“On-water” defluorinative cyclization of trifluoromethyl enones with phosphine oxides: synthesis of polysubstituted furans
Man-Hang Feng,
No information about this author
Shu-Ji Gao,
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M Kellis
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et al.
Organic Chemistry Frontiers,
Journal Year:
2024,
Volume and Issue:
11(14), P. 3974 - 3981
Published: Jan. 1, 2024
A
defluorinative
cyclization
of
readily
available
trifluoromethyl
enones
with
phosphine
oxides
for
the
synthesis
polysubstituted
furans
is
developed
in
a
pure
water
solution.
Language: Английский
Water-promoted defluorinative synthesis of fluoroalkylated 1,5-diazapentadienes by using (NH4)2CO3 as an NH2 and NH source
Wei Han,
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Yulan Chen,
No information about this author
Xi Tang
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et al.
Green Chemistry,
Journal Year:
2023,
Volume and Issue:
25(23), P. 9672 - 9679
Published: Jan. 1, 2023
A
H
2
O-promoted
and
(NH
4
)
CO
3
-enabled
defluoroiminization
reaction
of
fluoroalkyl
alkenes
for
the
synthesis
fluoroalkylated
1,5-diazapentadienes
has
been
developed.
Language: Английский
Sulfonylation of 2-Haloquinolines with Sulfonyl Hydrazides in Water for Accessing 2-Sulfonyl Quinolines under Catalyst-, Reductant-, and Additive-Free Conditions
Bo‐Jie Huo,
No information about this author
Yuan-Shuai Wu,
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Chengping Miao
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et al.
Tetrahedron,
Journal Year:
2025,
Volume and Issue:
unknown, P. 134705 - 134705
Published: May 1, 2025
Language: Английский
Heteroarylation of Organophosphonium Salts with Indoles in Water: Synthesis of Symmetrical and Unsymmetrical 3,3'‐Bisindolylmethane Derivatives
Xin-Long Luo,
No information about this author
Wen-Jun Ji,
No information about this author
Zi-Lun Yu
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et al.
European Journal of Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 16, 2024
Abstract
A
method
for
the
synthesis
of
symmetrical
and
unsymmetrical
3,3′‐bis(indolyl)methanes
(3,3′‐BIMs)
has
been
developed
through
direct
heteroarylation
indolyl‐containing
di(hetero)aryl
phosphonium
salts
with
indole
derivatives
in
aqueous
media.
This
metal‐free
reaction
proceeds
smoothly
under
mild
conditions,
eliminating
need
hazardous
solvents
expensive
additives/catalysts
typically
used
conventional
routes,
thereby
highlighting
synthetic
practicality
efficiency
process.
The
success
this
approach
is
largely
attributed
to
role
water
as
a
promoter,
facilitating
C−P
bond
functionalization
salts.
Furthermore,
demonstrates
broad
substrate
scope,
good
functional
group
tolerance,
excellent
scalability.
Moreover,
protocol
can
also
be
extended
triindolylmethane
compound
diarylmethylated
indole.
Language: Английский
Vigorously Stirred La2O3 Suspensions for Michael Additions in Water
Tomoya Hisada,
No information about this author
Rina Osada,
No information about this author
Taku Kitanosono
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et al.
Chemical Communications,
Journal Year:
2024,
Volume and Issue:
60(73), P. 9994 - 9996
Published: Jan. 1, 2024
Vigorously
stirred
La
2
O
3
suspensions
in
water
demonstrated
exceptional
efficiency
(
e.g.
high
yields,
short
reaction
times)
for
carbon–carbon
bond
formation.
Water
proved
irreplaceable
by
organic
solvents
despite
the
reactant(s)
being
immiscible.
Language: Английский