Harnessing biomaterials for advanced biosensor and bioelectronic devices development: From natural chromophores to biodegradable substrates and peptide-based detection of nanoplastics

MRS Advances, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 24, 2025

Abstract Biomaterials play a crucial role in advancing biosensor technologies for medical, environmental, and food safety applications. This study investigates natural biomaterials, such as food-derived chromophores, cellulose, peptides, high-performance biosensors bioelectronic devices. Chromophores, namely grape anthocyanins, are potential candidates the development of artificial retinal devices showing light-responsivity at 435 nm, close to human blue cone photoreceptors (420 nm), transient photo-current signals 15 nA/mm 2 (20 ms, blue-light pulse). Realized cellulose-silk fibroin (SF:CNCs)-based biodegradable substrates suitable flexible sustainable optoelectronic devices, transmittance over 40% (400 800 nm) good stress break (60 MPa 5%). Peptides, derived from enzymes, used biorecognition elements EGOFETs detecting polystyrene nanoplastics with sensitivity 60.3%/(mg/ml). Through use SF:CNCs-based substrates, peptide, new developed displaying promising applications biomedicine, green electronics, environmental pollution-monitoring. Graphical abstract

Language: Английский

Piezoelectric Biomaterials for Use in Bone Tissue Engineering—A Narrative Review

Journal of Biomedical Materials Research Part B Applied Biomaterials, Journal Year: 2025, Volume and Issue: 113(4)

Published: March 17, 2025

ABSTRACT To examine natural bone's bioelectrical traits, notably its piezoelectricity, and to look into how these characteristics influence bone growth repair. In the context of exploring potential piezoelectric biomaterials, such as biopolymers bio‐ceramics, towards orthopedic regeneration applications, research seeks evaluate significance piezoelectricity‐driven osteogenesis. The paper reviews recent on electrical dielectric properties, surface polarization/electrical stimulation effects interacting with cell activity effectiveness biomaterials support tissues' regenerative process. study includes a number materials, collagen, polyvinylidene fluoride (PVDF) barium titanate. applications organic polymers, polymers are particularly highlighted. Piezoelectric being shown in studies enhance cellular metabolism vitro well promote tissues vivo, especially when paired electric field or interface polarization. bio‐ceramics like magnesium silicate titanate, collagen PVDF, have possibilities for applications. However, there several challenges regarding manufacturing specific compositions having desired properties. This review highlighted special emphasis bioceramics. Therefore, types materials huge because they can mimic properties allow better advances tissue engineering medicine. date, little is known about their mechanism action, modifications needed improve efficacy clinical uptake.

Language: Английский