Advanced Synthesis & Catalysis,
Journal Year:
2019,
Volume and Issue:
361(14), P. 3318 - 3323
Published: May 1, 2019
Abstract
A
novel
aldehydic
C−H
functionalization
reaction
between
salicylaldehydes
and
sulfoxonium
ylides
has
been
developed
under
rhodium(III)
catalysis,
affording
coupling
products
in
moderate
to
good
yields.
plausible
mechanism
involving
C(
sp
2
)−H
activation
by
catalyzed
carbene
insertion
is
also
proposed.
It
was
found
that
the
followed
dehydrative
cyclization
able
produce
flavonoids
one‐pot.
magnified
image
ACS Catalysis,
Journal Year:
2020,
Volume and Issue:
10(17), P. 9747 - 9757
Published: Aug. 3, 2020
Transition-metal-catalyzed
C–H
activation
followed
by
oxidative
cyclization
with
unsaturated
coupling
partners
has
been
a
valuable
synthetic
tool
for
the
multiring
molecular
scaffolds.
This
Perspective
introduces
recent
progress
on
Cp*M-catalyzed
(M
=
Co,
Rh,
and
Ir)
direct
annulation
of
functionalized
arenes
terminal
alkynes
their
equivalents
through
bond
cleavage.
The
highlighted
examples
are
categorized
according
to
10
different
types
reagents
used
in
transformations.
representative
conditions,
selected
reaction
scope,
key
mechanistic
aspects
briefly
summarized.
Organic Letters,
Journal Year:
2019,
Volume and Issue:
21(12), P. 4812 - 4815
Published: June 13, 2019
A
novel
ruthenium-catalyzed
[5
+
1]
annulation
of
2-alkenylanilines
with
sulfoxonium
ylides
was
developed
for
the
rapid
assembly
highly
functionalized
quinolines.
This
new
catalytic
process
employs
challenging
but
synthetically
ideal
free
amino
functionality
to
achieve
alkenyl
C–H
activation
as
one-carbon
coupling
partners.
Various
2-acylquinolines
could
be
obtained
good
yields
and
excellent
functional
group
tolerance.
Moreover,
potential
synthetic
application
this
methodology
exemplified
by
several
chemical
transformations.
Organic Letters,
Journal Year:
2019,
Volume and Issue:
21(17), P. 6653 - 6657
Published: Aug. 19, 2019
A
rhodium-catalyzed
annulation
between
aroyl
sulfoxonium
ylides
and
anthranils
has
been
developed
to
synthesize
10H-indolo[1,2-a]indol-10-one
derivatives.
This
reaction
started
with
an
unpredented
(4
+
1)
toward
N-(2-formylphenyl)
indolones,
proceeding
the
sequential
ortho-amination
of
C–H
bond
in
by
insertion
N–H
carbene.
Finally,
Aldol
condensation
constructed
second
indole
ring.
procedure
features
formation
two
C–N
bonds
one
C═C
pot.
Organic Chemistry Frontiers,
Journal Year:
2019,
Volume and Issue:
6(8), P. 1183 - 1188
Published: Jan. 1, 2019
Ruthenium-catalyzed
selective
C–H
bond
activation
of
imidamides
and
annulation
sulfoxonium
ylides
were
achieved,
which
afforded
a
series
3-ketoindole
derivatives
in
good
yields,
with
functional
group
compatibility.
Chemistry - A European Journal,
Journal Year:
2020,
Volume and Issue:
26(44), P. 9749 - 9783
Published: June 18, 2020
Sequential,
domino
and
tandem
reactions
could
be
defined
as
a
sequence
of
synthetic
transformations
that
occur
one
after
the
other,
in
same
reaction
flask.
This
Review
highlights
recent
advances
at
overlap
two
worlds:
transition-metal
mediated
C-H
activation
trigger
cascade
reaction,
for
heterocycles
synthesis.
To
shed
some
light
on
this
intricate
"middle-earth",
focus
was
put
mechanism
rather
than
type
metal
or
chronological
order
reaction.
The
aim
is
to
separate,
then
highlight,
true
initiated
by
activation,
compared
other
examples
functionalization
heterocycle
syntheses.
Advanced Synthesis & Catalysis,
Journal Year:
2020,
Volume and Issue:
362(22), P. 4896 - 4990
Published: Aug. 19, 2020
Abstract
In
the
past
decades,
an
enormous
number
of
reports
have
been
dedicated
towards
synthesis
nitrogen
containing
heterocycles.
This
immense
interest
emerged
owing
to
their
wide
varieties
pharmacological
activities.
The
present
review
focused
on
isoquinoline
derivatives,
a
family
N
‐heterocycles
showing
broad
range
structural
diversity,
biological
and
pharmaceutical
progress
synthetic
strategies
using
versatile
approaches
are
discussed
in
details.
magnified
image
Organic Chemistry Frontiers,
Journal Year:
2022,
Volume and Issue:
9(16), P. 4388 - 4393
Published: Jan. 1, 2022
The
synthesis
of
3-trifluoromethylisoquinolinones
by
a
ruthenium(
ii
)-catalyzed
C–H
activation/annulation
reaction
benzoic
acids
and
CF
3
-imidoyl
sulfoxonium
ylides
has
been
achieved.
Asian Journal of Organic Chemistry,
Journal Year:
2022,
Volume and Issue:
11(4)
Published: March 23, 2022
Abstract
In
recent
years,
the
transition‐metal‐catalyzed
functionalization
reactions
of
sulfoxonium
ylides
have
been
explored
extensively
because
their
usefulness
as
carbene‐transfer
agents,
since
they
can
produce
metal
carbenes
through
catalysis.
Moreover,
are
safer
and
advantages
simple
handling
good
stability
over
other
counterparts
like
diazo‐compounds.
This
review
article
attempts
to
highlight
advances
in
metal‐catalyzed
C−H
ylides.
Organic Letters,
Journal Year:
2019,
Volume and Issue:
21(4), P. 872 - 875
Published: Feb. 6, 2019
The
first
examples
of
palladium-catalyzed
allylic
C–H
oxidative
allylation
sulfoxonium
ylides
to
afford
the
corresponding
conjugated
dienones
with
moderate
good
yields
have
been
established.
features
this
novel
conversion
include
mild
reaction
conditions,
wide
substrate
scope,
and
excellent
regioselectivity.
