Photoinduced radical C H alkylation by sulfoxonium, sulfonium, selenium and pyridinium ylides as new HAT organocatalysts DOI
Shuwen Chen, Huibin Qiu,

Jingwen Jia

et al.

Tetrahedron Letters, Journal Year: 2025, Volume and Issue: unknown, P. 155590 - 155590

Published: May 1, 2025

Language: Английский

Ex Situ Synthesis of N-Capped Peptides in the Solution Phase via Palladium-Catalyzed Aminocarbonylation Utilizing Chloroform-COware DOI
Aman Singh Barahdia,

Karuna Thakare,

Rahul Jain

et al.

The Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 28, 2025

We report the synthesis of N-capped peptides under mild conditions using oxidative aminocarbonylation aryl iodides and peptide esters as nucleophiles in solution phase. Ex situ chloroform chamber A generates CO, which diffuses to B, contains other reactants. This method offers at 80 °C for 12 h. synthesized 36 this method, including an anticancer drug bortezomib analogue, with isolated yield ranging from 52 91%. The present gives easy access previously inaccessible N-capping groups, heteroaromatic ring-capped enable robust analogue designs peptide-based discovery.

Language: Английский

Citations

1
Organic Catalysts and Ligands Derived from Amino Acids and Peptides DOI

Lipat Kaur,

Karuna Thakare,

Aman Singh Barahdia

et al.

Tetrahedron, Journal Year: 2025, Volume and Issue: unknown, P. 134671 - 134671

Published: April 1, 2025

Language: Английский

Citations

0
Photoinduced radical C H alkylation by sulfoxonium, sulfonium, selenium and pyridinium ylides as new HAT organocatalysts DOI
Shuwen Chen, Huibin Qiu,

Jingwen Jia

et al.

Tetrahedron Letters, Journal Year: 2025, Volume and Issue: unknown, P. 155590 - 155590

Published: May 1, 2025

Language: Английский

Citations

0