Development of a pH‐Responsive Antimicrobial and Potent Antioxidant Hydrogel for Accelerated Wound Healing: A Game Changer in Drug Delivery DOI Open Access
Qixiang Gui, Neng Ding,

Haimei Wu

et al.

Advanced Biology, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 14, 2024

Abstract Stimuli‐responsive hydrogels have the capability to alter their state in response changes physiological signals within application environment, providing distinct benefits drug delivery applications. Here, acidic pH typically found acutely infected wounds can be effectively managed by incorporating a pH‐responsive Ag + loaded system hydrogel, thereby ensuring efficient use and preventing potential toxicity from sudden release of silver ions. The antimicrobial composite hydrogel HAMA/GelMA‐CA/Ag provides some tissue adhesion accelerates wound healing. GelMA‐CA is synthesized modifying gelatin methacryloyl (GelMA) with caffeic acid (CA), while hyaluronic (HAMA) introduced prepare double network hydrogel. Silver nitrate then make it through formation coordination between polyphenolic structure exhibited excellent antioxidant properties strong activity against both Staphylococcus aureus (S. aureus) Escherichia coli (E. coli). Furthermore, accelerated promotion healing rat model S. aureus‐infected wounds. In conclusion, promising bioactive material that used as dressing promote

Language: Английский

Multifunctional Carbon Dots In Situ Confined Hydrogel for Optical Communication, Drug Delivery, pH Sensing, Nanozymatic Activity, and UV Shielding Applications DOI Creative Commons

Parham Khoshbakht Marvi,

Poushali Das, Arman Jafari

et al.

Advanced Healthcare Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 5, 2025

Abstract Inspired by the emerging potential of photoluminescent hydrogels, this work unlocks new avenues for advanced biosensing, bioimaging, and drug delivery applications. Carbon quantum dots (CDs) are deemed particularly promising among various optical dyes, enhancing polymeric networks with superior physical chemical properties. This study presents synthesis CDs derived from Prunella vulgaris , a natural plant resource, through single‐step hydrothermal process, followed their uniform integration into hydrogel matrices via an in situ free radical graft polymerization. The resulting CD‐integrated hydrogels exhibit multifunctionality biomedical applications, featuring diffusion‐controlled release mechanism, permit concurrent therapeutic agents, enabling real‐time monitoring over 32 h. In addition, these function as broad‐range pH sensor (pH 3–11), provide robust ultraviolet (UV) shielding, demonstrate nanozyme‐like peroxidase activity. Critically, biocompatibility tests confirm non‐cytotoxicity toward fibroblast cells, establishing candidates diverse These include wound dressings that monitor healing process detect infection sensing, promote nanozymatic activity, all while maintaining moist microenvironment. exceptional suitability smart delivery, effective UV‐blocking, innovative platforms vivo sensing bioimaging.

Language: Английский

Citations

3

Magnetic Polymeric Conduits in Biomedical Applications DOI Creative Commons
Sayan Ganguly, Shlomo Margel

Micromachines, Journal Year: 2025, Volume and Issue: 16(2), P. 174 - 174

Published: Jan. 31, 2025

Magnetic polymeric conduits are developing as revolutionary materials in regenerative medicine, providing exceptional benefits directing tissue healing, improving targeted medication administration, and facilitating remote control via external magnetic fields. The present article offers a thorough examination of current progress the design, construction, functionalization these hybrid systems. integration nanoparticles into matrices confers distinctive features, including regulated alignment, improved cellular motility, medicinal delivery, while preserving structural integrity. Moreover, incorporation multifunctional attributes, such electrical conductivity for cerebral stimulation optical characteristics real-time imaging, expands their range applications. Essential studies indicate that dimensions, morphology, surface chemistry, composition significantly affect biocompatibility, degrading characteristics, overall efficacy. Notwithstanding considerable advancements, issues concerning long-term biodegradability, scalability persist, addition to must uniform regulatory frameworks facilitate clinical translation. Progress additive manufacturing nanotechnology is overcoming obstacles, creation dynamic adaptive conduit structures designed particular biomedical requirements. conduits, by integrating usefulness safety, set transform therapies, presenting new avenue customized medicine advanced healthcare solutions.

Language: Английский

Citations

2

A tissue regeneration-promoting hydrogel dressing incorporating zirconium MOF loaded with curcumin for multi-modal healing of bacterial-infected wounds DOI
Xiaomin Wu,

Fengzhen Meng,

Zhuofeng Lin

et al.

Materials Today Chemistry, Journal Year: 2025, Volume and Issue: 44, P. 102568 - 102568

Published: Feb. 9, 2025

Language: Английский

Citations

1

Carbon-based nanozymes for cancer therapy and diagnosis: A review DOI Creative Commons
Marco Cordani, Jesús Fernández‐Lucas, Arezoo Khosravi

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 139704 - 139704

Published: Jan. 1, 2025

Language: Английский

Citations

0

Utilizing Chicken Egg White and L-Cysteine for Green Synthesis of Carbon Dots: Rapid and Cost-Effective Detection of Cu2+ Ions DOI Open Access
Pablo Eduardo Cardoso-Ávila, J. L. Pichardo-Molina

Materials, Journal Year: 2025, Volume and Issue: 18(3), P. 637 - 637

Published: Jan. 31, 2025

A novel green synthesis method was developed for sulfur-doped carbon dots (S-C-dots) using chicken egg white (CEW) and L-cysteine the rapid cost-effective detection of copper ions (Cu2+) in water. This one-pot, room-temperature, base-catalyzed approach eliminated need energy-intensive processes purification steps, adhering to principles chemistry. The synthesized S-C-dots were characterized UV-Vis, FT-IR, fluorescence, EDS, XRD, Z-potential analyses. Among six samples tested, A060 demonstrated superior properties, achieving a limit 3.3 ppb (52 nM) Cu2+ aqueous solutions. study highlights potential as eco-friendly, accessible, efficient tools monitoring heavy metal contamination drinking water, offering promising solution global water safety challenges.

Language: Английский

Citations

0

Facile Construction of Stable Photoluminescence Amorphous Colloidal Array Patterns by Infiltration-Assisted Assembly DOI
Hehua Hui, Ting Lü, Dongming Qi

et al.

Colloids and Surfaces A Physicochemical and Engineering Aspects, Journal Year: 2025, Volume and Issue: unknown, P. 136466 - 136466

Published: Feb. 1, 2025

Language: Английский

Citations

0

Mechanically Robust, Time-Programmable, Janus Hydrogel Actuator, and the Insights into Its Driving Principles DOI

J.C. Wang,

Yue Wu, Kewei Zhao

et al.

ACS Applied Polymer Materials, Journal Year: 2025, Volume and Issue: unknown

Published: March 11, 2025

Language: Английский

Citations

0

Molecular dynamics simulation of gas-liquid interface characteristics of trisiloxane and hydrocarbon surfactant mixed water-based foams DOI
Qingguo Wang,

Xing Zhang,

Weixiang Wang

et al.

Journal of Industrial and Engineering Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Language: Английский

Citations

0

Aqueous synthesis and characterization of emission tunable near-infrared second window emitting PbS quantum dots and its physicochemical interactions with graphene oxide and fluorinated derivative material DOI
Tushar Kanti Das, Sudip Karmakar, Goutam Pramanik

et al.

Materials Science and Engineering B, Journal Year: 2025, Volume and Issue: 317, P. 118211 - 118211

Published: March 14, 2025

Language: Английский

Citations

0

Detection of an oxidative stress metabolite associated with neurodegenerative diseases: effect of heteroatom doped antioxidant carbon dots DOI Creative Commons
Mohammad Tabish, Iram Malik, Abdulrahman Alshahrani

et al.

RSC Advances, Journal Year: 2025, Volume and Issue: 15(11), P. 8354 - 8366

Published: Jan. 1, 2025

Carbon dots (CDs) are neoteric forms of carbon nanostructures, and play a fundamental role in early diagnosis controlling neurological disorders (NDs).

Language: Английский

Citations

0