Chemistry Letters, Journal Year: 2024, Volume and Issue: 53(1)

Published: Jan. 1, 2024

Abstract A transition metal-free strategy is reported for the site-selective O-arylation of cyclic 1,3-dicarbonyls with polyfluoroarenes. This method offers a straightforward and alternative pathway synthesis aryl ethers, accommodating wide array functional groups. Furthermore, practical value this methodology underscored by its facile scalability to gram-level reactions, potential diverse synthetic applications, aptitude complex molecules modifications.

Language: Английский