European Journal of Organic Chemistry,
Journal Year:
2022,
Volume and Issue:
2022(43)
Published: Oct. 21, 2022
Abstract
The
hydroxyl‐directed
iridium‐catalyzed
peri
‐selective
C−H
bond
activation
to
synthesize
substituted
pyrano[2,3,4‐
de
]chromen‐2‐ones
and
further
chalcogenylation
under
blue
light
irradiation
has
been
realized
efficiently.
Most
products
of
polycyclic
pyrans
corresponding
chalcogenated
derivatives
with
various
substituents
were
achieved
in
good
excellent
yields.
Preliminary
mechanistic
studies
suggest
that
this
transformation
may
pass
through
a
five‐membered
iridacycle
intermediate
containing
an
O−Ir
σ‐bond
photocatalytic
free
radical
process.
Chinese Journal of Organic Chemistry,
Journal Year:
2023,
Volume and Issue:
43(8), P. 2905 - 2905
Published: Jan. 1, 2023
A
Rh(III)-catalyzed
synthesis
of
arylacetaldehydes
via
C-H
formylmethylation
with
vinylene
carbonate
has
been
developed.The
reaction
proceeded
smoothly
to
give
C7-functionalized
N-(2-pyrimidyl)-indolines
in
moderate
good
yields.This
protocol
features
simple
system,
excellent
regioselectivity,
and
functional
group
compatibility.
New Journal of Chemistry,
Journal Year:
2023,
Volume and Issue:
47(43), P. 19822 - 19826
Published: Jan. 1, 2023
A
DBU-promoted
three-component
cascade
annulation
of
3-oxo-3-phenylpropanenitriles,
(
E
)-chalcones
and
selenium
powder
has
been
proposed
for
the
synthesis
tetrasubstituted
selenophenes.
European Journal of Organic Chemistry,
Journal Year:
2023,
Volume and Issue:
27(5)
Published: Dec. 20, 2023
Abstract
Arylacetaldehydes
and
its
corresponding
esters
are
fundamental
structural
motifs
widespread
in
natural
products
pharmaceuticals.
Herein,
we
developed
a
ruthenium(II)‐catalyzed
direct
formylmethylation
sequential
dehydrogenative
esterification
of
phthalazinones
by
adopting
vinylene
carbonate
as
C2
synthon
(formylmethyl
equivalent).
The
reaction
is
compatible
with
repertoire
substrates
bearing
both
electron‐donating
electron‐withdrawing
substituents.
Strikingly,
the
obtained
governed
additive
used.
A
number
control
experiments
conducted
to
elucidate
mechanism.
Furthermore,
an
important
highlight
confirmation
possible
intermediates
mass
spectrometry.
Asian Journal of Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 18, 2024
Abstract
The
base‐induced
[3+3]
annulation
reaction
of
phenacyl
phosphonium
ylides
with
cyclopropenones
has
been
proposed.
Various
polysubstituted
2‐pyrones
are
achieved
in
moderate
to
good
yields
through
C−P
bond
cleavage
and
C−O/C−C
coupling
under
simple
easy‐to‐operate
conditions.
synthetic
application
mechanism
have
also
preliminarily
explored
gain
a
deeper
understanding
this
strategy
practicality
details.
This
protocol
offers
an
alternative
approach
for
the
synthesis
useful
2‐pyrone
derivatives.
European Journal of Organic Chemistry,
Journal Year:
2022,
Volume and Issue:
2022(43)
Published: Oct. 21, 2022
Abstract
The
hydroxyl‐directed
iridium‐catalyzed
peri
‐selective
C−H
bond
activation
to
synthesize
substituted
pyrano[2,3,4‐
de
]chromen‐2‐ones
and
further
chalcogenylation
under
blue
light
irradiation
has
been
realized
efficiently.
Most
products
of
polycyclic
pyrans
corresponding
chalcogenated
derivatives
with
various
substituents
were
achieved
in
good
excellent
yields.
Preliminary
mechanistic
studies
suggest
that
this
transformation
may
pass
through
a
five‐membered
iridacycle
intermediate
containing
an
O−Ir
σ‐bond
photocatalytic
free
radical
process.
