Advances in Self-Organized Total Synthesis of Natural Products DOI
Lisheng Wang, Jia‐Chen Xiang, An‐Xin Wu

et al.

Chemical Communications, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

In this review, we account for the definition, delimitation, and categorization of self-organized total synthesis then elucidate a comprehensive understanding synthetic strategy based on our intensive explorations.

Language: Английский

One-Pot Total Synthesis of Natural Products Nitramarine, Nitraridine, and Analogues via a Cascade Oxidation/Pictet–Spengler Condensation/Annulation Process DOI

Song Yingchun,

Wenhui Cao,

Ming‐Xuan Wang

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(17), P. 12832 - 12841

Published: Aug. 9, 2024

A cascade oxidation/Pictet–Spengler condensation/annulation process has been developed for the one-pot total synthesis of nitramarine, nitraridine, and their analogues. The procedure proceeded with easily available quinolines tryptophan derivatives. simple metal-free approach, wide substrate scope, functional group tolerance make it applicable diverse bioactive Furthermore, bioactivity evaluation identified two promising leading compounds 5d 5e potent antitumor proliferative activity against breast cancer cells.

Language: Английский

Citations

3
Recent Advances in the Research on Luotonins A, B, and E DOI Creative Commons

Ján Gettler,

Martin Markovič, Peter Koóš

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(15), P. 3522 - 3522

Published: July 26, 2024

This digest review summarises the most recent progress in study on luotonins A, B and E. The literature covered this overview spans from January 2012 to April 2024 presents synthetic methodologies for assembly of quinolinopyrrolo-quinazoline scaffold, structural motifs present B, E, evaluation biological activities their derivatives analogues.

Language: Английский

Citations

1
A Computational mechanistic study on the Ni-Catalyzed Asymmetric Alkynyl Propyl Hydroxyaminations: Origin of Enantioselectivity and Further Rational Design DOI
Yuqing Huang,

Manman Zhu,

Shuqi Zhang

et al.

New Journal of Chemistry, Journal Year: 2024, Volume and Issue: 48(28), P. 12565 - 12574

Published: Jan. 1, 2024

DFT calculations were conduct to elucidate the catalytic mechanism of target asymmetric propargylic substitution (APS) reaction. Moreover, we rationally designed a more efficient axial chiral phosphine ligand for APS

Language: Английский

Citations

0
Advances in Self-Organized Total Synthesis of Natural Products DOI
Lisheng Wang, Jia‐Chen Xiang, An‐Xin Wu

et al.

Chemical Communications, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

In this review, we account for the definition, delimitation, and categorization of self-organized total synthesis then elucidate a comprehensive understanding synthetic strategy based on our intensive explorations.

Language: Английский

Citations

0