Advanced Synthesis & Catalysis, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 17, 2024

Abstract Visible light‐induced site‐selective C−H alkylation and alkenylation of 2‐aryl heteroarenes with maleimides at room temperature via dual catalysis in an aqueous medium has been disclosed. This operationally simple mild approach enables the selective formation products up to 92% yield under silver‐free conditions excellent substrate scope. For mechanistic examination, KIE, H/D labeling experiments, light on‐off quantum measurements were carried out. Moreover, present for is suitable scalable synthesis.

Language: Английский