on rigid materials, the ability to stretch is crucial therapeutic devices achieve enhanced mechanical adaptability. Moreover, conformable integration of these into body pivotal in establishing reliable interfaces long‐term treatment. These emerging provide an attractive platform developing new protocols do not disrupt daily activities. This review comprehensively overviews recent progress stretchable body‐conformable electronics wearable applications. The discussion begins with design fabrication through structural designs innovation. mechanisms adopted by are then systematically explored. Furthermore, article delineates characteristics devices, such as biocompatibility, secure skin attachment, effective moisture management. poised inspire innovative device treatment future technology.
Language: Английский
Citations
2
Materials Chemistry Frontiers, Journal Year: 2024, Volume and Issue: 8(23), P. 3877 - 3897
Published: Jan. 1, 2024
This paper reviews the potential of self-assembled phthalocyanine-based nano-photosensitizers for overcoming limitations photodynamic therapy (PDT) in treating hypoxic tumors.
Language: Английский
Citations
1
Sensors & Diagnostics, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 13, 2024
This review provides a summary and an outlook on the challenges prospects associated with commercialization of GFET technology in biosensing field.
Language: Английский
Citations
0