Synthesis and Spectral Studies of Iron‐Catalyzed Multicomponent Synthesis of 4‑Phosphorylated 4H‑Chromenes from 2‐Hydroxybenzyl Alcohols
ChemistrySelect,
Journal Year:
2025,
Volume and Issue:
10(5)
Published: Jan. 30, 2025
Abstract
A
facile,
mild,
effective,
and
multicomponent
protocol
for
the
production
of
4‑phosphorylated‐4H‑chromenes
through
an
aldol
condensation,
Michael
addition,
cyclization
was
established.
The
C─C,
C─P,
C─O
bonds
were
constructed
during
reaction
to
produce
desired
product
from
2‐hydroxybenzyl
alcohols.
synthesized
compounds
characterized
by
standard
techniques.
important
features
this
are
operational
simplicity,
moderate
conditions,
use
a
low‐cost
iron
complex,
high
atom
economy.
Language: Английский
Vicinal diphosphorylation of enaminones with diaryl phosphine oxides via AlCl3-mediated C N bond cleavage
Xin Jin,
No information about this author
An Yong,
No information about this author
Jia Chen
No information about this author
et al.
Tetrahedron Letters,
Journal Year:
2025,
Volume and Issue:
158, P. 155472 - 155472
Published: Feb. 20, 2025
Language: Английский
Eco-Friendly and Efficient Synthesis of 2-Hydroxy-3-Hydrazono-Chromones Through α,β-C(sp2)–H Bond Difunctionalization/Chromone Annulation Reaction of o-Hydroxyaryl Enaminones, Water, and Aryldiazonium Salts
Xiaohong Wang,
No information about this author
Menglin Peng,
No information about this author
Yijin Wang
No information about this author
et al.
Molecules,
Journal Year:
2025,
Volume and Issue:
30(6), P. 1194 - 1194
Published: March 7, 2025
A
novel,
eco-friendly,
and
efficient
method
for
constructing
2,3-disubstituted
chromone
skeletons
from
readily
available
water,
o-hydroxyaryl
enaminones
(o-HPEs),
aryldiazonium
salts
has
been
developed
under
mild
reaction
conditions.
This
α,β-C(sp2)–H
bond
difunctionalization/chromone
annulation
strategy
is
achieved
by
building
two
C(sp3)–O
bonds
a
C(sp2)-N
bond,
which
provides
practical
pathway
the
preparation
of
2-hydroxy-3-hydrazono-chromones
in
moderate
to
excellent
yields,
enabling
broad
substrate
scope
good
functional
group
tolerance,
as
well
gram-scale
synthesis.
protocol
offers
valuable
tool
synthesizing
diverse
functionalized
chromones
with
potential
applications
drug
discovery
industrial
Language: Английский
Recent Advances in Site Selective Transformations of β-Enaminones via C-H Functionalization/Annulation
Organic & Biomolecular Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Jan. 1, 2024
β-Enaminone
transformation
strategies
are
widely
employed
in
the
synthesis
of
numerous
biologically
active
drugs
and
natural
products,
highlighting
their
significance
medicinal
chemistry.
Language: Английский
An update on the advances in chromone and the derivatives synthesis based on the key chromone annulation of o-hydroxyaryl enaminones
Chinese Chemical Letters,
Journal Year:
2024,
Volume and Issue:
unknown, P. 110784 - 110784
Published: Dec. 1, 2024
Language: Английский
Site Specific C3‐Alkenylation of Indoles Mediated by in situ C‐H Iodination
Yongli Zhao,
No information about this author
Dingsheng Cao,
No information about this author
Jie‐Ping Wan
No information about this author
et al.
Asian Journal of Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 29, 2024
Abstract
The
C3‐alkenylation
of
indoles
have
been
developed
by
means
a
novel
in
situ
iodination
tactic
which
is
capable
mediating
the
Heck
coupling
with
alkenes.
method
features
specific
site‐selectivity
oriented
C−I
bond,
high‐step
efficiency
without
pre‐functionalization
for
C‐halogen
bond
construction,
as
well
highly
general
tolerance
to
different
terminal
alkenes,
including
unactivated
acrylates,
acrylic
acid,
vinyl
sulfone
functionalized
natural
products.
Language: Английский